Buruli ulcer caused by Mycobacterium ulcerans is a neglected tropical disease characterized by extensive ulceration involving predominantly the upper and lower limbs of patients. The disease is common in rural tropical communities in West and Central Africa, where access to proper health care is lim...ited. Pathogenesis of the characteristic painless ulcers is linked to the elaboration by M. ulcerans of a lipid toxin called mycolactone that has potent cytopathic, immunosuppressive, and analgesic effects on a host of cells in cutaneous tissues. Mycolactone is known to profoundly inhibit secretion of a plethora of proteins that are essential for wound healing. Even though a combination antibacterial therapy of streptomycin and rifampicin for 8 weeks is effective for treatment, it relies on good and appropriate wound management to prevent secondary bacterial infections and improve healing. Evidence-based interventions for wound care in Buruli ulcer disease are often lacking and have relied on expert advice and recommendations. Surgical interventions are limited to debridement of necrotic tissue and grafting of extensive ulcers, usually after antibiotic therapy. Patients’ rehabilitation is an important component of care to reduce disabilities associated with the disease and proper integration into the community after treatment.
more
Cardiovascular disease (CVD) is the leading cause of global deaths, with the majority occurring in low- and middle-income countries (LMIC). The primary and secondary prevention of CVD is suboptimal throughout the world, but the evidence-practice gap...s are much more pronounced in LMIC. Barriers at the patient, health-care provider, and health system level prevent the implementation of optimal primary and secondary prevention. Identification of the particular barriers that exist in resource-constrained settings is necessary to inform effective strategies to reduce the identified evidence-practice gaps. Furthermore, targeting modifiable factors that contribute most significantly to the global burden of CVD, including tobacco use, hypertension, and secondary prevention for CVD will lead to the biggest gains in mortality reduction. We review a select number of novel, resource-efficient strategies to reduce premature mortality from CVD, including: (1) effective measures for tobacco control; (2) implementation of simplified screening and management algorithms for those with or at risk of CVD, (3) increasing the availability and affordability of simplified and cost-effective treatment regimens including combination CVD preventive drug therapy, and (4) simplified delivery of health care through task-sharing (non-physician health workers) and optimizing self-management (treatment supporters). Developing and deploying systems of care that address barriers related to the above, will lead to substantial reductions in CVD and related mortality.
more
Handout presentations in PDF for illustrating lectures
Accessed May 2014
Handout presentations in PDF for illustrating lectures
Accessed May 2014
Handout presentations in PDF for illustrating lectures
Accessed May 2014
Handout presentations in PDF for illustrating lectures
Accessed May 2014
This core package of materials provides a comprehensive introduction to the FAST strategy: a focused approach to stopping TB spread in congregate settings. This core package is composed of a booklet, job aids, posters, and a button which serves as a... visual reminder to staff and patients of the importance of this strategy in TB control. FAST can be implemented in both general and TB specific medical settings. Download the complete package from the website https://drtbnetwork.org/fast-tb-infection-control-strategy-core-package
more
Section One
summarizes UNHCR’s mandate of international protecdtion and the aim and principles of emergency
response;
Section Two
deals with emergency management;
Section Three
covers the vi...tal sectors and problem areas in refugee emergencies, including health, food, sanitation
and water, as well as key field activities underpinning the operations such as logistics, community
services and registration. The chapters in this section start with a summary so that readers, who
might not need the full level of detail in each of these chapters, can understand the basic principles of
the subject quickly;
Section Four
gives guidance on the support to field operations, primarily administration and staffing;
The Appendices
include a “Toolbox” which gathers, in one location, the standards, indicators and useful references
used throughout the handbook;
more
This is the first guidance note in a four-part series of notes produced by InterAction to support management,
program and M&E staff in international NGOs to plan, design, manage, conduct and use im...pact evaluations. This first guidance note, Introduction to Impact Evaluation, provides an overview of impact evaluation, explaining how impact evaluation differs from – and complements – other types of evaluation, why impact evaluation should be
done, when and by whom. It describes different methods, approaches and designs that can be used for the different aspects of impact evaluation. The guidance note is also available in French, Arabic and Spanish on https://www.interaction.org/impact-evaluation-notes.
