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Meningitis Outbreak Response in Sub-Saharan Africa

Christina Brandes-Barbier, Véronique Millot, Tomas Allen et al World Health Organization WHO (2014) C_WHO

WHO Guideline. Since 2010, countries in the meningitis belt have started to introduce a new serogroup A meningococcal conjugate vaccine conferring individual protection and herd immunity. Following the successful roll-out of this vaccine, epidemics due to Neisseria meningitidis serogroup A (NmA) are... more

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Recovery-oriented strategies enhancing vocational and economic inclusion (such as supported employment)

World Health Organization WHO (2015) C_WHO

Q12. SCOPING QUESTION: In people with psychotic disorders, including schizophrenia and bipolar disorder, are recovery-oriented strategies enhancing vocational and economic inclusion (such as supported employment) feasible and effective?

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Snakebite envenoming -- A strategy for prevention and control

World Health Organization WHO (2019) C_WHO

The core of the strategy is the goal for all patients to have better overall care, so that the numbers of deaths and cases of disability are reduced by 50% before 2030. For this to be achieved, four strategic aims will be pursued. Empower and engage communities, Ensure safe, effective tre... more

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Trichiasis surgery for trachoma Second Edition

Merbs, S.; Resnikoff, S.; Kello, A. World Health Organization WHO (2015) C_WHO

This manual is designed to provide specific information for trachomatous trichiasis (TT) trainers who are training others to undertake surgery for entropion trachomatous trichiasis (TT). Other approaches are not addressed. The manual is divided into two parts. The first part covers specifics designe... more

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Therapeutics and COVID-19 (Living Guideline, 10 November 2023)

World Health Organization WHO (2023) C_WHO

WHO has updated its guidelines for COVID-19 therapeutics, with revised recommendations for patients with non-severe COVID-19. This is the 13th update to these guidelines. Updated risk rates for hospital admission in patients with non-severe COVID-19 The guidance includes updated risk rates for... hospital admission in patients with non-severe COVID-19. The current COVID-19 virus variants tend to cause less severe disease while immunity levels are higher due to vaccination, leading to lower risks of severe illness and death for most patients. This update includes new baseline risk estimates for hospital admission in patients with non-severe COVID-19. The new ‘moderate risk’ category now includes people previously considered to be high risk including older people and/or those with chronic conditions, disabilities, and comorbidities of chronic disease. The updated risk estimates will assist healthcare professionals to identify individuals at high, moderate or low risk of hospital admission, and to tailor treatment according to WHO guidelines: **High: **People who are immunosuppressed remain at higher risk if they contract COVID-19, with an estimated hospitalization rate of 6%. **Moderate: **People over 65 years old, those with conditions like obesity, diabetes and/or chronic conditions including chronic obstructive pulmonary disease, kidney or liver disease, cancer, people with disabilities and those with comorbidities of chronic disease are at moderate risk, with an estimated hospitalization rate of 3%. Low: Those who are not in the high or moderate risk categories are at low risk of hospitalization (0.5%). Most people are low risk. Review of COVID-19 treatments for people with non-severe COVID-19 WHO continues to strongly recommend nirmatrelvir-ritonavir (also known by its brand name ‘Paxlovid’) for people at high-risk and moderate risk of hospitalization. The recommendations state that nirmatrelvir-ritonavir is considered the best choice for most eligible patients, given its therapeutic benefits, ease of administration and fewer concerns about potential harms. Nirmatrelvir-ritonavir was first recommended by WHO in April 2022. If nirmatrelvir-ritonavir is not available to patients at high-risk of hospitalization, WHO suggests the use of molnupiravir or remdesivir instead. WHO suggests against the use of molnupiravir and remdesivir for patients at moderate risk, judging the potential harms to outweigh the limited benefits in patients at moderate risk of hospital admission. For people at low risk of hospitalization, WHO does not recommend any antiviral therapy. Symptoms like fever and pain can continue to be managed with analgesics like paracetamol. WHO also recommends against use of a new antiviral (VV116) for patients, except in clinical trials. The update also includes a strong recommendation against the use of ivermectin for patients with non-severe COVID-19. WHO continues to advise that in patients with severe or critical COVID-19, ivermectin should only be used in clinical trials. more

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Strategy to respond to antimalarial drug resistance in Africa

