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The burden of severe asthma in sub-Saharan Africa: Findings from the African Severe Asthma Project

Kirenga, B.J.; Chakaya, J.; Yimer, G. et al. Journal of Allergy and Clinical Immunology: Global (2024) CC

Severe asthma is associated with high morbidity, mortality, and health care utilization, but its burden in Africa is unknown. This article wants to determine the burden (prevalence, mortality, and activity and work impairment) of severe asthma in 3... more

Annual Report: Global Polio Eradication Initiative

World Health Organisation (WHO) (2024) CC

The key to a lasting world free of all forms of poliovirus lies in rapidly interrupting all remaining endemic transmission of WPV in the endemic areas of Pakistan and Afghanistan. This is the only way to ensure that such strains do not re-emerge globally through ... spread. It lays the cornerstone for the eventual cessation of all oral polio vaccine use, in order to eliminate the long-term risks associated with variant poliovirus strains, which is the GPEI’s top operational priority. The target for certifying the world free of all WPV remains end-2026. more

Summary of WHO infection prevention and control guideline for Ebola and Marburg disease: a call for evidence based practice

World Health Organisation (WHO) (2024) C_WHO

This article summarises the process involved in developing the updated guideline and includes an infographic to highlight key IPC recommendations from the guideline, following the patient care pathway from the community to a healthcare facility to d... more

Individual- and Facility-Level Factors Associated with Facility Testing among Men in Malawi: Findings from a Representative Community Survey

Balakasi, K.; Nichols, B. E.; Mphande, M.; et al. (2021) CC2

Men are underrepresented in HIV testing services throughout sub-Saharan Africa. HIV testing is critical to achieve the UNAIDS 95-95-95 goals, as it is the first entry point to HIV care. In Malawi, an estimated 14% of HIV positive men are undiagnosed... more

Guidance on global monitoring for diabetes prevention and control: Framework, indicators and application

World Health Organization WHO (2024) C_WHO

The Guidance on global monitoring for diabetes prevention and control by WHO provides a comprehensive framework to support countries in tracking and managing diabetes prevention, care, and outcomes. This document outlines indicators across 4 domains... more

Mpox Testing Strategy - November 2024

Africa Center for Disease Control and Prevention (2024) CC

Mpox is an emerging zoonotic disease caused by the mpox virus, a member of the Orthopoxvirus genus closely related to the variola virus that causes smallpox. Mpox was first discovered in 1958 when outbreaks of a pox-like disease occurred in monkeys kept for research. The first human case was recorde...d in 1970 in the Democratic Republic of the Congo (DRC) during a period of intensified effort to eliminate smallpox and since then the infection has been reported in a number of African countries. Mpox can spread in humans through close contact, usually skin-to-skin contact, including sexual contact, with an infected person or animal, as well as with materials contaminated with the virus such as clothing, beddings and towels, and respiratory droplets in prolonged face to face contact. People remain infectious from the onset of symptoms until all the lesions have scabbed and healed. The virus may spread from infected animals through handling infected meat or through bites or scratches. Diagnosis is confirmed by polymerase chain reaction (PCR) testing of material from a lesion for the virus’s DNA. Two separate clades of the mpox virus are currently circulating in Africa: Clade I, which includes subclades Ia and Ib, and Clade II, comprising subclades IIa and IIb. Clade Ia and Clade Ib have been associated with ongoing human-to-human transmission and are presently responsible for outbreaks in the Democratic Republic of the Congo (DRC), while Clade Ib is also contributing to outbreaks in Burundi and other countries. In 2022‒2023 mpox caused a global outbreak in over 110 countries, most of which had no previous history of the disease, primarily driven by human-to-human transmission of clade II through sexual contact. In just over a year, over 90,000 cases and 150 deaths were reported to the WHO. For the second time since 2022, mpox has been declared a global health emergency as the virus spreads rapidly across the African continent. On 13 Aug 2024, Africa CDC declared the ongoing mpox outbreak a Public Health Emergency of Continental Security (PHECS), marking the first such declaration by the agency since its inception in 2017.7 This declaration empowered the Africa CDC to lead and coordinate responses to the mpox outbreak across affected African countries. On August 14, 2024, the WHO declared the resurgence of mpox a Public Health Emergency of International Concern (PHEIC) emphasizing the need for coordinated international response. As of August 2024, Mpox has expanded beyond its traditional endemic regions, with new cases reported in countries including Sweden, Thailand, the Philippines, and Pakistan. Sweden has confirmed its first case of Clade 1 variant, which has been rapidly spreading in Africa, particularly in DRC. The emergence of this new variant raises concerns about its potential for higher lethality and transmission rates outside Africa. more

Health equity for persons with disabilities: guide for action: executive summary

World Health Organization WHO (2024) CC

The Disability inclusion guide for action supports ministries of health and their partners in both advancing health equity for persons with disabilities by identifying entry points, and planning appropriate actions that strengthen the health system through disability inclusion. It focuses on address... more

Targeted and selective strategies in measles and rubella vaccination campaigns: Interim guidance

World Health Organization WHO (2025) C_WHO

The World Health Organization provides regional and national strategies and operational plans that aim to support countries in work to achieve measles control and elimination. These are guided by high level frameworks including the Immunization Agenda 2030 and the Measles and Rubella Strategic Frame... more

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Prise en charge clinique, prévention et maîtrise de l'orthopoxvirose simienne (‎variole du singe)‎ : orientations provisoires pour une intervention rapide, 10 juin 2022
recommended

