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Lancet 2021; 398: Series: Heat and Health Hot weather and heat extremes harm human health, with poverty, ageing, and chronic illnesses as aggravating factors. As the global community contends with even hotter weather in a changing climate, there is a pressing need to better understand the most eff... more
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Viral hepatitis is defined as inflammation of the liver cells due to viral infection. The burden of liver disease in South Africa is mostly underestimated as viral hepatitis, in particular chronic infection, is a silent and neglected cause of morbidity and .... However, the burden of disease is likely substantial given the prevalence of chronic viral hepatitis. This burden is further compounded by the lack of screening and access to care and treatment as well as inadequate disease surveillance, human and financial resources. The National Guidelines for the Management of Viral Hepatitis were developed, with the purpose to: inform healthcare workers in the public and private sectors about the disease, its epidemiology in South Africa and current methods of diagnosis and therapy strengthen the healthcare response to viral hepatitis empower communicable diseases workers and stakeholders to make informed decisions regarding appropriate and cost effective interventions more

Cancer in sub-Saharan Africa

Ngwa, W.; et al. Lancet Oncology Commission (2022) C2
Lancet Oncol 2022; 23: e251–312Published OnlineMay 9, 2022 https://doi.org/10.1016/S1470-2045(21)00720-8 In sub-Saharan Africa (SSA), urgent action is needed to curb a growing crisis in cancer incidence and mortality. Without rapid interventions... more
This is the first edition of Empiric Antibiotic Guidelines, as a guidance to all medical practitioners at North Okklapa General & Teaching Hospital. Antibiotics are critical in the management of infection and can have a significant impact in reducing morbidity and .... Emerging antimicrobial resistance has been identified as global challenge by the World Health Organization. Careful use of antibiotics targeted to likely pathogens is an important strategy in combating development of antimicrobial resistance. more
J Bras Pneumol. 2022;48(2):e20220082 The spread of Severe Acute Respiratory Syndrome - Coronavirus 2 (SARS-CoV-2) continues to progress, causing damage in several countries of the world due to its rapid transmissibility and significant mortality ra... more
The World Health Organization (WHO) recognizes the challenges countries face for maintaining their COVID-19 response while addressing competing public health challenges, conflicts, climate change and economic crises. It remains critical for national programmes to continue to offer testing for COVI... more
Lancet Public Health 2022 Published Online October 25, 2022 https://doi.org/10.1016/S2468-2667(22)00197-9 Executive summary In the past few decades, major public health advances have happened in Europe, with drastic decreases in premature mortality... more
Last accessed on 21.12.22 IPCHS is a new concept for Zambia and has been implemented in limited proportions. The WHO global strategy on IPCHS reported that in Zambia there is limited focus on integrated community case management for malaria, pneumonia and diarrhoea to reduce child .... The Ministry of Health (MoH) in Zambia aims at attaining Universal Health Coverage in which all Zambians have access to essential health services. But, despite the Zambian health sector implementing the Sexual Reproductive, Maternal, Newborn, Child Adolescent and Nutrition (SRMNCAH&N) services, the sector continues to face challenges and needs to continue devising solutions to address them. more
Research and Reports in Tropical Medicine 2022:13 25–40 Chagas disease (CD) or American trypanosomiasis is a neglected parasitic disease associated with significant mortality and morbidity that includes long-term disability, social stigma and a m... more

Dengue epidemiology

Jing, Q.; Wang, M. Global Health Journal (2019) CC
Dengue is the fastest spreading, mosquito-borne viral infectious disease worldwide, with remarkable morbidity and mortality. In the past decades, profound contributions have been made towards understanding its epidemiology, including disease burden ... more
DNA studies of Egyptian mummies shows evidence of the existence of Schistosomiasis about 5000 years ago. Schistosomiasis is increasing in prevalence, affecting nearly 10% of the world’s population and ranking second only to malaria as a cause of morbidity & .... Schistosoma haematobium are found in tropical Africa & part of southwest Asia. Schistosoma mansoni are found in tropical Africa, part of southwest Asia, south America & Caribbean islands. Schistosoma japonicum are found in parts of Japan, China, Philippines, India & part of southeast Asia. Blood flukes are known as schistosomes because of the "split body" on the ventral side of the male, in which the female is held during insemination and egg laying. Man is the definite host harbouring adult parasites, and fresh water snails are intermediate hosts. more
Breast cancer is the most common cancer worldwide and the leading cause of cancer deaths among women, disproportionately affecting low- and middle-income countries. The Global Breast Cancer Initiative strives to reduce breast cancer mortality by 2.5... more
Research and Reports in Tropical Medicine 2022:13 25–40. Chagas disease (CD) is caused by the parasite Trypanosoma cruzi, and it is endemic in Central, South America, Mexico and the South of the United States. It is an important cause of early mortality... and morbidity, and it is associated with poverty and stigma. A third of the cases evolve into chronic cardiomyopathy and gastrointestinal disease. This review proposes strategies to address challenges faced by non-endemic countries more
Snake-bites are well-known medical emergencies in many parts of the world, especially in rural areas. Agricultural workers and children are the most affected. The incidence of snake-bite mortality is particularly high in South-East Asia. Rational us... more
Since 2002 the distribution of external funding to reproductive, maternal, newborn, and child health (RMNCH) has become more equitable and better targeted at the poorest countries and those experiencing the highest mortality. The aid envelope is not... more
Background: The last decade has seen a dramatic increase in international and domestic funding for malaria control, coupled with important declines in malaria incidence and mortality in some regions of the world. As the ongoing climate of financial ... more
Background: In 2015, 5.3 million babies died in the third trimester of pregnancy and first month following birth. Progress in reducing neonatal mortality and stillbirth rates has lagged behind the substantial progress in reducing postneonatal and ma... more
Ebola disease and Marburg disease outbreaks continue to occur in Africa, with increased frequency. In addition to resulting in high mortality and morbidity, the outbreaks generate fear and mistrust about the response activities within the communitie... more
HIV, viral hepatitis and sexually transmitted infections continue to pose a major public health burden in the WHO European Region, affecting millions of people and causing premature mortality. Despite some progress being made in achieving the target... more