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Manufacturing, safety and quality control of vaccines

World Health Organization WHO (2020) C_WHO
This document is part three in a series of explainers on vaccine development and distribution. Part one focused on how vaccines work to protect our bodies from disease-carrying germs. Part two focused on the ingredients in a vaccine and the three clinical trial phases. This document outlines the... more
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Interim recommendations for use of the Moderna mRNA-1273 vaccine against COVID-19

World Health Organization WHO (2022) C_WHO
nterim guidance, first issued 25 January 2021, updated 15 June 2021, updated 19 November 2021, updated 23 February 2022, updated 18 August 2022
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Interim recommendations for use of the ChAdOx1-S [recombinant] vaccine against COVID-19 (AstraZeneca COVID-19 vaccine AZD1222 Vaxzevria™, SII COVISHIELD™)
recommended

World Health Organization WHO (2022) C_WHO
These WHO interim recommendations on the use of the Astra Zeneca – Oxford University AZD1222 vaccine against Covid-19 were developed on the basis of advice issued by the Strategic Advisory Group of Experts on Immunization (SAGE) and the evidence summary included in the background document referenc... more
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ChAdOx1-S [recombinant], COVID-19 vaccine

World Health Organization WHO (2021) C_WHO
Manufacturers: SK Bioscience Co. Ltd. [COVID-19 Vaccine (ChAdOx1-S [recombinant])] Serum Institute of India Pvt. Ltd. [COVISHIELD™, ChAdOx1 nCoV-19 Corona Virus Vaccine (Recombinant)] Efficacy shown in clinical trials in participants who received the full series of vaccine (2 doses) ir... more
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Interim recommendations for the use of the Janssen Ad26.COV2.S (COVID-19) vaccine

World Health Organization WHO (2022) C_WHO
6 June 2022 These WHO interim recommendations on the use of the Janssen Ad26.COV2.S (COVID-19) vaccine were developed on the basis of advice issued by the Strategic Advisory Group of Experts on Immunization (SAGE) and the evidence summary included in the background document referenced below. Th... more
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Home Care Guidance Update

World Health Organization WHO (2021) C_WHO
22 March 2021
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WHO country cooperation strategy at a glance: Syria

World Health Organization WHO; Eastern Mediterranean Region (2018) CC
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Памятка по применению вакцины против COVID-19: вакцина BNT162b2 Comirnaty® компаний Pfizer/BioNTech (‎международное непатентованное наименование: тозинамеран)‎

World Health Organization WHO (2021) C_WHO
Information about vaccine administration
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Vaccine efficacy, effectiveness and protection

World Health Organization WHO (2021) C_WHO
14 July 2021 This article is part of a series of explainers on vaccine development and distribution. Learn more about vaccines – from how they work and how they’re made to ensuring safety and equitable access – in WHO’s Vaccines Explained series. COVID-19 vaccines have proven to be safe, ... more
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Guidance for surveillance of SARS-CoV-2 variants: Interim guidance, 9 August 2021
recommended

World Health Organization WHO (2021) CC
This document aims to describe a minimum set of surveillance activities recommended at the national level to detect and monitor the relative prevalence of SARS-CoV-2 variants and outline a set of activities for the characterization and assessment of risk posed by these variants. A set of indicators ... more
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Interim statement on COVID-19 vaccine booster doses

World Health Organization WHO (2021) C_WHO
7 August 2021
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Recommandations provisoires concernant l’utilisation du vaccin ChAdOx1-S [‎recombinant]‎ contre la COVID-19 (‎vaccin anti-COVID-19 AZD1222 Vaxzevria™ d’AstraZeneca, COVISHIELD™ de SII)‎
recommended

World Health Organization WHO (2021) C_WHO
orientations provisoires, première publication: 10 février 2021, mise à jour : 21 avril 2021, dernière mise à jour : 30 juillet 2021
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Interim statement on COVID-19 vaccination for children and adolescents

World Health Organization WHO (2022) C_WHO
11 august 2022, updated version
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Interim recommendations for heterologous COVID-19 vaccine schedules

World Health Organization WHO (2021) C_WHO
Overview 16 Dec 2021. This interim guidance pertains to heterologous primary and heterologous boosting schedules of Covid-19 vaccines. It focuses on heterologous schedules combining multiple vaccine platforms (e.g. a vectored vaccine followed by an mRNA vaccine).
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Interim recommendations for use of the Novavax NVX-CoV2373 vaccine against COVID-19: interim guidance, 20 December 2021

World Health Organization WHO (2022) C_WHO
27 September 2022 These WHO interim recommendations for use of the Novavax NVX-CoV2373 vaccine were developed on the basis of advice issued by the Strategic Advisory Group of Experts on Immunization (SAGE) and the evidence summary included in the background document and annexes referenced below.
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COVAXIN® (BBV152) – Inactivated, COVID-19 vaccine

World Health Organization WHO (2022) C_WHO
The COVID-19 Vaccine (Whole Virion Inactivated) BBV152, COVAXIN® vaccine explainer includes key information on the vaccine specific requirements.
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Facility based integrated management of neonatal and childhood illness (F-IMNCI) - Participants manual

Ministry of Health and Family Welfare Government of India; WHO; UNICEF (2009) C_WHO
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Safety and monitoring in patients receiving remdesivir for COVID-19
recommended

World Health Organization WHO (2022) C_WHO
This series of supportive tools are based on the WHO Therapeutics and COVID-19: living guideline. They are intended to provide supportive information for healthcare workers who are prescribing, administering and monitoring patients receiving nirmatrelvir-ritonavir for non-severe COVID-19.
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Good practice statement on the use of second booster doses for COVID 19 vaccines

World Health Organization WHO (2022) C_WHO
18 August 2022
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Good practice statement on the use of variant-containing COVID-19 vaccines

World Health Organization WHO (2022) C_WHO
Declarations of interests were collected from all external contributors and assessed for any conflicts of interest. Summaries of the reported interests can be found on the SAGE meeting website and SAGE Covid-19 Working Group webpage. This guidance should be considered along with the broader COVID-... more