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Climate change is already having severe impacts across our planet, bringing new and previously unimaginable challenges to the people least responsible for greenhouse gas emissions.
This report, the first we’ve released jointly in the history of our organizations, provides a sobering review of h
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ow just one of those challenges – the increase in deadly heat-waves – threatens to drive new emergency needs in the not-so-distant future.
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Our duty of care
Abdul Rahim, H.F.; M. Fendt-Newlin, S. T. Al-Harahsheh, et al.
Quatar Foundation; Wolrd Innovation Summir ofr Health WISH
(2022)
CC
A global call to action to protect the mental health of health and care workers
The escalation of the war in Ukraine began on 24 February 2022, causing thousands of civilian
casualties; destroying civilian infrastructure, including hospitals, and triggering the fastest-
growing displacement crisis in Europe since World War II. The demographic profile of Ukraine,
combined wit
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h the implementation of martial law and conscription policies, led to an awareness
of gender- and age-related factors within the regional humanitarian response that recognised
the pre-crisis situation of persons of all genders and diversities and how the war and subsequent
regional crisis were compounding the risks that they face.
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This document is a guide defining requirements for quality and safety for malaria rapid diagnostic testing services to safeguard the quality of the results, the safety of the operators and patients and that of the environment for use by national malaria control programmes, regulators, implementers a
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nd rapid diagnostic providers.
more
The marathon to eradicate polio is on its final lap: the world is more than 99% of the way to success. After millennia of living with poliovirus and suffering the paralysis it causes, today nearly all the world’s people live in polio-free countries; two of the three strains of wild poliovirus (WPV
...
) have been eradicated. Some 20 million people are walking who would have been paralysed had it not been for the efforts of national governments and health workers. If eradicating polio has been a marathon, the finishing line is in sight.
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The strengthened plan aims to achieve and sustain a polio-free world through a focus on implementation and accountability. Emphasis will be on cutting outbreak response times; increasing vaccine demand; transforming campaign effectiveness; working systematically through integration; increasing acce
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ss in inaccessible areas; transitioning towards government ownership; and improving decision-making and accountability.
more
2.4 billion reasons to end the global climate and inequality crisis. An estimated 774 million children across the world – or one third of the world’s child population - are living with the dual impacts of poverty and high climate .The country with the highest percentage of children impacted by t
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his double burden is South Sudan (87%), followed by the Central African Republic (85%) and Mozambique (80%).risk,
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Briefing Note 8.
Ecosystem-based adaptation (EbA) is a strategy for adapting to the adverse impacts of climate change by harnessing nature and the services it can provide. This strategy is crucial for cities and peri-urban areas, threatened by a multitude of climate hazards and home to more than ha
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lf the human population as of 2018. Despite some outmigration from the largest cities during the COVID-19 pandemic, urbanization will continue, and by 2035, 62.5 percent of the world’s population is expected to reside in urban areas. However, given the need to retrofit, replace and upgrade deteriorating urban infrastructure, and to meet the challenges of climate change, including the urban heat island effect, droughts and more intense flooding, many experts and policymakers see in these demands an opportunity to reinvent cities as greener, less prone to pandemics, and more liveable.
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Essential health care service disruption due to COVID-19: lessons for sustainability in Nigeria
AHOP National Centre based in Nigeria
World Health Organization WHO, Regional Office Africa
(2022)
C_WHO
The brief concludes that sustaining the continuity of EHS requires policies that ensure a whole-society and systems strengthening approach. This involves increased health care investment, community engagement, disease control regulations, and multisector approaches to improve resilience, EHS quality
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, and equity.
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Cities are uniquely positioned to understand local needs and respond rapidly to changing conditions to safeguard health. These changes require strong city leadership to implement multisectoral, health-relevant policies and public services that engage communities. The response to malaria must be an i
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ntegral part of such policies and processes.
This framework supports the control and elimination of malaria in urban environments. It provides guidance for city leaders, health programmes and urban planners as they respond to the challenges of rapid urbanization in a targeted way. For each urban context, the strategic use of data can inform effective, tailored responses and help build resilience against the threat of malaria and other vector-borne diseases.
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After more than three years without cases, Haiti reported on 2 October 2022 a cluster of cholera cases in the metropolitan area of Port-au-Prince, just as the country was on the verge of being declared cholera- free.
This cholera resurgence in Haiti is happening in a complex operational context,
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amid a volatile socio- political environment marked by blockades, fuel shortages, criminal gang activity and rampant insecurity. Civil unrest and lack of access to the affected communities are deepening the complex humanitarian crisis and hindering emergency response efforts.
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The purpose of this book is to provide an overview of Buruli ulcer (Mycobacterium ulcerans infection) for the medical and scientific communities and the general public alike.
