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Therapeutics and COVID-19 (Living Guideline, 10 November 2023)

World Health Organization WHO (2023) C_WHO

WHO has updated its guidelines for COVID-19 therapeutics, with revised recommendations for patients with non-severe COVID-19. This is the 13th update to these guidelines. Updated risk rates for hospital admission in patients with non-severe COVID-19 The guidance includes updated risk rates for... hospital admission in patients with non-severe COVID-19. The current COVID-19 virus variants tend to cause less severe disease while immunity levels are higher due to vaccination, leading to lower risks of severe illness and death for most patients. This update includes new baseline risk estimates for hospital admission in patients with non-severe COVID-19. The new ‘moderate risk’ category now includes people previously considered to be high risk including older people and/or those with chronic conditions, disabilities, and comorbidities of chronic disease. The updated risk estimates will assist healthcare professionals to identify individuals at high, moderate or low risk of hospital admission, and to tailor treatment according to WHO guidelines: **High: **People who are immunosuppressed remain at higher risk if they contract COVID-19, with an estimated hospitalization rate of 6%. **Moderate: **People over 65 years old, those with conditions like obesity, diabetes and/or chronic conditions including chronic obstructive pulmonary disease, kidney or liver disease, cancer, people with disabilities and those with comorbidities of chronic disease are at moderate risk, with an estimated hospitalization rate of 3%. Low: Those who are not in the high or moderate risk categories are at low risk of hospitalization (0.5%). Most people are low risk. Review of COVID-19 treatments for people with non-severe COVID-19 WHO continues to strongly recommend nirmatrelvir-ritonavir (also known by its brand name ‘Paxlovid’) for people at high-risk and moderate risk of hospitalization. The recommendations state that nirmatrelvir-ritonavir is considered the best choice for most eligible patients, given its therapeutic benefits, ease of administration and fewer concerns about potential harms. Nirmatrelvir-ritonavir was first recommended by WHO in April 2022. If nirmatrelvir-ritonavir is not available to patients at high-risk of hospitalization, WHO suggests the use of molnupiravir or remdesivir instead. WHO suggests against the use of molnupiravir and remdesivir for patients at moderate risk, judging the potential harms to outweigh the limited benefits in patients at moderate risk of hospital admission. For people at low risk of hospitalization, WHO does not recommend any antiviral therapy. Symptoms like fever and pain can continue to be managed with analgesics like paracetamol. WHO also recommends against use of a new antiviral (VV116) for patients, except in clinical trials. The update also includes a strong recommendation against the use of ivermectin for patients with non-severe COVID-19. WHO continues to advise that in patients with severe or critical COVID-19, ivermectin should only be used in clinical trials. more

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A Roadmap on the Prevention of Cardiovascular Disease Among People Living With Diabetes

Mitchell, S.; Malanda, B.; Damasceno, A. et al. World Heart Federation (2019) CC

In 2014, the World Heart Federation (WHF) launched an initiative to develop a series of Roadmaps [1e6]. Their aim is to identify potential roadblocks on the pathway to effective prevention, detection, and management of cardiovascular disease (CVD), along with evidence-based solutions to overcome... more

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Guidance on development and implementation of a national deployment and vaccination plan for vaccines against pandemic influenza and other respiratory viruses of pandemic potential

World Health Organization WHO (2023) C_WHO

Vaccines are powerful weapons in the fight against pandemic viruses as shown by responses to both the 2009 H1N1 influenza and the COVID-19 pandemics. However, planning for accessing, allocating and deploying vaccines in a pandemic situation is a complex endeavour, beset with multiple challenges at a... more

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Compendium of WHO and other UN guidance on health and environment: version with International Classification of Health Intervention (‎ICHI)‎ codes

World Health Organization WHO (2024) C_WHO

In this version of the compendium, each guidance is coded using the International Classification of Health Interventions (ICHI). The compendium provides a systematic compilation of published guidance from WHO and other UN organizations on health and environment. Guidance on policies and actions a... more

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National Guideline For Emergency Nutrition Intervention (May 2022)

Government of Ethiopia (2022) CC

Humanitarian crises exacerbate nutritional risks and often lead to an increase in acute malnutrition. Emergencies include both manmade (conflict) and natural disasters (floods, drought, cyclones, typhoons, earthquakes, volcanic eruptions, etc.). Complex emergencies are combinations of both manmade a... more

Pocketbook for management of Diabetes in Childhood and Adolescence in under-resourced Countries

Ogle, G.; Middlehurst, A.; Silink, M.; Hanas, R. International Diabetes Federation (2017) CC2

The document "Pocketbook for Management of Diabetes in Childhood and Adolescence in Under-Resourced Countries" (2nd Edition) provides practical guidelines for managing diabetes in children and adolescents, particularly in resource-limited settings. It covers key topics like diagnosing and treating d... more

