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1
Cryptococcal disease is one of the most common opportunistic infections among people living with advanced HIV disease and is a major contributor to severe illness, morbidity, and mortality, particularly in sub-Saharan Africa.
These guidelines update the recommendations that were first released i
...
n 2018 on diagnosing, preventing, and managing cryptococcal disease. In response to important new evidence that became available in 2021, these new guidelines strongly recommend a single high dose of liposomal amphotericin B as part of the preferred induction regimen for the treatment of cryptococcal meningitis in people living with HIV. This simplified regimen - a single high dose of liposomal amphotericin B paired with other standard medicines (flucytosine and fluconazole) - is as effective as the previous WHO standard of care, with the benefits of lower toxicity and fewer monitoring demands.
The objective of these guidelines is to provide updated, evidence-informed recommendations for treating adults, adolescents and children living with HIV who have cryptococcal disease. These guidelines are aimed at HIV programme managers, policymakers, national treatment advisory boards, implementing partners and health-care professionals providing care for people living with HIV in resource-limited settings with a high burden of cryptococcal disease.
more
The goal of this Global Action Plan is to articulate synergistic actions that will be required to prevent HIVDR from undermining efforts to achieve global targets on health and HIV, and to provide the most effective treatment to all people living with HIV including adults, key populations, pregnant
...
and breastfeeding women, children and adolescents. The Global Action Plan has five strategic objectives: 1) prevention and response; 2) monitoring and surveillance; 3) research and innovation; 4) laboratory capacity; and 5) governance and enabling mechanisms.
more
The HIV drug resistance report 2021 summarizes findings from 38 countries that had finalized the surveys by the time of this report and shared data with WHO.
Pretreatment HIVDR to non-nucleoside reverse-transcriptase inhibitors (NNRTI) can affect more than 10% of adults starting therapy and is fo
...
und up to 3 times more often in people who had previous exposure to antiretroviral drugs. In addition, nearly half of infants newly diagnosed with HIV has HIVDR to NNRTI before initiating treatment.The high levels of observed NNRTI pretreatment HIVDR among emphasize the need to fast-track the transition to WHO-recommended dolutegravir-based ART.
more
Tips for Engaging Communities during COVID-19 in Low-Resource Settings, Remotely and In-Person
recommended
This brief provides key considerations for engaging communities on COVID-19 and tips for how to engage where there are movement restrictions and physical distancing measures in place, particularly in low-resource settings.
2018
Vol.5 No.2:73
DOI: 10.21767/2254-9137.100092
Health Systems and Policy Research ISSN 2254-9137
An 82 percent funding gap is putting the lives of 2.5 million people in north-west Syria at risk this winter.
The first cholera case in north-west Syria was confirmed on 19 September. See below for the latest updates.
On 17 September, at least six airstrikes were reported in Idleb, 10
...
km away from the road used by the 7th cross-line convoy. One man was injured.
On 27 September, an airstrike reportedly hit in the vicinity of five IDP camps in Idleb, near the Bab AlHawa border crossing, injuring a woman, child and seven men.
HNAP recorded 19,545 new internal displacements in north-west Syria in September – the highest record so far in 2022 - largely driven by the deteriorating economy.
more
Technical guidance.
This technical guidance aims to inform policy and practice development specifically related to improving the health of older refugees and migrants within the European Union and the larger WHO European Region. Both ageing and migration are in themselves complex multidimensional p
...
rocesses shaped by a range of factors at the micro, meso and macro levels over the life-course of the individual, but also with intertwined trajectories. Relevant areas for policy-making include healthy ageing over the life-course, supportive environments, people-centred health and long-term care services, and strengthening the evidence base and research
more
Nutrition training of health and agriculture workers can help to reduce child undernutrition. Specifically, trained health extension workers cancontribute through frequent nutrition counselling of caregivers. Evidence from systematic reviews has showed that providing nutrition training targeting hea
...
lth workers can improve feeding frequency, energy intake, and dietary diversity of children aged six months to two years. Scaling up of nutrition training for health and agriculture workers presents a potential entry point to improve nutrition status among childrenFood insecurity and nutrition deficiency are a common phenomenon in Ethiopia.
more
Toolkit for research and development of paediatric antiretroviral drugs and formulations
World Health Organization (WHO); Unitaid; Unicef; et al.
World Health Organization (WHO); Unitaid; Unicef; et al.