SAMS team rose to meet these challenges, delivering world class COVID treatment with four newly established COVID hospitals complete with 100 ICU beds and state of the art equipment like ventilators, monitors, and oxygen generators. By using innovative technologies, SAMS’ physicians were able to s
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hare the knowledge they gained treating
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Buruli ulcer caused by Mycobacterium ulcerans is a neglected tropical disease characterized by extensive ulceration involving predominantly the upper and lower limbs of patients. The disease is common in rural tropical communities in West and Central Africa, where access to proper health care is lim
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ited. Pathogenesis of the characteristic painless ulcers is linked to the elaboration by M. ulcerans of a lipid toxin called mycolactone that has potent cytopathic, immunosuppressive, and analgesic effects on a host of cells in cutaneous tissues. Mycolactone is known to profoundly inhibit secretion of a plethora of proteins that are essential for wound healing. Even though a combination antibacterial therapy of streptomycin and rifampicin for 8 weeks is effective for treatment, it relies on good and appropriate wound management to prevent secondary bacterial infections and improve healing. Evidence-based interventions for wound care in Buruli ulcer disease are often lacking and have relied on expert advice and recommendations. Surgical interventions are limited to debridement of necrotic tissue and grafting of extensive ulcers, usually after antibiotic therapy. Patients’ rehabilitation is an important component of care to reduce disabilities associated with the disease and proper integration into the community after treatment.
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This report presents key findings from a study carried out on ‘Assessing the effectiveness of targeting mechanisms under PMJAY’. It provides a detailed analysis of potential inclusion and exclusion errors in two select states in India (Haryana and Uttarakhand) to inform National Health Authority
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’s (NHA) policy
and approach around beneficiary targeting.
more
This global progress report attempts to lay the groundwork for the kind of accelerated action needed. Section 1 presents key data, trends and developments in women’s, children’s and adolescents’ health and well-being. That is followed in Section 2 by a deeper dive into the impact of the COVID-
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19 pandemic, which has created and contributed to many threats and challenges to progress for women, children and adolescents. In Section 3, the report concludes with recommendations for accelerating progress towards the achievement of the 2030 Agenda even in such challenging times, with an emphasis on partnership
and clear-eyed recognition of the consequences of failing to do better.
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Nat Commun 9, 5370 (2018). https://doi.org/10.1038/s41467-018-07804-8. Mycobacterium ulcerans is the causative agent of Buruli ulcer, a neglected tropical skin disease that is most commonly found in children from West and Central Africa. Despite the severity of the infection, therapeutic options are
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limited to antibiotics with severe side effects. Here, we show that M. ulcerans is susceptible to the anti-tubercular drug Q203 and related compounds targeting the respiratory cytochrome bc1:aa3. While the cytochrome bc1:aa3 is the primary terminal oxidase in Mycobacterium tuberculosis, the presence of an alternate bd-type terminal oxidase limits the bactericidal and sterilizing potency of Q203 against this bacterium. M. ulcerans strains found in Buruli ulcer patients from Africa and Australia lost all alternate terminal electron acceptors and rely exclusively on the cytochrome bc1:aa3 to respire. As a result, Q203 is bactericidal at low dose against M. ulcerans replicating in vitro and in mice, making the drug a promising candidate for Buruli ulcer treatment.
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Au cours des dix dernières années, de nombreuses catastrophes et crises majeures se sont succédé et ont impacté les vies de millions de gens partout dans le monde. Pour faire face à ces situations critiques, des équipes médicales d’urgence (EMU) nationales et internationales sont réguliè
...
rement détachées pour venir en aide aux populations sinistrées. Les
EMU sont des équipes de professionnels de soins de santé le plus souvent constituées de
médecins, infirmières, psychologues et autres pour apporter des soins cliniques, directement aux personnes touchées par ces catastrophes et ces conflits, et pour apporter leur soutien aux
systèmes de santé locaux. En accord avec le programme de Personnel de santé d’urgence pour la santé mondiale de l’Organisation mondiale de la Santé (OMS), tout professionnel de santé venant d’un pays étranger pour prodiguer des soins sur le lieu d’une catastrophe doit faire partie d’une équipe qualifiée, entraînée, pourvue de moyens matériels et financiers et qui fait preuve d’un minimum requis de niveau de pratique
more
Over the last decade, there have been numerous disasters and major emergencies that have profoundly impacted the lives of millions of people worldwide. To support these crises, national and international emergency medical teams (EMTs) are often deployed to assist disaster affected populations. EMTs
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are teams of healthcare professionals composed most frequently of doctors, nurses, psychologists and others to provide direct clinical care to people affected by disasters and conflicts and to support local health systems. In agreement with the World Health Organization’s (WHO) Global Health Emergency Health Workforce programme, any health professional coming from another country to practice health care in a disaster setting must be part of a team that is qualified, trained, equipped, resourced, and meets minimum acceptable standards to practice.
more
Au cours des dix dernières années, de nombreuses catastrophes et crises majeures se sont succédé et ont impacté les vies de millions de gens partout dans le monde. Pour faire face à ces situations critiques, des équipes médicales d’urgence (EMU) nationales et internationales sont réguliè
...
rement détachées pour venir en aide aux populations sinistrées. Les
EMU sont des équipes de professionnels de soins de santé le plus souvent constituées de
médecins, infirmières, psychologues et autres pour apporter des soins cliniques, directement aux personnes touchées par ces catastrophes et ces conflits, et pour apporter leur soutien aux
systèmes de santé locaux. En accord avec le programme de Personnel de santé d’urgence pour la santé mondiale de l’Organisation mondiale de la Santé (OMS), tout professionnel de santé venant d’un pays étranger pour prodiguer des soins sur le lieu d’une catastrophe doit faire partie d’une équipe qualifiée, entraînée, pourvue de moyens matériels et financiers et qui fait preuve d’un minimum requis de niveau de pratique
more