Global air pollution exposure and poverty

Rentschler, J.; Leonova, N. Nature Communications (2023) CC

Air pollution is one of the leading causes of health complications and mortality worldwide, especially affecting lower-income groups, who tend to be more exposed and vulnerable. This study documents the relationship between ambient air pollution exposure and poverty in 211 countries and territories.... more

Liste nationale des médicaments essentiels et autres produits de santé (2023)

World Health Organisation (WHO) (2023) C_WHO

Les médicaments essentiels sont ceux qui répondent aux besoins de santé prioritaires d'une population. Conformément aux recommandations de l'Organisation mondiale de la Santé (OMS), des listes nationales de médicaments essentiels sont régulièrement révisées, puis mises à la disposition de... more

NCD Alliance Advocacy Priorities - For the 2023 United Nations High-Level Meeting on Universal Health Coverage

NCD Alliance NCD Alliance (2023) CC2

The document is a policy brief by the NCD Alliance for the 2023 United Nations High-Level Meeting on Universal Health Coverage (UHC). It highlights the importance of integrating non-communicable diseases (NCDs) into UHC efforts, with the goal of ensuring equitable health access worldwide.

Sustainable management of radiotherapy facilities and equipment

World Health Organization (WHO) World Health Organization (WHO) (2023) C_WHO

The document, "Sustainable Management of Radiotherapy Facilities and Equipment," by WHO and IAEA, provides guidelines for managing radiotherapy equipment and facilities to ensure effective and safe cancer treatment. It covers essential aspects like preventive and corrective maintenance, funding, inf... more

Report on the epidemiological situation of dengue in the Americas, June 2024

Pan American Health Organization PAHO (2024) C_WHO

Between epidemiological weeks (EW) 1 and 22 of 2024, a total of 9,541,015 suspected cases of dengue were reported, resulting in a cumulative incidence of 1,011 per 100,000 population. This represents an increase of 230% compared to the same period in 2023 and 421% compared to the average of the last... more

Access to essential respiratory medications remains elusive in LMICs

Karmali, D.; Siddharthan, T. (2022) CC

Over 90% of the morbidity and mortality related to chronic obstructive pulmonary disease (COPD) and asthma occurs in low-income and middle-income countries (LMICs) due to well documented factors including decreased access to screening, trained health professionals, and therapies for disease manageme... more

Социальное и психическое здоровье пожилых женщин как часть стратегии спасения людей: Новые вызовы для социальной работы

O. A. Anikeeva, S. N. Fomina, Ya. V. Shimanovskaya (2021) C1

Стратегия народосбережения в Российской Федерации — один из основных документов государственной социальной политики. Она может быть реализована различными путя... more

United Nations Framework Convention on Climate Change: Guidance from the Conference of the Parties and Responses by the Global Environment Facility, COP1 - COP28

Global Environment Facility GEF (2024) CC

The United Nations Framework Convention on Climate Change (UNFCCC) established its Financial Mechanism to facilitate the provision and transfer of resources from developed to developing countries. The Global Environment Facility became the first operating entity of the Financial Mechanism after the ... more

Реабилитационный потенциал социально-психологического сопровождения семей с проблемами алкогольной или наркотической зависимости

Барцалкина В.В. et al. (2022) CC

Реабилитационный потенциал социально-психологического сопровождения семей с проблемами химической зависимости предлагается рассматривать как ресурс преодолен... more

Progress in snakebite envenoming data reporting: challenges and opportunities

Nikiema Nidjergou, Y.N.; et al. World Health Organization WHO (2024) C_WHO

Progrès dans la notification des données sur l’envenimation par morsure de serpent: défis et opportunités. Englisch/Francais. WEEKLY EPIDEMIOLOGICAL RECORD, NOS. 51/52, 20 DECEMBER 2024, pp. 770-775

Global report on neglected tropical diseases 2024: executive summary

World Health Organization WHO (2024) C_WHO

Three full years have passed since the launch of the road map for neglected tropical diseases 2021–2030. Data on progress begin to provide insights into the prospects of attaining the 2030 targets.

How immunization strengthens the fight against antimicrobial resistance

World Health Organization WHO (2024) C_WHO

Vaccines contribute to the battle against antimicrobial resistance (AMR) by preventing infections and thereby reducing antimicrobial use and the incidence of disease from resistant pathogens. By preventing infection transmission, vaccines extend population protection by also reducing the risk of inf... more

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Guidelines for laboratory and field-testing of long-lasting insecticidal nets
recommended

World Health Organization (2013) C_WHO

Trachoma Control a Guide for Programme Managers

Anthony W. Solomon, Marcia Zondervan, Hannah Kuper, et al. WHO, London School of Hygiene & Tropical Medicine, and the International Trachoma Initiative (2006)

Guidelines for laboratory and field-testing of long-lasting insecticidal nets recommended

Guidelines for laboratory and field-testing of long-lasting insecticidal nets
recommended