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Chronic obstructive pulmonary disease in sub-Saharan Africa

Awokola, B.I.; Amusa, G.A.; Jewell, C.P.; et al. International Journal of Tuberculosis and Lung Disease (2022) CC2

The article provides a systematic review and meta-analysis of the prevalence and risk factors of chronic obstructive pulmonary disease (COPD) in sub-Saharan Africa (SSA). It highlights that COPD is a significant cause of morbidity and mortality in the region, with prevalence rates ranging from 1.7% ... more

Chronic obstructive pulmonary disease in Brazilian primary care: diagnostic competence and case-ﬁnding

Hamers, R.; Bontemps, S.; van den Akker, M.; et al. Primary Care Respiratory Journal (2006) CC2

The article investigates the diagnostic capabilities and prevalence of chronic obstructive pulmonary disease (COPD) in primary care settings in northern Brazil. It highlights that COPD is often underdiagnosed and undertreated in resource-limited regions. The study involved 34 general practitioners a... more

Chronic obstructive pulmonary disease and associated healthcare resource consumption in the Middle East and North Africa: The BREATHE study

Polatli, M.; Kheder, A.B.; Wali, S.; et al. Respiratory Medicine (2012) CC2

The article examines the epidemiology of chronic obstructive pulmonary disease (COPD) in the Middle East, North Africa, and Turkey. It provides an overview of COPD prevalence, associated risk factors, and challenges in diagnosis and treatment across these regions. The study highlights smoking and en... more

Burden and risk factors of chronic obstructive pulmonary disease in Sub-Saharan African countries, 1990–2019: a systematic analysis for the Global Burden of disease study 2019

Alemayohu, M.A.; Zanolin, M.E.; Cazzoletti, L.; et al. eClinicalMedicine (2023) CC2

The article analyzes the prevalence and risk factors of chronic respiratory diseases, focusing on sub-Saharan Africa. It highlights that environmental exposures, such as biomass fuel usage and air pollution, significantly contribute to respiratory health issues in the region. The research underlines... more

An Estimate of the Prevalence of COPD in Africa: A Systematic Analysis

Adeloye, D.; Basquil, C.; Papana, A.; et al. COPD: Journal of Chronic Obstructive Pulmonary Disease (2014) CC2

The article provides a systematic analysis estimating the prevalence of Chronic Obstructive Pulmonary Disease (COPD) across Africa. It highlights the significant health burden COPD imposes on the continent, emphasizing varying prevalence rates influenced by factors such as tobacco smoking, exposure ... more

A systematic map and in-depth review of European telehealth interventions efficacy for chronic obstructive pulmonary disease

Gaveikaite, V.; Grunstrom, C.; Winter, S.; et al. Respiratory Medicine (2019) CC2

The article investigates the effectiveness and challenges of remote monitoring systems for chronic respiratory diseases, focusing on COPD and asthma. It reviews various technologies and their potential to improve patient outcomes through better symptom tracking, medication adherence, and early detec... more

Global, regional, and national prevalence of, and risk factors for, chronic obstructive pulmonary disease (COPD) in 2019: a systematic review and modelling analysis

Adeloye, D.; Song, P.; Zhu, Y. et al. (2022) CC2

Chronic obstructive pulmonary disease (COPD) is an increasingly important cause of morbidity, disability, and mortality worldwide. We aimed to estimate global, regional, and national COPD prevalence and risk factors to guide policy and population interventions.

Geographic distribution of COPD prevalence in the world displayed by Geographic Information System maps

Blanco, I.; Diego, I.; Bueno, P. et al. (2019) CC2

Existing data on chronic obstructive pulmonary disease (COPD) prevalence are irregularly distributed around the world, and in many geographic regions data are scarce or even nonexistent. This fact hinders the implementation of adequate preventive and therapeutic interventions to reduce the high burd... more

Barriers to childhood asthma care in sub-Saharan Africa: a multicountry qualitative study with children and their caregivers

Naidoo, K.L.; Dladla, S.; Mphahlele, R.E. et al. BMJ Open (2023) CC

This study identifies barriers and provides recommendations to improve asthma care in children across sub-Saharan Africa, where qualitative data is lacking despite high rates.

Does respiratory syncytial virus lower respiratory illness in early life cause recurrent wheeze of early childhood and asthma? Critical review of the evidence and guidance for future studies from a Wo

Driscoll, A.J.; Hasan Arshad, S.; Bont, L. et al. Vaccine (2020) CC

The article reviews the impact of respiratory syncytial virus (RSV) on global health, emphasizing its significant burden on infants, children, and the elderly. It discusses current and emerging prevention strategies, including the development and implementation of vaccines and monoclonal antibodies.... more

Building capacity to improve respiratory care: the education strategy of the International Primary Care Respiratory Group 2014–2020

McDonnell, J.; Corella de Sousa, J.; Baxter, N.; et al. npj Primary Care Respiratory Medicine (2014) CC2

The article discusses the education strategy of the International Primary Care Respiratory Group (IPCRG) for 2014–2020, focusing on building capacity to improve respiratory care globally. It highlights the significant burden of respiratory diseases and the role of primary care in addressing this i... more

The natural history of chronic obstructive pulmonary disease

Mannino, D.M.; Watt, G.; Hole, D.; et al. European Respiratory Journal (ERJ) (2006) CC2

The article from the European Respiratory Journal discusses the natural history of chronic obstructive pulmonary disease (COPD), emphasizing its increasing global impact on morbidity and mortality. It highlights that while cigarette smoking is a primary risk factor, other influences such as environm... more

