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Nat Commun 9, 5370 (2018). https://doi.org/10.1038/s41467-018-07804-8. Mycobacterium ulcerans is the causative agent of Buruli ulcer, a neglected tropical skin disease that is most commonly found in children from West and Central Africa. Despite the
...
severity of the infection, therapeutic options are limited to antibiotics with severe side effects. Here, we show that M. ulcerans is susceptible to the anti-tubercular drug Q203 and related compounds targeting the respiratory cytochrome bc1:aa3. While the cytochrome bc1:aa3 is the primary terminal oxidase in Mycobacterium tuberculosis, the presence of an alternate bd-type terminal oxidase limits the bactericidal and sterilizing potency of Q203 against this bacterium. M. ulcerans strains found in Buruli ulcer patients from Africa and Australia lost all alternate terminal electron acceptors and rely exclusively on the cytochrome bc1:aa3 to respire. As a result, Q203 is bactericidal at low dose against M. ulcerans replicating in vitro and in mice, making the drug a promising candidate for Buruli ulcer treatment.
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Myanmar continues to experience a severe - and worsening - humanitarian and human rights crisis. Conflict and violence have escalated across the co
...
untry, impacting children and their families and displacing more than 1.5 million people. Access of conflict-affected populations to services and delivery of humanitarian assistance has been further constrained by restrictions imposed on movement of both people and goods.
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Since fighting between the Sudanese Armed Forces (SAF) and the Rapid Support Forces (RSF) erupted in mid-April, an estimated 6.3 million people have fled their homes, taking refuge inside and outsid
...
e the country, with children representing about half of the people displaced. Sudan is now the country with the largest number of displaced people in the world as prior to the fighting there were 3.7 million people internally displaced in Sudan. It is also now the country with the largest child displacement crisis in the world. ACLED estimates that more than 10,400 people have been killed since the fighting broke out in April, of which about 1,300 killings happened between 30 September and 27 October.
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Antimicrobial resistance(AMR) poses a serious threat to human, animal and environmental health. Implementing ethical practice guidelines on how to use antimicrobials effectively and
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responsibly within the pig industry will contribute in reducing and preventing antimicrobial resistance within the pig industry of South Africa. Members of Pig Vet Society (PVS) SA hereby commit themselvesto put these guidelines into good use in order to preserve the future and effectiveness of antimicrobials. PVS aims to be the leader in prevention of antimicrobial resistance and to encourage the pig industry to work together in achieving this.
more
Confernece Report 15-16 April 2013 - Dublin, Ireland
- Resilient Markets
- Resilient Agriculture
- Resilient People
- Political Leadership for Resilient Growth
Accessed 26 June 2015
A prepared Community is a safe Community
Resource platform
Infection preventions
Hygiene
Training module for Incident response system - Basic & Intermediate
National Institute of Disaster Management (nidm); Ministry of Home Affairs; Government of India
National Institute of Disaster Management (nidm); Ministry of Home Affairs; Government of India
(2020)
C2
Accessed: 16.04.2020
El plan de estudios le ayudará a usted, y a su comunidad, a entender la ciencia del virus que causa el COVID-19 y otros virus similares. Le ayudará a descubrir cómo este virus le afecta o puede afectarle en el futuro. Le ayudará a comprender las medidas que puede tomar para mantenerse a salvo y
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a su comunidad.
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Possible developments in transit countries over the next 6 months, 24 March 2016
Non-conventional humanitarian interventions on Ebola outbreak crisis in West Africa
Tambo, Ernest
(2014)
Infectious Diseases of Poverty 2014, 3:42
http://www.idpjournal.com/content/3/1/42
DOI 10.15252/emmm.201404792 |Published online 30.12.2014
EMBO Molecular Medicine(2014)emmm.201404792
