6 July 2021. Three new nucleic acid amplification test (NAAT) classes are endorsed by WHO and included.
The latest operational handbook includes the new classes recommended by WHO. It aims at facilitating the implementation of the WHO recommendations by the Member States, technical partners, and ot...hers involved in managing patients with TB and DR-TB. The operational handbook provides practical information on existing and new tests recommended by WHO, step-by-step advice on implementing and scale-up testing to achieve local and national impact and lastly, model diagnostic algorithms, which are updated to incorporate the latest recommendations. An overview of budgetary considerations and information sheets on each of the newly recommended tests is provided.
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The latest update (28 January 2021) includes the following addition and revision:
biosafety aspects for working with antigen-detecting rapid diagnostic test;
handling new variants of SARS-CoV-2 in the laboratory;
updated assay decontamination before disposal;
personal protectiv...e equipment (PPE) for specimen collection;
addressing chemical hazards and their safe disposal; and
the fourth edition of the WHO Laboratory Biosafety Manual (LBM4) is now available and the terminology in this guidance was aligned with the LBM4.
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The latest update (28 January 2021) includes the following addition and revision:
biosafety aspects for working with antigen-detecting rapid diagnostic test;
handling new variants of SARS-CoV-2 in the laboratory;
updated assay decontamination before disposal;
personal protectiv...e equipment (PPE) for specimen collection;
addressing chemical hazards and their safe disposal; and
the fourth edition of the WHO Laboratory Biosafety Manual (LBM4) is now available and the terminology in this guidance was aligned with the LBM4.
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Orientação provisória 25 de junho de 2021
Recommendations for national testing strategies for SARS-CoV-2 and diagnostic capabilities
The Updated guidelines on Management of tuberculosis in children and adolescents include new recommendations that cover diagnostic approaches for TB, shorter treatment for children with non-severe drug-susceptible TB, a new option for the treatment of TB meningitis, the use of bedaquiline and delama...nid in young children with multidrug- and rifampicin-resistant TB and decentralized and family-centred, integrated models of care for TB case detection and prevention in children and adolescents.
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In 2009, WHO’s Second International Conference on Buruli Ulcer Control and Research resolved to strengthen the capacity of national laboratories to confirm cases of the disease, but advised that “efforts are still needed to develop simple diagnostic tools usable in the field as well as disabilit...y prevention methods”.
In 2013, WHO and the Foundation for Innovative New Diagnostics convened a meeting of Buruli ulcer experts in Geneva, Switzerland (9) at which two priority unmet needs in diagnosis were identified:
a diagnostic test for early detection of Buruli ulcer in symptomatic patients with sufficient positive predictive value to put patients on appropriate treatment; and
a screening test at the primary health care or community level for symptomatic patients with ulcer
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The guidance notes describe key actions that policy-makers at national and subnational levels can take in relation to: diagnostic testing for COVID-19, clinical management of COVID-19, meeting targets for vaccination against COVID-19, maintaining infection control measures for COVID-19 in health-car...e settings, building confidence through risk communication and community involvement, and ensuring that all health-care workers are aware of the risks of COVID-19.
This guidance note focuses on the following areas: COVID-19 diagnostic testing, clinical management of COVID-19, achieving COVID-19 vaccination targets, maintaining COVID-19 infection control measures in health-care settings, building confidence through risk communication and community engagement, and managing COVID-19 infodemia. This guidance note focuses on risk communication and community engagement in the context of COVID-19.
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For the molecular diagnosis of Chagas disease by real-time PCR (polymerase chain reaction), optimization of diagnostic accuracy is desirable. The detection limit of real-time PCR assays for the diagnosis of Trypanosoma cruzi in human serum is affected by various influences including the choice of th...e nucleic acid extraction assay. In this study, three nucleic acid extraction assays were compared regarding their influence on the sensitivity of a T. cruzi-specific real-time PCR with 62 reference sera containing T. cruzi target DNA (deoxyribonucleotide acid). More than 95% of the positive sera were correctly identified after all three nucleic acid extraction strategies with a detection rate ranging from 96.8% (60/62) for the worst assay to 100% (62/62) for the best one. A matched pairs analysis for the comparison of the cycle threshold (Ct) values obtained with the 59 reference samples with positive real-time PCR results after all three nucleic acid extraction schemes indicated differences in a range of about 3 Ct steps. Summarized, all three compared nucleic acid extraction schemes were basically suitable for T. cruzi-specific PCR from serum with some minor differences. However, in the case of low quantities of circulating parasite DNA in the serum of a patient with Chagas disease, even minor effects can make a difference in the individual diagnosis.
