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PNAS 119 (8) e2113947119 | https://doi.org/10.1073/pnas.2113947119
Environmental exposure to active pharmaceutical ingredients (APIs) can have negative effects on the health of ecosystems and humans. While numerous studies have monitored APIs in rivers, these employ different analytical methods, m
...
easure different APIs, and have ignored many of the countries of the world. This makes it difficult to quantify the scale of the problem from a global perspective. Furthermore, comparison of the existing data, generated for different studies/regions/continents, is challenging due to the vast differences between the analytical methodologies employed. Here, we present a global-scale study of API pollution in 258 of the world’s rivers, representing the environmental influence of 471.4 million people across 137 geographic regions. Samples were obtained from 1,052 locations in 104 countries (representing all continents and 36 countries not previously studied for API contamination) and analyzed for 61 APIs. Highest cumulative API concentrations were observed in sub-Saharan Africa, south Asia, and South America. The most contaminated sites were in low- to middle-income countries and were associated with areas with poor wastewater and waste management infrastructure and pharmaceutical manufacturing. The most frequently detected APIs were carbamazepine, metformin, and caffeine (a compound also arising from lifestyle use), which were detected at over half of the sites monitored. Concentrations of at least one API at 25.7% of the sampling sites were greater than concentrations considered safe for aquatic organisms, or which are of concern in terms of selection for antimicrobial resistance. Therefore, pharmaceutical pollution poses a global threat to environmental and human health, as well as to delivery of the United Nations Sustainable Development Goals.
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The Sphere Handbook in Ukrainian
recommended
The Ukrainian translation of the Handbook was done by the Rev Marian and Dr Roman Curkowskyj Foundation. Established in 1990 in Toronto, Canada, the Foundation supports the advancement of education, notably through the publication of works in Ukrainian. 2011 Edition.
Antibiotics 2022, 11(3), 329; https://doi.org/10.3390/antibiotics11030329.
The authors found that the most-represented antibiotics on the Rwandan market were amoxicillin, co-trimoxazole and cloxacillin. No counterfeit antibiotics were found in this study. However, substandard batches with moderate
...
deviations were found, suggesting that regular quality control of antibiotics is needed in Rwanda.
more
Together for One Health. Building on the momentum of increased collaboration, the WHO, FAO, OIE and UNEP have developed a Strategic Framework for collaboration on antimicrobial resistance (AMR). This Framework reflects the joint work of the four organizations to advance a One Health response to AMR
...
at the global, regional and country level. It broadly supports the implementation of the five pillars of the Global Action Plan on AMR, as well as strengthening global AMR governance.
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National-scale databases and reliability issue
Background report
2016 ASCO EDUCATIONAL BOOK | asco.org/edbo
The Infection Prevention and Control (IPC) Legal Framework comes before the Specialized Technical Committee on Health and Drug Control for adoption and endorsement. The IPC Legal Framework is designed to guide Member States in the review and strengthening of laws and policies that support IPC at bot
...
h the national level and in healthcare facilities. In developing this IPC Legal Framework, the Africa Centres for Disease Control and Prevention (Africa CDC)
is furthering its mandates to harmonize disease control and prevention policies and promote the prevention and control of diseases by building capacity of public health institutions in Members States.
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The Lancet Regional Health - Americas 2022;00: 100248 Published online xxx https://doi.org/10.1016/j.lana.2022.100248.
The Lancet Countdown report, discuss the overlapping social, climate and health challenges in Latin America and the Caribbean, and urge multisectoral and political action to trans
...
form these challenges into opportunities through adaptation and mitigation measures that place peoples’ health and wellbeing at the centre of public policies. Latin American and Caribbean governments are called upon to promote climate-resilient health care systems with adaptation plans that are tailored to guarantee quality access to care for all in this viewpoint.
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The Statistical Yearbook for Latin America and the Caribbean of ECLAC presents a set of basic statistics on the economic, sociodemographic and environmental situation of the region during a specific time period.
February 2020Earth's Future 8(2):e2019EF001377.The water planetary boundary attempts to provide a global limit to anthropogenic water cycle modifications, but it has been challenging to translate and apply it to the regional and local scales at which water problems and management typically occur. We
...
develop a cross‐scale approach by which the water planetary boundary could guide sustainable water management and governance at subglobal contexts defined by physical features (e.g., watershed or aquifer), political borders (e.g., city, nation, or group of nations), or commercial entities (e.g., corporation, trade group, or financial institution).
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Journal of Land Use Science, 16:3, 223-239, DOI: 10.1080/1747423X.2021.1933226
The American Journal of Tropical Medicine and Hygiene Volume 106: Issue 1 p.12-14.he piece highlights a body of research that suggests tiny plastic particles could disrupt immune and endocrine systems, damage organs, and cause other health problems. “Without a fundamental reimagining of global
...
industrial practices, we will continue to see dire impacts on the climate, the planet and our health
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Waste Management & Research 39(1) DOI: 10.1177/0734242X211029175
Constraints, Technologies, Policies and Processes
Transformation and outlook
Promoting health and well-being throughout Europe
Climate Smart Agriculture provides an excellent opportunity for the transformation by uniting agriculture, development and climate change under a common agenda through integrating the three dimensions of sustainable development (economic, social and environmental) by jointly addressing food security
...
and climate challenge
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Injection Safety and Safe Disposal of Medical Waste National Communication Strategy and Health Care Waste Management Standard
Operating Procedures (SOPs).
The overall objective of the consultancy was to review and align the three national technical and communication guiding documents on HCWM to th
...
e WHO Blue Book and other global standards and recommendations. The specific objectives of the assignment were ; to establish how well aligned the Kenya Healthcare Waste Management Guidelines, 2011, are to the WHO Blue Book on healthcare waste management, global recommendations and other global conventions on environmental protection; to establish the extent to which the Kenya Injection Safety and Safe Disposal of Medical Waste National Communication Strategy is aligned to the National Health Communication Guidelines, 2013; to determine the extent to which the current Standard Operating Procedures are aligned to the best available technologies (BAT) and best environmental practices (BEP) and international practices; and to assess current health care waste management practices at the health facilities supported by the GEF project.
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