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1
Chagas heart disease (CHD) affects approximately 30% of patients chronically infected with the protozoa Trypanosoma cruzi. CHD is classified into four stages of increasing severity according to electrocardiographic, echocardiographic, and clinical criteria. CHD presents with a myriad of clinical man
...
ifestations, but its main complications are sudden cardiac death, heart failure, and stroke. Importantly, CHD has a higher incidence of sudden cardiac death and stroke than most other cardiopathies, and patients with CHD complicated by heart failure have a higher mortality than patients with heart failure caused by other etiologies. Among patients with CHD, approximately 90% of deaths can be attributed to complications of Chagas disease. Sudden cardiac death is the most common cause of death (55%-60%), followed by heart failure (25%-30%) and stroke (10%-15%). The high morbimortality and the unique characteristics of CHD demand an individualized approach according to the stage of the disease and associated complications the patient presents with. Therefore, the management of CHD is challenging, and in this review, we present the most updated available data to help clinicians and cardiologists in the care of these patients. We describe the clinical manifestations, diagnosis and classification criteria, risk stratification, and approach to the different clinical aspects of CHD using diagnostic tools and pharmacological and non-pharmacological treatments.
more
A century after its discovery, Chagas' disease still represents a major public health challenge in Latin America. Moreover, because of growing population movements, an increasing number of cases of imported Chagas' disease have now been detected in non-endemic areas, such as North America and some E
...
uropean countries. This parasitic zoonosis, caused by Trypanosoma cruzi, is transmitted to humans by infected Triatominae insects, or occasionally by non-vectorial mechanisms, such as blood transfusion, mother to fetus, or oral ingestion of materials contaminated with parasites. Following the acute phase of the infection, untreated individuals enter a chronic phase that is initially asymptomatic or clinically unapparent. Usually, a few decades later, 40-50% of patients develop progressive cardiomyopathy and/or motility disturbances of the oesophagus and colon. In the last decades several interventions targeting primary, secondary and tertiary prevention of Chagas' disease have been attempted. While control of both vectorial and blood transfusion transmission of T cruzi (primary prevention) has been successful in many regions of Latin America, early detection and aetiological treatment of asymptomatic subjects with Chagas' disease (secondary prevention) have been largely underutilised. At the same time, in patients with established chronic disease, several pharmacological and non-pharmacological interventions are currently available and have been increasingly used with the intention of preventing or delaying complications of the disease (tertiary prevention). In this review we discuss in detail each of these issues.
more
Website last accessed on 31.03.2023
Le chikungunya a été identifié pour la première fois en Tanzanie en 1952. Depuis 2004, on constate une propagation rapide du virus du chikungunya, ce dernier ayant été détecté dans plus de 60 pays.
Website last accessed on 31.03.2023
Chikungunya was first identified in Tanzania in 1952. Since 2004, there has been a rapid spread of the chikungunya virus, which has been detected in over 60 countries.
Website last accessed on 31.03.2023
El chikungunya se identificó por primera vez en Tanzania en 1952. Desde 2004, se ha producido una rápida propagación del virus chikungunya, que se ha detectado en más de 60 países.
Website last accessed on 31.03.2023
الشيكونغونيا هو مرض فيروسي ينقله البعوض ويسببه فيروس الشيكونغونيا (CHIKV)، وهو فيروس رنا من جنس فيروس ألفا لعائلة Togaviridae. واسم الشيكونغونيا مشتق
...
ن كلمة في لغة كيماكوندي، تعني "أن بصبح الشئ ملتوياً".
more
La deuxième édition de ce manuel combine et met à jour les éléments contenus dans les trois manuels
antérieurs consacrés à la rotation bilamellaire du tarse, à la méthode de Trabut et à l’évaluation fi nale des
chirurgiens du trichiasis.
Ce manuel est destiné à fournir des informa
...
tions spécifi ques aux formateurs dans le domaine du trichiasis
trachomateux (TT) à d’autres personnes pour qu’elles puissent pratiquer la chirurgie de l’entropion trichiasis.
Il ne traite pas des autres approches et se divise en deux parties. La première présente les spécifi cités de la
formation des futurs chirurgiens du trichiasis et sert de document de référence. Le formateur peut préférer
que les stagiaires lisent directement le document, utilisent ce manuel comme guide dans le cadre d’une
présentation didactique ou l’exploitent d’autres manières comme aide à la formation. Le manuel contient
des connaissances devant être transmises lors de la formation et une description des compétences devant
être acquises et évaluées pendant la pratique et les sessions de chirurgie. La seconde partie est destinée
UNIQUEMENT aux formateurs des futurs chirurgiens et porte sur la sélection et l’évaluation fi nale des
participants.
