Cryptococcal disease is one of the most common opportunistic infections among people living with advanced HIV disease and is a major contributor to severe illness, morbidity, and mortality, particularly in sub-Saharan Africa.
These guidelines update the recommendations that were first released i...n 2018 on diagnosing, preventing, and managing cryptococcal disease. In response to important new evidence that became available in 2021, these new guidelines strongly recommend a single high dose of liposomal amphotericin B as part of the preferred induction regimen for the treatment of cryptococcal meningitis in people living with HIV. This simplified regimen - a single high dose of liposomal amphotericin B paired with other standard medicines (flucytosine and fluconazole) - is as effective as the previous WHO standard of care, with the benefits of lower toxicity and fewer monitoring demands.
The objective of these guidelines is to provide updated, evidence-informed recommendations for treating adults, adolescents and children living with HIV who have cryptococcal disease. These guidelines are aimed at HIV programme managers, policymakers, national treatment advisory boards, implementing partners and health-care professionals providing care for people living with HIV in resource-limited settings with a high burden of cryptococcal disease.
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2018 monitoring report: current status and strategic priorities
The report sets out the status of women’s, children’s and adolescents’ health, and on health systems and social and environmental determinants. Regional dashboards on 16 key ...indicators highlight where progress is being made or lagging. There is progress overall, but not at the level required to achieve the 2030 goals. There are some areas where progress has stalled or is reversing, namely neonatal mortality, gender inequalities and health in humanitarian settings.
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The State of the World's Midwifery
Objective: This study examined the experiential factors and interacting vulnerabilities that contribute to the development of posttraumatic stress disorder (PTSD) in children and adolescents
Am J Psychiatry 2000; 157:1229–1235)
Background: Traumatic stress may arise from various incidents often leading to posttraumatic stress disorder (PTSD). The lifetime prevalence of PTSD is estimated at 1% – 2% in Western Europe, 6% – 9% in North America and at just over 10% in countries exposed to long-term
violence. In South Afri...ca, the lifetime prevalence for PTSD in the general population is estimated at 2.3%.
Aim: To examine the prevalence of posttraumatic stress symptomatology and related psychological functioning in a community sample of adolescents.
Setting: Low-socioeconomic communities in KwaZulu-Natal.
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Post-Traumatic Stress Disorder (PTSD) in Children under Age 6 | Post-Traumatic Stress Disorder (PTSD) in Children and Adolescents Ages 6 to 17 Years Old
Accessed January 22, 2019.
This updated version include important research that has added to our knowledge about effective treatments for
child and adolescent depression. Its goal is to help parents and families make informed decisions about gett...ing the best care for a child with depression. For easy use, it is presented in Frequently Asked Questions (FAQ) format.
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This guide provides an overview of important points to consider in the assessment and treatment of PTSD and ASD in children and adolescents. The practitioner checklist later in this document can help
to guide assessment and treatment planning.
Purpose of review: We review recent evidence regarding risk factors for childhood posttraumatic stress disorder (PTSD) and treatment outcome studies from 2010 to 2012 including dissemination studies, early intervention studies and studies involving preschool children.
Background: Several studies have demonstrated that South African children and adolescents are
exposed to high levels of violent trauma with a significant proportion developing PTSD, however,
limited resources make it difficult to accurately identi...fy traumatized children.
Conclusions: Our results indicate that trauma exposure and PTSD are prevalent in South African
youth and if appropriate cut-offs are used, self-report scales may be useful screening tools for
PTSD.
Annals of General Psychiatry 2005, 4:2doi:10.1186/1744-859X-4-2
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Q9: What is/are the effective and safe interventions to treat somatoform disorders in children and adolescents in non- specialist health settings?
This report presents the most current data on four specific forms of violence – violent discipline and exposure to domestic abuse during early childhood; violence at school; violent deaths among adolescents; and sexual violence in childhood and ...pan class="attribute-to-highlight medbox">adolescence. The statistics reveal that children experience violence across all stages of childhood, in diverse settings, and often at the hands of the trusted individuals with whom they interact daily. The report concludes with specific national actions and strategies that UNICEF has embraced to prevent and respond to violence against children.
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Olashore et al.
Child Adolesc Psychiatry Ment Health (2017) 11:8 DOI 10.1186/s13034-017-0144-9
D’un format facilement accessible, simple à utiliser, le présent document décrit succinctement
les problèmes liés à la santé et aux droits en matière de sexualité et de reproduction qui peuvent
affecter les droits fondamentaux, la santé et le bien-être des ...ghlight medbox">adolescents (âgés de 10 à 19 ans)
et il présente les lignes directrices pertinentes de l’Organisation mondiale de la Santé (OMS). Ce
document donne accès aux nombreuses lignes directrices formulées par l’OMS, et il constitue
une source d’informations utile pour les activités de sensibilisation, la conception des politiques
et des programmes ou projets et la recherche. Son objectif est de soutenir la mise en oeuvre
de la stratégie mondiale pour la santé des femmes, des enfants et des adolescents 2016–2030 (1), en conformité avec le cadre pour une action mondiale accélérée en faveur de la santé des
adolescents et avec le cadre opérationnel de l’OMS sur la santé sexuelle et ses liens avec la
santé reproductive (2,3).
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Programme Brief
Accessed: 21.08.2019
Journal of Child Psychology and Psychiatry60:5 (2019), pp 500–515