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The New England Journal of Medicine has a perspective on Ebola Virus Disease in West Africa — Clinical Manifestations and Management, written by authors who have cared for more than 700 patients with EVD between August 23 and October 4, 2014, in <... largest Ebola treatment unit in Monrovia, Liberia (Free Access) NEJm, November 5, 2014DOI: 10.1056/NEJMp1413084 more
Public health Panoram, Vol.2 Issue 1 March 2016
The objective of the study was the validation and implementation of GeneXpert MTB/RIF for routine use in ... rapid detection of tuberculosis and sensitivity to rifampicin in clinical samples; for this, 1592 respiratory samples were collected and analyzed in the laboratory of Instituto Nacional de Investigación en Salud Pública Guayaquil. The analysis of the results of GeneXpert in comparison with smear microscopy showed an initial sensitivity of 99.8% and specificity of 93.2%; The analysis of discrepancies using the results of the culture as a reference method showed that the GeneXpert results considered false negatives turned out to be true negatives, the same happens with the false positives that correspond to true positives. Recalculated the sensitivity and specificity of the GeneXpert was 99.8% and 100% correspondingly. The comparison with the drugs susceptibility test showed a sensitivity of 91.4% and a specificity of 95.5% for the GeneXpert MTB/RIF system. It is concluded that the implementation of the GeneXpert system allows solution to certain problems associated with the application of conventional diagnostic methodologies, decreasing the waiting times, and increasing the sensitivity and specificity in the diagnosis of drug-resistant tuberculosis, thus generating a valuable opportunity for early diagnosis. more
Background book on Management of the Child with a Serious Infection or Severe Malnutrition
UNICEF trucks water to the camps where people displaced by the conflict have temporarily settled. UNICEF also installed latrines, showers and water storage tanks in ... camps and distributed family hygiene kits to protect children against waterborne diseases. more
Annex 1: Measuring progress towards targets Annex 2: Modelling the impact of the 90-(90)-90 strategy Annex 3: Investment packages by country setting Annex 4: Country strategies Annex 5: Strategi... more
This policy brief identifies and explains the main reasons behind the rise of antimicrobial resistance (AMR) associated with improper use of antibiotics in ... livestock sector. Focusing on the low- and middle- income country setting, this brief provides recommendations for a deliberated policy strategy aimed to prevent healthcare crisis that could happen as a result of AMR. more
This brief considers the rationale for shielding individuals at high risk of severe disease or death from COVID-19 in low- and middleincome countries. It provides an overview of proposed approaches to shielding, discusses ... categories of individuals who may be identified for shielding, and outlines the likely difficulties of these measures and ways to mitigate them. more
There is no secret to our procedure: the daily scanning of the literature helps us to stay afloat in the never-ending waves of new publications abo... more
Guideline for the development of a national plan for the operationalization of vaccination against COVID-19
PLoSONE 14(9):e0223104.https://doi.org/10.1371/journal.pone.0223104. The survey centering on reasons behind community resistance was conducted in Butembo in November during a time of Ebola transmission. A researcher from Catholic University of Grab... more