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The development of this target product profile (TPP) was led by the WHO Department of Control of Ne-
glected Tropical Diseases (NTD) following standard WHO guidance for TPP development. In order to
identify and prioritize diagnostic needs, a WHO NTD Diagnostics Technical Advisory Group (DTAG)
was... formed, and different subgroups were created to advise on specific NTDs, including a subgroup
working on the human African trypanosomiasis (HAT) diagnostic innovation needs. This group of in-
dependent experts included leading scientists, public health officials and endemic-country end-user rep-
resentatives. Standard WHO Declaration of Interest procedures were followed. A landscape analysis of
the available products and of the development pipeline was conducted, and the salient areas with unmet
needs were identified
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WHO Medical Devices Donations - SPANISH Version - Las tecnologías sanitarias son fundamentales en un sistema de salud operativo. Los dispositivos médicos, en concreto, son cruciales para la prevención, el diagnóstico, el tratamiento y la rehabilitación de enfermedades. Estos documentos están d...irigidos a ingenieros biomédicos, administradores sanitarios,
donantes, organizaciones no gubernamentales e instituciones científicas implicados en la tecnología sanitaria a nivel de distrito, nacional, regional o mundial.
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Este documentopretende fornecer orientações provisórias sobre medições padrão da circunferência da cabeça, padrões de referência para o crescimento, avaliações e investigações clínicas necessárias para estabelecer um diagnóstico de microcefalia e verificar se há anomalias neuroló...gicas associadas
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O recente aumento dos casos de microcefalia e outras patologias neurológicas potencialmente associadas à infecção pelo vírus Zika provocou um aumento da procura de testes laboratoriais para detectar a infecção. Os grupos prioritários para os testes de diagnóstico devem ser
indivíduos sin...tomáticos e mulheres grávidas assintomáticas com possível exposição ao vírus Zika. O presente documento fornece orientações sobre as actuais estratégias de testes da infecção pelo vírus Zika. Este documento será revisto e actualizado à medida que surgirem novas informações.
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Este guia de treinamento explica como identificar os sinais e sintomas das doenças tropicais negligenciadas da pele por meio de suas características visíveis. Contém ainda informações sobre métodos de diagnóstico e manejo de problemas cutâneos comuns que os profissionais de saúde da linha ...de frente podem encontrar.
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6a edición clínica. Nuevo: 4. Vacunas (26 de abril); Nuevo: 5. Pruebas y procedimientos de diagnóstico (7 de abril); Nuevo: 7. COVID-19 persistente (7 de abril)
La presente norma del ministerio de salud de El Salvador establece las disposiciones técnicas que regulan la promoción, prevención, detección, diagnóstico, tratamiento, control y la notifcación obligatoria de los casos de tuberculosis en todas sus formas. Esto incluyen el regulamento de digano...sis y tratamiento de differente grupos de pacientes.
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La presente publicación describe la evidencia científica publicada respecto a la hipertensión como factor pronóstico en pacientes con COVID-19. Se identificó una revisión sistemática que evaluó diferentes desenlaces de pronóstico en pacientes con hipertensión y diagnóstico confirmado de C...OVID-19 con evidencia procedente de treinta estudios.
Esta publicación pertenece al compendio Publicaciones Minsa sobre COVID-19.
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O Ministério da Saúde atualiza o Diagnosticar para Cuidar com o PLANO NACIONAL DE EXPANSÃO DA TESTAGEM PARA COVID-19 (PNE-Teste) que tem a finalidade de expandir o diagnóstico da covid-19 por meio do teste rápido de antígeno (TR-AG), para uso em indivíduos sintomáticos e assintomáticos, par...a monitorar a situação epidemiológica e direcionar os esforços desta Pasta ministerial na contenção da pandemia no território nacional.
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SOBRE ESTE GUIA
Este é um guia de referência rápida que resume as recomendações da Superintendência de Atenção Primária (S/SUBPAV/SAP) para o diagnóstico e o manejo na atenção primária da infecção pelo novo coronavírus. O documento representa o posicionamento da S/SUBPAV/SAP e tem a... função de orientar a assistência clínica nas unidades de atenção primária na cidade do Rio de Janeiro. Em caso de condutas divergentes do que estiver presente neste guia, recomenda-se o devido registro da justificativa em prontuário. Por
ser um campo em constante mudança, este guia será atualizado regularmente, e a versão mais recente estará disponível no site da SUBPAV (www.subpav.org) e no site www.coronavirus.rio, com uma lista das atualizações e suas respectivas datas.
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Instructional Manual for the care of pregnant and postpartum women in the context of the covid-19 pandemic
Este Manual de Recomendações para a Assistência à Gestante e Puérpera visa orientar o acesso e a horizontalidade da assistência durante a pandemia Covid-19, abordando as vias de transmis...são, o diagnóstico precoce e o adequado manejo das gestantes e puérperas nas diversas fases da infecção, definindo diretrizes que evitem a morbimortalidade materna e os agravos ao concepto.
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Accessed on 17.05.2022
Norma técnica Manuales Informes Material de difusión Noticias Normas Técnicas Norma técnicapara el control y la eliminación de la tuberculosis ¡Actualizada! La presente Norma tiene por objetivo establecer las disposiciones que regulan la prevención, detección,diag...nóstico, tratamiento y vigilancia epidemiológica...
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