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Chikungunya virus (CHIKV) is a re-emerging mosquito borne alphavirus responsible
for the recent outbreak in the Americas. Immunologically naïve population in the Americas favors the spread of epidemics. Chikungunya fever is characterized by an abrupt febrile illness, polyarthralgia and maculopapul
...
ar rash. In chikungunya fever, shock or severe hemorrhage is very rarely observed; the onset is more acute and the duration of fever is shorter than dengue disease. The pain is much more pronounced and localized to the joints and tendons in chikungunya fever, in comparison to dengue fever. There is no specific and effective antiviral therapy and vaccines are still in trails. The only effective preventive measures consist of individual protection against mosquito bites and vector control. Disease prevention is important due to the
economic burden it entails. Clinicians need to distinguish chikungunya fever between dengue fever and other diseases to give a successful treatment and prevent disease spreading.
more
En 1998, la Cinquante-et-Unième Assemblée mondiale de la Santé a adopté la résolution
WHA51.11 qui vise l’élimination mondiale du trachome en tant que problème de santé publique
à l’horizon 2020 (1). La stratégie recommandée pour atteindre cet objectif est récapitulée dans
le sig
...
le « CHANCE » qui signifie CHirurgie pour les personnes atteintes de trichiasis
trachomateux (TT – le dernier stade cécitant du trachome) ; Antibiothérapie, Nettoyage du
visage et Changements Environnementaux (2). Les interventions relatives aux volets A, N et CE
sont menées dans des districts entiers dans lesquels les cas de trachome évolutif
(inflammatoire) sont courants, dans le but de traiter les infections oculaires dues à Chlamydia
trachomatis, l’agent pathogène à l’origine du trachome, et de réduire durablement sa
transmission.
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Chagas disease is currently endemic and also predicted to be at increased transmission risk under future climate change scenarios. Similarly, an expansion of areas in the United States at increased risk for Chagas disease transmission is also expected over the next several decades under climate chan
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ge scenarios. Of particular interest is the predicted northern shift of triatomine species to central regions of the United States with historically unsuitable climates for T. cruzi vectors. The weight of evidence regarding the influences climate change may pose on T. cruzi vector species distributions demonstrates the sensitivity of Chagas disease transmission to future climate variability. In order to advance forecasts for the impact climate change may have on Chagas disease transmission in the Americas, it is imperative to
further develop, utilize, and perhaps combine predictive species distribution modeling approaches that integrate accurate, long term data on climate variables, vector species distributions, Chagas disease incidence, as well as other socio-ecological variables.
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La quincuagésima primera Asamblea de la Salud Mundial aprobó la resolución WHA51.11 en
1998, que busca la eliminación mundial del tracoma como problema de salud pública para el 2020
(1). La estrategia recomendada para lograr ese objetivo está encapsulada por las siglas "SAFE", que
represent
...
a: La cirugía para los individuos con triquiasis tracomatosa (TT; la última etapa que causa
ceguera por tracoma); y Antibióticos, Limpieza Facial y Mejoramiento ambiental (2). Las
intervenciones A, F y E se llevan a distritos enteros en los que el tracoma activo (inflamatorio) es
común para tratar la infección ocular causada por Chlamydia trachomatis, el agente causal del
tracoma y reduce de manera sustentable su transmisión.
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The previous report of the WHO Expert Committee on this disease
followed a meeting in 1995. Intensive, coordinated efforts against HAT during
the intervening 18 years have resulted in a decrease in incidence to a point at
which elimination is considered feasible. This report provides informati
...
on about
new diagnostic approaches, new therapeutic regimens and better understanding
of the distribution of the disease with high-quality mapping. The roles of human
and animal reservoirs and the tsetse fly vectors that transmit the parasites are
emphasized. The new information has formed the basis for an integrated strategy
with which it is hoped that elimination of HAT will be achieved. The report also
contains recommendations on the approaches that will lead to elimination of the
disease.
more
Website last accessed on 31.03.2023
Conozca la presentación clínica y la clasificación del dengue.
Website last accessed on 31.03.2023
Youtube Video (Explainity)
Website last accessed on 31.03.23
Dengue is a mosquito-borne viral infection causing a severe flu-like illness and, sometimes causing a potentially lethal complication called severe dengue. The incidence of dengue has increased 30-fold over the last 50 years. Up to 50-100 million infections are
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now estimated to occur annually in over 100 endemic countries, putting almost half of the world’s population at risk.
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Websites last accessed on 31.03.2023
Dengue, Dengue virus, dengue hemorrhagic fever, dengue fever, flavivirus, Aedes mosquitoes, DHF, DF, DSS
This facilitator’s manual is designed to support the implementation of the Dengue Clinical Management training course. The guide contains specific instructions for the facilitator and provides:
- a detailed description of the clinical course of dengue illness, which reflects the dynamic and sys
...
temic nature of dengue that has crucial bearing on the patient’s management;
- a detailed description of the basic pathophysiological changes of severe dengue (i.e. plasma leakage and hypovolaemia/shock) and guidance on the recognition of these changes and appropriate action of management;
- a brief discussion on WHO classification (1997) and its limitations;
- guidance on the differential diagnoses that can be confused with dengue or vice versa; they were described according to the stage of disease;
- a more focused guide on the disease monitoring in accordance with the dynamic changes as the disease progresses;
- emphasis on the importance of monitoring the plasma leakage (haemodynamic status of the patient, clinical signs of plasma leakage and haematocrit);
- a clearer algorithm for fluid management in cases of severe dengue; and
- emphasis on the importance of recognizing or suspecting significant occult bleed. Keep the facilitator’s manual with you each day as you prepare and deliver the information. Use it as a reference when delivering classroom presentations, but avoid reading directly from it during sessions.
more
Website last accessed on 31.03.2023
Learn about dengue clinical presentation and classification.
Website last accessed on 31.03.2023
Learn about dengue diagnosis and testing guidance.
Websites last accessed on 31.03.2023
Learn how to protect your pregnancy from dengue.