more
This is a detailed manual giving a step by step approach to undertaking the pharmacovigilance of antiretrovirals. It is intended to be a source of practical advice for Pharmacovigilance Centres and health professionals involved in HIV/AIDS preventio...n and treatment programmes. A number of WHO publications are available that provide a background to pharmacovigilance and, as far as possible, that material will not be repeated here. Health officials, planners, the staff of Pharmacovigilance Centres, public health teams and all health workers should become familiar with these publications, which are: • Safety of Medicines: A guide to detecting and reporting adverse drug reactions
more
Guidelines for the Management of Urine Incontinence in Adults
Guidelines for the Management and Therapy of Urinary Tract Infection and Male Genitalia in Indonesia
Guidelines for Therapy and Management of Urinary Tract Infection
Guidelines for Therapy and Management of Acute Coronary Syndrome in Indonesia
Guía de buenas prácticas.Tercera edición
Las directrices se organizan en torno a ocho principios clave que corresponden al curso del contrato de un funcionario. El diagrama adjunto representa los principios de forma visual. Cada principio cuenta con indicadores y comentarios de apoyo, así como ...con estudios de caso diseñados para ayudar al lector a comprender mejor los conceptos en los que se basan los principios y cómo pueden llevarse a la práctica. Los principios e indicadores están pensados para ser aplicados tanto al personal internacional como al nacional y tanto al de oficina como al de campo, reconociendo que puede ser necesario realizar ajustes para tener en cuenta las necesidades y características únicas de cada grupo y de la organización. Constituyen una herramienta de aprendizaje, reflexión y planificación, más que un conjunto de reglas rígidas o soluciones aplicables en todas las condiciones.
more
3ieme edition
Les lignes directrices sont organisées autour de huit principes clés correspondant au déroulement du contrat d'un membre du personnel. Le diagramme ci-joint représente visuellement les principes. Chaque principe est accompagné d'indicateurs, de commentaires et d'études de cas de...stinés à aider le lecteur à mieux comprendre les concepts sur lesquels les principes sont fondés et la manière dont ils peuvent être mis en pratique. Les principes et les indicateurs sont destinés à s'appliquer au personnel international et national ainsi qu'au personnel de bureau et de terrain, en reconnaissant que des ajustements peuvent être nécessaires pour tenir compte des besoins et des caractéristiques uniques de chaque groupe et de l'organisation. Ils constituent un outil d'apprentissage, de réflexion et de planification plutôt qu'un ensemble de règles ou de solutions rigides applicables en toutes circonstances.
more
STATUTORY INSTRUMENTS | SUPPLEMENT No. 8 28th March, 2014 | STATUTORY INSTRUMENTS SUPPLEMENT | to The Uganda Gazette No. 18 Volume CVII dated 28th March, 2014 | Printed by UPPC, Entebbe, by Order of... the Government. | STATUTORY INSTRUMENTS | 2014 No. 29.
more
Sexual violence is a major problem in South Africa, with studies showing that up to one in four women have been raped in their lifetime.
This progress report reflects achievements made during the first year of implementation (through December 2016), as countries have taken actions in line with new or existing national strategies. The most recent data on country progress in 2016 are b...ased on country-reported data and country-developed models using Spectrum software that were reported to UNAIDS in 2017.
more
Neonatal mortality is a major challenge in reducing child mortality rates in Nepal. Despite efforts by the Government of Nepal, data from the last three demographic and health surveys show a rise in the contribution of neonatal deaths to infant and ...child mortality. The Government of Nepal has implemented community-based programs that were piloted and then scaled up based on lessons learned. These programs include, but are not limited to ensuring safe motherhood, birth preparedness package, community-based newborn care package, and integrated management of childhood illnesses. Despite the implementation of such programs on a larger scale, their effective coverage is yet to be achieved. Health system challenges included an inadequate policy environment, funding gaps, inadequate procurement, and insufficient supplies of commodities, while human resource management has been found to be impeding service delivery. Such bottlenecks at policy, institutional and service delivery level need to be addressed incorporating health information in decision-making as well as working in partnership with communities to facilitate the utilization of available services.
more