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Monitoring the elimination of human African trypanosomiasis at continental and country level: Update to 2018

Franco, JR.; Cecchi, G.; Priotto, G.; Paone, M.; Diarra, A. et al. (2020) CC

Over the past twenty years, huge efforts made by a broad coalition of stakeholders curbed the last epidemic and brought the disease to the brink of elimination. In this paper, the latest figures on disease occurrence, geographical distribution and control activities are presented. Strong evidence in... more

Guidance on Selection and Use of One Health Operational Tools

Food and Agriculture Organization of the United Nations FAO; UN Environment Programme UNEP; World Health Organization WHO; World Organisation for Animal Health WOAH (2024) C_WHO

The One Health (OH) High-Level Expert Panel (OHHLEP) of the Quadripartite Organizations defined OH as an integrated, unifying approach that aims to sustainably balance and optimize the health of peo... more

Integrated Family Planning and Immunization Service Delivery at Health Facility and Community Sites in Dowa and Ntchisi Districts of Malawi: A Mixed Methods Process Evaluation

Cooper, C. M.; Wille, J.; Shire, S.; et al. (2020) CC2

The Government of Malawi’s Health Sector Strategic Plan II highlights the importance of service integration; however, in practice, this has not been fully realized. We conducted a mixed methods evaluation of efforts to systematically implement int... more

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The Core Elements of Human Antibiotic Stewardship Programs in Resource-Limited Settings: National and Hospital Levels
recommended

Centers for Disease Control and Prevention CDC (2018) C_CDC

Formularies are lists of antibiotics that are suggested for certain healthcare settings. In developing a recommended formulary, countries should consider the needs of patients and facilities where they receive care. For example, clinicians in rural ... more

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Nature-Based Solutions and Protected Areas to Improve Urban Biodiversity and Health

MacKinnon,K.; van Ham, C.; Reilly, K.; et al. Springer International Publishing (2019) CC

Biodiversity and healthy natural ecosystems, including protected areas in and around cities, provide ecosystem benefits and services that support human he..., including reducing flood risk, filtering air pollutants, and providing a reliable supply of clean drinking water. These services help to reduce the incidence of infectious diseases and respiratory disorders, and assist with adaptation to climate change. Access to nature offers many other direct health benefits, including opportunities for physical activity, reduction of developmental disorders and improved mental health. more

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The 2022 report of the Lancet Countdown on health and climate change: health at the mercy of fossil fuels
recommended

Romanello, M.; C. Di Napoli; P. Drummond, et al. The Lancet (2022) C1

The Lancet October 25, 2022DOI:https://doi.org/10.1016/S0140-6736(22)01540-9 As climate change’s impacts continue to accrue, countries are persistently making wrong choices that are harming human health.... A desperate global thirst for fossil fuels is worsening climate change, leading to more extreme weather events that have hit every continent, led to thousands of deaths, and caused $250+ billion in damage in 2021. • People 65+ and children <1 experienced 3.7 billion more heatwave days in 2021 than the annual average from 1986–2005. • Heat-related deaths shot up 68% from 2000–2004 to 2017–2021. • Climate change is abetting infectious disease transmission, warming coastal waters and leading to the spread of Vibrio bacteria like the one that causes cholera, and expanding the reach of the malaria parasite. more

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Children’s Palliative Care and Human Rights

Open Society Foundation (2015) C1

Palliative care for children with life-limiting illness is the active total care of the child’s body, mind, and spirit. It begins at diagnosis and continues regardless of whether the child receives treatment directed at the disease. It seeks to control all forms of suffering related to the illness... more

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Papua New Guinea Demographic and Health Survey 2016-18 Key Indicators Report

National Statistical Office Port Moresby, Papua New Guinea, The DHS Program (2019) C2

The DHS report itself explains the purpose was, “to obtain and provide information on basic indicators of social progress including fertility, childhood mortality, reproductive and child health, nutritional status of children, and awareness of HIV... more

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Vaccines are Not Enough: How Failure to Protect Human Rights compromised Chile’s COVID-19 response

International Commission of Jurists (2021) C2

To its credit, Chile has implemented a highly successful vaccine program and taken a number of other important public health measures to improve the well-being of its inhabitants. Nevertheless, these measures have proved insufficient to curb the ... more

National Monkeypox Public Health Response Guidelines

Federal Ministry of Health - Nigeria Centre for Disease Control (2019) CC

Since the re-emergence of monkeypox in Nigeria in September 2017, the Nigeria Centre for Disease Control(NCDC) has continued to receive reports and respond to cases of the disease from States across the country. Between September 2017 when the outbreak started and November 2018, about 300 suspecte... more

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New Drugs for Human African Trypanosomiasis: A Twenty First Century Success Story

Dickie, E.A.; Giordani, F.; Gould, M.K.; Mäser, P.; Burri, C.; Mottram, J.C.; Rao, S.P.S.; Barrett, M.P. MDPI Tropical Medicine and Infectious Disease (2020) CC2

The twentieth century ended with human African trypanosomiasis (HAT) epidemics raging across many parts of Africa. Resistance to existing drugs was emerging, and many programs aiming to contain the disease had ground to a halt, given previous succes... more

Praziquantel for the treatment of schistosomiasis during human pregnancy

Friedman, J.F. et al. (2018) CC

In 2014, an estimated 40 million women of reproductive age were infected with Schistosoma haematobium, S. japonicum and/or S. mansoni. In both 2003 and 2006, the World Health Organization (WHO) recommended that all schistosome-infected pregnant and ... more