World Health Organization WHO (2022) C_WHO

The Strategy to respond to antimalarial drug resistance in Africa is a technical and advocacy document, grounded in the best available evidence to date and aimed at minimizing the threat and impact of antimalarial drug resistance of Plasmodium falciparum parasites in Africa. Its objectives are to: i... more

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Burden of disease attributable to unsafe drinking-water, sanitation and hygiene: 2019 update

World Health Organisation (WHO) (2023) C_WHO

The report summarizes the estimates of the burden of disease attributable to unsafe drinking water, sanitation, and hygiene for the year 2019 for four health outcomes - diarrhoea, acute respiratory infections, soil-transmitted helminthiases, and undernutrition - which are included in the reporting o... more

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Preventing suicide: A community engagement toolkit
recommended

World Health Organization WHO (2018) C_WHO

Suicides take a high toll. Over 800 000 people die by suicide every year and it is the second leading cause of death in 15-29-year-olds. Most suicides occur in low- and middle-income countries where resources and services, if they do exist, are often scarce and limited for early identification, tr... more

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Consolidated HIV guidelines for prevention, treatment, service delivery & monitoring
recommended

World Health Organization WHO (2021) CC

July 2021. This publication brings together important clinical and programmatic updates produced by WHO since 2016 and provides comprehensive, evidence-informed recommendations and good practice statements within a public health, rights-based and person-centred approach. These guidelines bring in... more

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Ending the neglect to attain the sustainable development goals. One health: approach for action against neglected tropical diseases 2021-2030

World Health Organization WHO (2021) C_WHO

This companion document to Ending the neglect to attain the Sustainable Development Goals: a road map for neglected tropical diseases 2021-2030 ("the road map") aims to support a range of stakeholders - including countries in which neglected tropical diseases (NTDs) are endemic, international organi... more

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Alternative drinking-water disinfectants: Bromine, iodine and silver

World Health Organization (WHO) (2018) CC

Disinfection of drinking-water supplies has been one of the most significant public health advancements of the last century with respect to reducing waterborne disease.
Although chlorine has been used as the disinfectant of choice for public drinking-water supplies for the past century, a numbe... more

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People-centred framework for tuberculosis programme planning and prioritization, User guide

World Health Organization WHO (2019) C_WHO

The aim of the people-centred framework is to help countries to develop fully prioritized and budgeted NSPs based on a culture of making full use of the available data, which are aligned with national planning cycles and which provide the basis for a robust national response that can accelerate prog... more

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Public–private mix for TB prevention and care: a roadmap

World Health Organization WHO (2018) C_WHO

In 2017, 3.6 million of the estimated 10 million people with TB worldwide were “missed” by national TB programmes (NTPs). Two thirds of them are thought to access TB treatment of questionable quality from public and private providers who are not engaged by the NTP. The quality of care provided i... more

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Generic risk assessment model for insecticide-treated nets, 2nd ed.

World Health Organization (WHO) (2018) C_WHO

Long-lasting insecticidal nets (LNs) constitute a core vector control intervention against malaria. A number of new LN products are under development and will require assessment of risks to humans. This document provides an updated generic model that can be used for the risk assessment of exposure t... more

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Generic risk assessment model for indoor residual spraying of insecticides, 2nd ed.

World Health Organization (WHO) (2018) C_WHO

This document provides a generic model that can be used for risk assessment of exposure to insecticide products applied as indoor residual sprays. It aims to harmonize the risk assessment of such insecticides for public health use in order to generate comparable data for their registering and labell... more

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Guidelines for the management of pregnant and breastfeeding women in the context of Ebola virus disease
recommended

World Health Organization WHO (2020) C1

To save the lives of mothers and their babies, mitigate complications, and limit the spread of disease, it is critical that recommendations are made on the prevention, treatment, and surveillance of women who are exposed to EVD, acquire EVD during pregnancy or breastfeeding, or survive EVD with ongo... more

Preventing suicide: A community engagement toolkit recommended

Consolidated HIV guidelines for prevention, treatment, service delivery & monitoring recommended

Guidelines for the management of pregnant and breastfeeding women in the context of Ebola virus disease recommended

Preventing suicide: A community engagement toolkit
recommended

Consolidated HIV guidelines for prevention, treatment, service delivery & monitoring
recommended

Guidelines for the management of pregnant and breastfeeding women in the context of Ebola virus disease
recommended