Q7. SCOPING QUESTION: In adults with moderate-severe depressive disorder, what is the effectiveness and safety of antidepressant medication (ADM) in comparison with psychological treatment?
The WHO mhGAP programme’s existing guidelines recommend that either structured brief psychological treatm...ents (e.g., interpersonal psychotherapy or cognitive behavioural therapy, including behavioural activation) or antidepressant medication (e.g., SSRIsi and tricyclic antidepressants) be considered in adults with moderate-severe depression. Health care workers need to know whether these treatments have different effects, including side-effects, in treating depressive disorder in the short and long term, in order to improve clinical decision-making.
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The present booklet is about gender-responsive substance abuse treatment services for women. It is part of the United Nations Office on Drugs and Crime (UNODC) project to develop tools to support the development and improvement of substance abuse treatment services, based on evidence from the litera...ture and case studies that illustrate practical experiences and lessons learned in providing substance abuse treatment services in various regions of the world.
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Making the Case for Alcohol as a Public Health Threat in the Region. The purpose of this document is to explain the need for making alcohol a top public health priority in the region and the need for national and regional action. Current evidence-based research shows that alcohol consumption and dri...nking patterns in the Americas are at damaging levels, with the region surpassing global averages for many alcohol related problems.
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Q14. SCOPING QUESTION: In adults with psychotic disorders (including schizophrenia), what is the comparative effectiveness and safety of second-generation antipsychotic medications?
The aim of this paper is to investigate how doctors working in primary health care in Latin American address patients with common mental disorders and to investigate how stigma can affect their clinical decisions
PLoSONE 13(11):e0206440.https://doi.org/10.1371/journal.pone.0206440
This 10th edition of the Institute for Health Metrics and Evaluation’s annual Financing Global Health report provides the most up-to-date estimates of development assistance for health, domestic spending on health, health spending on two key infectious diseases – malaria and HIV/AIDS – and fut...ure scenarios of health spending. Several transitions in global health financing inform this report: the influence of economic development on the composition of health spending; the emergence of other sources of development assistance funds and initiatives; and the increased availability of disease-specific funding data for the global health community. For funders and policymakers with sights on achieving 2030 global health goals, these estimates are of critical importance. They can be used for identifying funding gaps, evaluating the allocation of scarce resources, and comparing funding across time and countries.
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The WHO Guidelines on risk reduction of cognitive decline and dementia provide evidence-based recommendations on lifestyle behaviours and interventions to delay or prevent cognitive decline and dementia. These WHO Guidelines are an important tool for health care providers as well as governments, pol...icy-makers and other stakeholders to strengthen their response to the dementia challenge.
Executive Summary available in Arabic, Chinese, French, Russian and Spanish at: https://www.who.int/mental_health/neurology/dementia/guidelines_risk_reduction/en/
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The study on refugee economies shows that refugees and former refugees are contributing positively to Zambia’s economy in various ways and have the potential to contribute even further if legal and other obstacles are removed.
The study targeted mainly Congolese, Burundian, Somali, and Rwandan re...fugees as well as former refugees from Rwanda and Angola in urban areas and the two rural refugee settlements, Mayukwayukwa (Kaoma District/Western Province) and Meheba (Kaulumbila District/North-Western Province).
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Clinical management standard operating procedures.
Ebola virus disease (EVD) is a life-threatening multisystem illness associated with fever and gastrointestinal (GI) symptoms that frequently leads to hypovolaemia, metabolic acidosis, hypoglycaemia, and multi-organ failure. The prolonged 2013–201...6 EVD outbreak in West Africa allowed for an evolution of care such that by outbreak end many patients received individualized and optimized supportive care (oSoC), including volume resuscitation, symptom control, laboratory and bedside monitoring of glucose, electrolyte levels and organ dysfunction, as well as rapid detection and treatment of co-infections, potentially contributing to the downward trend in the case fatality rate (CFR).
This guidance should serve as a foundation for oSoC that should be followed to ensure both the best possible chance for survival and allow for reliable comparison of investigational therapeutic interventions as part of a randomized controlled trial. This guideline provides recommendations for the management of adults and children.
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В данном документе описываются шаги, необходимые для точного измерения интервала QT (QTc) при мониторинге электрокардиографии (ЭКГ) пациентов, получающих краткосроч...ый режим лечения лекарственно-устойчивого туберкулеза (ЛУ-ТБ) или режим, включающий в схему новые препараты. Кроме того, в данном руководстве представлены требования, которые должны быть учтены при приобретении аппарата ЭКГ для мониторинга безопасности лечения пациентов. В силу того, что каждая модель аппарата имеет особые характеристики расчета QTcF (указанные в описании модели), соответственно, это должно быть учтено при выборе и закупе той или иной модели аппарата.
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В цьому документі описуються кроки, необхідні для вимірювання скоригованого інтервалу QT (QTc) при моніторингу електрокардіограми (ЕКГ) у пацієнтів, які або перебува...ть на короткостроковій схемі лікування, або використовують нові препарати для лікування туберкульозу з лікарською стійкістю (ХР ТБ). Крім того, наводяться настанови щодо вимог, які слід враховувати при закупівлі апаратів ЕКГ для моніторингу пацієнтів. До тих пір, поки автоматичний розрахунок інтервалу QT з коригуванням Фредеріція (QTcF) (як зазначено в документі) залежить від функціоналу прибору, вибір щодо закупівлі конкретного апарату залишатиметься на розсуд країн.
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