(2018)
C_WHO
WHO and UNITAID
in collaboration with IMPAACT (International Maternal Pediatric Adolescent AIDS Clinical Trials) network, PENTA (Paediatric European Network for Treatment of AIDS) foundation and experts from the Paediatric Antiretroviral Working Group
Rapport biennal de la directrice régionale
Disability-inclusive social protection research in Nepal
Banks, Lena M., Walsham, Matthew and others
International Centre for Evidence in Disability
(2018)
C1
A national overview with a case study from Tanahun district. The overall aims of this study are (1) to assess the extent to which social protection systems in Nepal address the needs of people with disabilities; and (2) to identify and document elements of good practice, as well as challenges, in th
...
e design and delivery of social protection for people with disabilities. As most social protection programmes in Nepal are targeted to various groups considered to be a high risk of poverty or marginalisation (e.g. orphans, widows), the research mainly focuses on disability-specific schemes, as they are relevant to a higher proportion of people with disabilities.
more
Disability-inclusive social protection research in Vietnam
Banks, Lena M., Walsham, Matthew and others
International Centre for Evidence in Disability
(2018)
C1
A national overview with a case study from Cam Le district
The overall aims of this study are (1) to assess the extent to which social protection systems in Vietnam address the needs of people with disabilities; and (2) to identify and document elements of good practice, as well as challenges, ... in the design and delivery of social protection for people with disabilities. As most social protection programmes in Vietnam are targeted to various vulnerable groups (e.g. orphans, widows, single parents), the research mainly focuses on disability-specific schemes, as they are relevant to a higher proportion of people with disabilities. more
The overall aims of this study are (1) to assess the extent to which social protection systems in Vietnam address the needs of people with disabilities; and (2) to identify and document elements of good practice, as well as challenges, ... in the design and delivery of social protection for people with disabilities. As most social protection programmes in Vietnam are targeted to various vulnerable groups (e.g. orphans, widows, single parents), the research mainly focuses on disability-specific schemes, as they are relevant to a higher proportion of people with disabilities. more
Le présent rapport annuel 2016 met en exergue la contribution du Bureau de la Représentation de l’OMS aux efforts de santé du gouvernement du Niger. Il porte sur l’état de réalisation des activités planifiées dans le plan de travail biennal 2016-2017 entre l’OMS et le Ministère de la S
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anté Publique. Les activités réalisées ont pu aboutir grâce à une étroite collaboration établie entre les équipes techniques du bureau de l’OMS et du Ministère de la Santé ainsi qu’avec les partenaires au secteur de la santé.
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La question des effets du changement climatique sur les hommes et les femmes a été définie par la Commission de la condition de la femme comme une de celles qui doivent davantage retenir l’attention. Les normes, rôles et relations relatifs au genre (voir l’Encadré 1) sont d’importants fac
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teurs déterminant la vulnérabilité et la capacité d’adaptation aux effets du changement climatique sur la santé (voir l’Encadré 2). Les femmes et les hommes sont vulnérables face aux effets des événements climatiques extrêmes non seulement du point de vue biologique, mais aussi du fait de leurs rôles et responsabilités sociaux distincts (Easterling, 2000 ; Wisner et al., 2004) qui peuvent varier mais se retrouvent dans toutes les sociétés. Les femmes doivent souvent supporter des charges supplémentaires en cas d’événements climatiques extrêmes du fait des rôles et responsabilités qu’elles sont censées assumer en s’occupant de la famille, alors que les hommes de leur côté supporteront des charges supplémentaires du fait de leur rôle économique.
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Commissioned by Plan International the report draws on data from research conducted in Bangladesh in April 2018. It explores how adolescent girls within two age brackets (10-14 and 15-19) understand the unique impact the crisis has upon them, and how they have responded to the challenges they face.
... Despite the numbers of adolescent girls affected so profoundly by the ongoing Rohingya crisis, and of course, by many crises around the world, it is rare that either their own communities or the humanitarian sector at large pay much attention to them. This research is an attempt to rectify that: to acknowledge that girls and young women do have rights and that their ideas are worth listening to and acting upon.
Among the many learnings, we discovered that girls feel isolated. They have settled among strangers, and parents worry about their safety, keeping them even more trapped inside their new, makeshift homes.
75% of girls interviewed said they have no ability to make decisions about their own lives. more
... Despite the numbers of adolescent girls affected so profoundly by the ongoing Rohingya crisis, and of course, by many crises around the world, it is rare that either their own communities or the humanitarian sector at large pay much attention to them. This research is an attempt to rectify that: to acknowledge that girls and young women do have rights and that their ideas are worth listening to and acting upon.
Among the many learnings, we discovered that girls feel isolated. They have settled among strangers, and parents worry about their safety, keeping them even more trapped inside their new, makeshift homes.
75% of girls interviewed said they have no ability to make decisions about their own lives. more
In the last 5 years, the conflict in South Sudan has displaced 4 million people and placed 7 million in need of humanitarian assistance.
This report commissioned by Plan International draws on research conducted with girls and members of their families and communities in multiple sites in South ... Sudan and Uganda.
It explores how adolescent girls within two age brackets (aged 10-14 and 15-19) understand and respond to the unique impact their country’s crisis has upon them.
It seeks to amplify their voices and their perceptions of the crisis and presents their views on how the humanitarian sector might respond. more
This report commissioned by Plan International draws on research conducted with girls and members of their families and communities in multiple sites in South ... Sudan and Uganda.
It explores how adolescent girls within two age brackets (aged 10-14 and 15-19) understand and respond to the unique impact their country’s crisis has upon them.
It seeks to amplify their voices and their perceptions of the crisis and presents their views on how the humanitarian sector might respond. more