Lung health in Africa: challenges and opportunities in the context of COVID-19

Ozho, O.B.; Mbatchou Ngahane, B.H.; Zar, H.J.; et al. American Journal of Physiology - Lung Cellular and Molecular Physiology (2021) CC2

The article discusses the challenges and opportunities for lung health in Africa in the context of the COVID-19 pandemic. It highlights the strain on healthcare systems, the increase in chronic respiratory diseases like asthma and COPD, and the limited resources for managing these conditions. The pa... more

Management of chronic obstructive pulmonary disease—A position statement of the South African Thoracic Society: 2019 update

Abdool-Gaffar, M. S.; Calligaro, G.; Wong, M.L. et al. Journal of Thoracic Disease (2019) CC2

The document outlines the 2019 update to the South African guideline for managing chronic obstructive pulmonary disease (COPD). It emphasizes the importance of early diagnosis, prevention through smoking cessation, use of bronchodilators as primary pharmacotherapy, and a comprehensive approach to pa... more

Rational Use of Inhaled Medications for the Patient with COPD and Multiple Comorbid Conditions: Guidance for Primary Care

Tisiligianni, I.; Hoines, K.; Jensen, C.; et al. International Primary Care Respiratory Group (IPCRG) (2019) CC2

The document discusses the complexities of managing patients with COPD and multiple comorbidities, highlighting the importance of personalized care and the appropriate use of inhaled corticosteroids (ICS). It outlines common comorbidities, such as asthma, osteoporosis, and diabetes, and offers guida... more

Appropriate use and withdrawal of inhaled corticosteroids (ICS) in patients with chronic obstructive pulmonary disease (COPD)

Román-Rodríguez, M.; Tsiligianni, I.; Wiliams, S.; et al. International Primary Care - Respiratory Group (2020) CC2

The document "Appropriate use and withdrawal of inhaled corticosteroids (ICS) in patients with chronic obstructive pulmonary disease (COPD)" from the IPCRG provides guidance on when to start, adjust, or discontinue ICS in COPD treatment. It highlights the benefits and risks, emphasizing personalized... more

Chronic Obstructive Pulmonary Disease (COPD) - Practice Essentials

Mosenifar, Z.; Brawerman, R.; Brawerman, G.; et al. Medscape (2024) CC2

The article provides a comprehensive overview of chronic obstructive pulmonary disease (COPD), covering its causes, symptoms, diagnostic methods, classification of severity, treatment options, and management strategies, with a focus on risk factors, clinical features, and therapeutic approaches such... more

Worldwide trends in the burden of asthma symptoms in school-aged children: Global Asthma Network Phase I cross-sectional study

Asher, I.; Rutter, C.E.; Bissell, K. et al. The Lancet (2021) CC

Asthma is the most common chronic disease in children globally. The Global Asthma Network (GAN) Phase I study aimed to determine if the worldwide burden of asthma symptoms is changing. This updated cross-sectional study used the same methods as the International study of Asthma and Allergies in Chi...ldhood (ISAAC) Phase III. Asthma symptoms were assessed from centres that completed GAN Phase I and ISAAC Phase I (1993–95), ISAAC Phase III (2001–03), or both. We included individuals from two age groups (children aged 6–7 years and adolescents aged 13–14 years) who self-completed written questionnaires at school. We estimated the 10-year rate of change in prevalence of current wheeze, severe asthma symptoms, ever having asthma, exercise wheeze, and night cough (defined by core questions in the questionnaire) for each centre, and we estimated trends across world regions and income levels using mixed-effects linear regression models with region and country income level as confounders. Overall, 119 795 participants from 27 centres in 14 countries were included: 74 361 adolescents (response rate 90%) and 45 434 children (response rate 79%). About one in ten individuals of both age groups had wheeze in the preceding year, of whom almost half had severe symptoms. Most centres showed a change in prevalence of 2 SE or more between ISAAC Phase III to GAN Phase I. Over the 27-year period (1993–2020), adolescents showed a significant decrease in percentage point prevalence per decade in severe asthma symptoms (–0·37, 95% CI –0·69 to –0·04) and an increase in ever having asthma (1·25, 0·67 to 1·83) and night cough (4·25, 3·06 to 5·44), which was also found in children (3·21, 1·80 to 4·62). The prevalence of current wheeze decreased in low-income countries (–1·37, –2·47 to –0·27], in children and –1·67, –2·70 to –0·64, in adolescents) and increased in lower-middle-income countries (1·99, 0·33 to 3·66, in children and 1·69, 0·13 to 3·25, in adolescents), but it was stable in upper-middle-income and high-income countries. Trends in prevalence and severity of asthma symptoms over the past three decades varied by age group, country income, region, and centre. The high worldwide burden of severe asthma symptoms would be mitigated by enabling access to effective therapies for asthma. more

The increasing burden of asthma in South African children: A call to action

Masekela, R.; Gray, C.L.; Green, R.J. et al. The South African Medical Journal (2018) CC

BACKGROUND. Asthma is a heterogeneous condition characterised by chronic inflammation and variable expiratory airflow limitation, as well as airway reversibility. The burden of asthma in children is increasing in low- and middle-income countries and remains under-recognised and poorly managed. OBJE... more

Symptom-based screening tool for asthma syndrome among young children in Uganda

Nantanda, R.; Siersma, V.; Ndeezi, G. et al. npj Primary Care Respiratory Medicine (2020) CC

Under-diagnosis of asthma in ‘under-fives’ may be alleviated by improved inquiry into disease history. We assessed a questionnaire-based screening tool for asthma among 614 ‘under-fives’ with severe respiratory illness in Uganda. The questionnaire responses were compared to post hoc consensu... more