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Current epidemiological evidence for predisposition to high or low intensity human helminth infection: a systematic review

Wright J.E., Werkman M., Dunn J.C. et al Parasites and Vectors (2018) C2

Background: The human helminth infections include ascariasis, trichuriasis, hookworm infections, schistosomiasis, lymphatic filariasis (LF) and onchocerciasis. It is estimated that almost 2 billion people worldwide are infected with helminths. Whils...t the WHO treatment guidelines for helminth infections are mostly aimed at controlling morbidity, there has been a recent shift with some countries moving towards goals of disease elimination through mass drug administration, especially for LF and onchocerciasis. However, as prevalence is driven lower, treating entire populations may no longer be the most efficient or cost-effective strategy. Instead, it may be beneficial to identify individuals or demographic groups who are persistently infected, often termed as being “predisposed” to infection, and target treatment at them. Methods: The authors searched Embase, MEDLINE, Global Health, and Web of Science for all English language, humanbased papers investigating predisposition to helminth infections published up to October 31st, 2017. The varying definitions used to describe predisposition, and the statistical tests used to determine its presence, are summarised. Evidence for predisposition is presented, stratified by helminth species, and risk factors for predisposition to infection are identified and discussed. Results: In total, 43 papers were identified, summarising results from 34 different studies in 23 countries. Consistent evidence of predisposition to infection with certain species of human helminth was identified. Children were regularly found to experience greater predisposition to Ascaris lumbricoides, Schistosoma mansoni and S. haematobium than adults. Females were found to be more predisposed to A. lumbricoides infection than were males. Household clustering of infection was identified for A. lumbricoides, T. trichiura and S. japonicum. Ascaris lumbricoides and T. trichiura also showed evidence of familial predisposition. Whilst strong evidence for predisposition to hookworm infection was identified, findings with regards to which groups were affected were considerably more varied than for other helminth species. Conclusion: This review has found consistent evidence of predisposition to heavy (and light) infection for certain human helminth species. However, further research is needed to identify reasons for the reported differences between demographic groups. Molecular epidemiological methods associated with whole genome sequencing to determine ‘who infects whom’ may shed more light on the factors generating predisposition. more

WASH and Infection Prevention and Control in Health Care Facilities

UN Children's Fund UNICEF (2020) C_UNICEF

This guidance note developed by UNICEF helps WASH staff in their preparedness and response to the current COVID-19 pandemic. It provides an overview of Infection Prevention and Control (IPC) and its intersection with water, sanitation and hygiene (WASH). It also provides key actions that staff can i... more

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Information Note: Disability and Inclusion in MHPSS - IASC Reference Group on Mental Health and Psychosocial Support in Emergency Settings (January 2024)

Inter-Agency Standing Committee (2024) C1

This document contains guidance for strengthening the disability inclusiveness of MHPSS responses and programmes in emergency settings. It is intended to supplement the IASC Guidelines on Mental Health and Psychosocial Support in Emergency Settings ... more

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Treatment options for second-stage gambiense human African trypanosomiasis

Eperon, G.; Balasegaram, M.; Potet, J.; Mowbray, C.; Valverde, O.; ois Chappui, F. Informa Healthcare (2014) CC

Treatment of second-stage gambiense human African trypanosomiasis relied on toxicarsenic-based derivatives for over 50 years. The availability and subsequent use of eflornithine,initially in monotherapy and more recently in combination with... more

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WASH FIT: A practical guide for improving quality of care through water, sanitation and hygiene in health care facilities (Second edition)

UN Children's Fund UNICEF; World Health Organization WHO (2023) C_WHO

Fully functioning water, sanitation, hygiene (WASH) and health care waste management services are a critical aspect of infection prevention and control (IPC) practices, and ensuring patient safety and quality of care. Such services are also essentia... more

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Promoting Cultural Diversity and Cultural Competency: Self-Assessment Checklist for Personnel Providing Services and Supports to Children with Disabilities & Special Health Needs and their Families

Tawara D. Goode (2018) CC

This checklist is intended to heighten the awareness and sensitivity of personnel to the importance of cultural diversity and cultural competence in human service settings. It provides concrete examples to demonstrate values and engage in practices ... more

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The new WHO guideline for control and elimination of human schistosomiasis: implications for the Schistosomiasis Elimination Programme in Nigeria

Akinola Stephen Oluwole, Uwem Friday Ekpo, Obiageli Josephine Nebe et al. Infectious Diseases of Poverty (2022) CC

With some 134,073,166 people living in endemic communities at risk of infection, Nigeria is the most endemic country in Africa and requires preventive chemotherapy (PC) for a total of 26.3 million persons. The National Schistosomiasis Elimination Programme (NSCHEP), with the support of international... more

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Elimination of Schistosomiasis Japonica in China: From the One Health Perspective

Zhong Hong, Lu Li, Lijuan Zhang et al. China CDC Weekly (2022) CC

The control of schistosomiasis was a high priority in China soon after the founding of the People’s Republic of China in 1949, and schistosomiasis japonica was largely brought under control through 7 decades of effort. However, great challenges still exist to completely eliminate schistosomiasis f... more

The Core Elements of Human Antibiotic Stewardship Programs in Resource-Limited Settings: National and Hospital Levels recommended

The 2022 report of the Lancet Countdown on health and climate change: health at the mercy of fossil fuels recommended

The Core Elements of Human Antibiotic Stewardship Programs in Resource-Limited Settings: National and Hospital Levels
recommended

The 2022 report of the Lancet Countdown on health and climate change: health at the mercy of fossil fuels
recommended