World Health Organization WHO (2022) C_WHO

Interim rapid response guidance, 10 June 2022. It includes considerations for certain populations such as patients with mild disease with considerations for community care, patients with moderate to severe disease, sexually active persons, pregnant... more

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Contaminación atmosférica y salud infantil: prescribir aire limpio: resumen

World Health Organisation (WHO) (2018) C_WHO

This report summarizes the latest scientific knowledge on the links between exposure to air pollution and adverse health effects in children. It is intended to inform and motivate individual and collective action by health care professionals to prev... more

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Cancer in sub-Saharan Africa
recommended

Ngwa, W.; et al. Lancet Oncology Commission (2022) C2

Lancet Oncol 2022; 23: e251–312Published OnlineMay 9, 2022 https://doi.org/10.1016/S1470-2045(21)00720-8 In sub-Saharan Africa (SSA), urgent action is needed to curb a growing crisis in cancer incidence and mortality. Without rapid interventions, data estimates show a major increase in cancer mo... more

Gestion du stress chez les travailleurs humanitaires

Antares Foundation (2012) C1

3ieme edition Les lignes directrices sont organisées autour de huit principes clés correspondant au déroulement du contrat d'un membre du personnel. Le diagramme ci-joint représente visuellement les principes. Chaque principe est accompagné d'indicateurs, de commentaires et d'études de cas de... more

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Integrating Clinical Research into Epidemic Response: The Ebola Experience

Gerald Keusch, Keith McAdam, Patricia Cuff, Michelle Mancher, and Emily R. Busta National Academies of Sciences, Engineering, and Medicine (2017) C1

The 2014–2015 Ebola epidemic in western Africa was the longest and most deadly Ebola epidemic in history, resulting in 28,616 cases and 11,310 deaths in Guinea, Liberia, and Sierra Leone. The Ebola virus has been known since 1976, when two separate outbreaks were identified in the Democratic Repub... more

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MSF Essential Drugs - Practical Guidelines 2022
recommended

Médecins sans Frontières MSF Médecins sans Frontières (2022) C2

Practical guide intended for physicians, pharmacists, nurses and medical auxiliaries. This guide is not a dictionary of pharmacological agents. It is a practical manual intended for health professionals, physicians, pharmacists, nurses and health auxiliaries invoved in curative ... and drug management. We have tried to provide simple, practical solutions to the questions and problems faced by field medical staff, using the accumulated field experience of Médecins Sans Frontières, the recommendations of reference organizations such as the World Health Organization (WHO) and specialized documentation in each field. Also available in French, Spanish and Arabic more

Recommendations for management of common childhood conditions
recommended

World Health Organization (2012)

Evidence for technical update of pocket book recommendations. Newborn conditions, dysentery, pneumonia, oxygen use and delivery, common causes of fever, severe acute malnutrition and supportive care

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Global update on HIV treatment 2013: Results, impact and opportunities

World Health Organization; UNICEF; UNAIDS (2013)

Chapter 1 provides new data on the latest developments in the global treatment effort, highlighting positive trends as well as aspects that require improvement. Chapter 2 summarizes the impact of the scale-up in reducing AIDS-related mortality and new HIV infections. Chapter 3 examines the sequence ... more

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Implementation Manual WHO Surgical Safety checklist

World Alliance for Patient Safety World Health Organization WHO (2008)

The manual provides suggestions for implementing the checklist, understanding that different practice settings will adapt it to their own circumstances. The implementation manual is designed to help ensure that surgical teams are able to implement the checklist consistently. By following a few cri... more

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A global brief on vector-borne diseases

World Health Organization (2014) C_WHO

With this World Health Day, WHO is drawing attention to a group of diseases that are spread by insects and other vectors, the heavy health and economic burdens they impose, and what needs to be done to reduce these burdens. Many of these diseases have been historically confined to distinct geographi... more

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Ebola and Indirect Effects on Health Service Function in Sierra Leone

Håkon Angell Bolkan Donald Alpha Bash-Taqi Mohammed Samai Martin Gerdin Johan von Schreeb (2014)

Bolkan HA, Bash-Taqi DA, Samai M, Gerdin M, von Schreeb J. Ebola and Indirect Effects on Health Service Function in Sierra Leone. PLOS Currents Outbreaks. 2014 Dec 19. Edition 1. doi: 10.1371/currents.outbreaks.0307d588df619f9c9447f8ead5b72b2d. Inpatient health services have been severely affecte... more

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Guide to Local Production: WHO-recommended Handrub Formulations
recommended

World Health Organization WHO (2010) C_WHO

This guide to local production of WHO-recommended handrub formulations is separated into two discrete but interrelated sections: Part A provides a practical guide for use at the pharmacy bench during the actual preparation of the formulation. Users may want to display the material on the wall of ... more

Prise en charge clinique, prévention et maîtrise de l'orthopoxvirose simienne (‎variole du singe)‎ : orientations provisoires pour une intervention rapide, 10 juin 2022 recommended

Cancer in sub-Saharan Africa recommended

MSF Essential Drugs - Practical Guidelines 2022 recommended

Recommendations for management of common childhood conditions recommended

Guide to Local Production: WHO-recommended Handrub Formulations recommended

Prise en charge clinique, prévention et maîtrise de l'orthopoxvirose simienne (‎variole du singe)‎ : orientations provisoires pour une intervention rapide, 10 juin 2022
recommended

Cancer in sub-Saharan Africa
recommended

MSF Essential Drugs - Practical Guidelines 2022
recommended

Recommendations for management of common childhood conditions
recommended

Guide to Local Production: WHO-recommended Handrub Formulations
recommended