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INDEX-TB GUIDELINES: Evidence Summaries and Guideline Panel Decision Tables Core Group Guideline Meeting

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This document contains: The systematic reviews and GRADE assessments used at the Index-TB Guideline Panel in July 2015; The Evidence to Decision tables that record the Panel’s assessment and recommendations from this meeting
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Long-acting injectable vs oral antipsychotics for relapse prevention in schizophrenia: a meta-analysis of randomized trials

Kishimoto T., Robenzadeh A, Leucht C, et al. (2014) CC
Schizophr Bull. 2014 Jan;40(1):192-213. doi: 10.1093/schbul/sbs150. Epub 2012 Dec 17.
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This Review summarizes many of the persistent biological alterations associated with childhood maltreatment including changes in neuroendocrine and neurotransmitter systems and pro-inflammatory cytokines in addition to specific alterations in brain areas associated with mood regulation. Finally, I d... more
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Conventional and and atypical antipsychotics & antidepressant (trazodone) for behavioural and psychological symptoms in people with dementia

World Health Organization (2012) C_WHO
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EPI 4: Antiepileptic medications for adults and children with HIV

World Health Organization WHO (2015) C_WHO
Scoping Question: For adults and children living with HIV, which antiepileptic medications (such as phenobarbital, phenytoin, carbamazepine or valproic acid) produce benefits and/or harms when compared to a placebo or controls?
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Standard antiepileptic drugs (phenobarbital, phenytoin, carbamazepine, valproic acid) for management of convulsive epilepsy in adults and children

World Health Organization (2012) C_WHO
Q 7: For adults and children with convulsive epilepsy, which standard antiepileptic drugs (phenobarbital, phenytoin, carbamazepine, valproic acid) when compared to placebo/a comparator produce benefits/harm in the specified outcomes?
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EPI 1: Antiepileptic medications for management of acute convulsive seizures when no intravenous access is available

World Health Organization WHO (2015) C_WHO
[Updated 2015] Scoping Question: In adults with acute convulsive seizures in first-level care or in the community (when no IV access is available), which antiepileptic medications produce benefits and/or harm when compared to comparator?
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EPI 5: Anti-epileptic medicines for medication resistant convulsive epilepsy. [New 2015]

mhGAP; WHO (2015) C_WHO
SCOPING QUESTION: For adults and children with medication-resistant convulsive epilepsy, which anti-epileptic medications produce benefits and/or harm in the specified outcomes when compared to a placebo or a comparator?
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Separation Anxiety

A. Figueroa; C. Soutullo; Y. Ono; et al. IACAPAP (2012) C2
Anxiety disorders Chapter F.2
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Pharmacological interventions for anxiety disorders in children and adolescents

World Health Organization WHO World Health Organization (2012) C_WHO
Q 12: In children and adolescents with anxiety disorders, what is the effectiveness and safety, considering system issues in low- and middle-income countries, of using pharmacological interventions in non-specialist settings?
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Antidepressants (Tricyclic Antidepressants, Selective Serotonin Reuptake Inhibitors) in children 6-12 years of age with depressive episode/disorder

World Health Organization (2012) C_WHO
Q10: Are antidepressants (Tricyclic antidepressants (TCA), Selective serotonin reuptake inhibitors (SSRIs)) effective and safe in children 6-12 years of age with depressive episode/disorder?
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Treatment of anxiety disorders

B.Bandelo, S. Michaelis, D. Wedekind (2017) CC
Dialogues Clin Neurosci. 2017 Jun; 19(2): 93–107.
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Comparative effectiveness of different formats of psychological treatments for depressive disorder
recommended

World Health Organization WHO WHO (2015) C_WHO
Q8.SCOPING QUESTION: In adults and older adolescents with depressive disorder, what is the comparative effectiveness of different formats of psychological treatments?
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Physical Activity

World Health Organization WHO (2012) C_WHO
Q6: Is advice on physical activity better (more effective than/as safe as) than treatment as usual in adults with depressive episode/disorder with inactive lifestyles
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Mental health problems in people with learning disabilities overview

National Institute for Health and Care Excellence (NICE) (2018) C2
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Second-generation antipsychotic medications for psychotic disorders (including schizophrenia)
recommended

World Health Organization WHO (2012) C_WHO
Q14. SCOPING QUESTION: In adults with psychotic disorders (including schizophrenia), what is the comparative effectiveness and safety of second-generation antipsychotic medications?
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Why urban health matters

World Health Organization WHO; 1000 Cities 1000 Lives (2010) C_WHO
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South African National TB Guidelines - Children

Medicines Information Centre; SPES Bona; National HIV & TB Health Care Worker Hotline (2019) C2
Accessed: 08.10.2019 Based on the National Guidelines for the Management of Tuberculosis in Children 2013, Department of Health, South Africa.
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Weekends-off efavirenz-based antiretroviral therapy in HIV-infected children, adolescents and young adults (BREATHER): Extended follow-up results of a randomised, open-label, non-inferiority trial

A. Turkova; C. L. Moore; K. Butler; et al. PLOS One; Pub Med (2018) CC
PLOS ONE | https://doi.org/10.1371/journal.pone.0196239 April 23, 2018
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Childhood Tuberculosis: Diagnosis, Treatment and Prevention of TB in HIV-infected Children

C. DC Christie-Samuels World Health Organization (2019) C_WHO
Accessed: 21.10.2019