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Mpox Testing Strategy - November 2024

Africa Center for Disease Control and Prevention (2024) CC

Mpox is an emerging zoonotic disease caused by the mpox virus, a member of the Orthopoxvirus genus closely related to the variola virus that causes smallpox. Mpox was first discovered in 1958 when outbreaks of a pox-like disease occurred in monkeys kept for research. The first human case was recorde...d in 1970 in the Democratic Republic of the Congo (DRC) during a period of intensified effort to eliminate smallpox and since then the infection has been reported in a number of African countries. Mpox can spread in humans through close contact, usually skin-to-skin contact, including sexual contact, with an infected person or animal, as well as with materials contaminated with the virus such as clothing, beddings and towels, and respiratory droplets in prolonged face to face contact. People remain infectious from the onset of symptoms until all the lesions have scabbed and healed. The virus may spread from infected animals through handling infected meat or through bites or scratches. Diagnosis is confirmed by polymerase chain reaction (PCR) testing of material from a lesion for the virus’s DNA. Two separate clades of the mpox virus are currently circulating in Africa: Clade I, which includes subclades Ia and Ib, and Clade II, comprising subclades IIa and IIb. Clade Ia and Clade Ib have been associated with ongoing human-to-human transmission and are presently responsible for outbreaks in the Democratic Republic of the Congo (DRC), while Clade Ib is also contributing to outbreaks in Burundi and other countries. In 2022‒2023 mpox caused a global outbreak in over 110 countries, most of which had no previous history of the disease, primarily driven by human-to-human transmission of clade II through sexual contact. In just over a year, over 90,000 cases and 150 deaths were reported to the WHO. For the second time since 2022, mpox has been declared a global health emergency as the virus spreads rapidly across the African continent. On 13 Aug 2024, Africa CDC declared the ongoing mpox outbreak a Public Health Emergency of Continental Security (PHECS), marking the first such declaration by the agency since its inception in 2017.7 This declaration empowered the Africa CDC to lead and coordinate responses to the mpox outbreak across affected African countries. On August 14, 2024, the WHO declared the resurgence of mpox a Public Health Emergency of International Concern (PHEIC) emphasizing the need for coordinated international response. As of August 2024, Mpox has expanded beyond its traditional endemic regions, with new cases reported in countries including Sweden, Thailand, the Philippines, and Pakistan. Sweden has confirmed its first case of Clade 1 variant, which has been rapidly spreading in Africa, particularly in DRC. The emergence of this new variant raises concerns about its potential for higher lethality and transmission rates outside Africa. more

Mpox Continental Preparedness and Response Plan for Africa
recommended

World Health Organisation (WHO) (2024) C_WHO

On August 13, 2024, the Africa CDC declared the mpox outbreak a Public Health Emergency of Continental Security (PHECS). The following day, the WHO declared it a Public Health Emergency of International Concern (PHEIC). A coordinated, continent-wide response is essential, co-led by the African Union... more

Handbook for national quality policy and strategy

World Health Organization WHO (2018) C_WHO

A practical approach for developing policy and strategy to improve quality of care The handbook outlines an approach for the development of national policies and strategies to improve the quality of care. Such policy and strategy can help clarify the structures, roles and responsibilities within n... more

Building Resilience

Catholic Relief Services (2013)

A guide to facilitating community-managed disaster risk reduction in the Horn of Africa. This manual describes how to help communities implement disaster risk reduction activities. It was written for development workers and community-based organizations in the Horn of Africa, but practitioners can ... more

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Guidance On Evaluating Conflict, Prevention and Peacebuilding Activities: Working draft for application period

DAC Network on Conflict, Peace and Development Co-operation and DAC Network on Development Evaluation OECD Publishing (2008)

This working draft develops guidance on conducting effective evaluations of conflict prevention and peacebuilding work. The current working draft will be used for a one year application phase through 2008. It is the result of an ongoing collaborative project by the OECD DAC Networks on Development E... more

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National nutrition and health survey (NNHS) 2015

US Aid, UK Aid, UNICEF (2015) C1

Report on the nutrition and health situation of Nigeria
Data collection – 13th July to 13th September 2015

Guidelines for drinking-water quality: Fourth edition incorporating the first and second addenda
recommended

World Health Organization (WHO) (2022) C_WHO

Guidance has been updated on a number of chemicals: asbestos, bentazone, chromium, iodine, manganese, microcystins, nickel, silver, tetrachloroethene and trichloroethene. Guidance has also been added for chemicals not previously assessed in the Guidelines: anatoxin-a and analogues, cylindrospermopsi... more

Minimum Economic Recovery Standards

SEEP Network (2010)

In an effort to improve the capabilities and accountability of humanitarian and economic practitioners, the SEEP (Small Enterprise Education and Promotion) Network's Minimum Economic Recovery Standards focus on minimum industry standards for facilitating economic recovery in crisis situations. Th... more

Toolkit on Mapping Legal, Health, and Social Services Responses to Child Maltreatment

World Health Organization; Lucerne University; Children Research Centre (2015)

The toolkit aims to provide researchers with guidance for improving the quality of studies that use administrative data to better ascertain child maltreatment incidence, response and service delivery. However, these are complex studies to conduct, and the toolkit is not meant to be comprehensive. Re... more

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Health worker roles in providing safe abortion care and post-abortion contraception

World Health Organization (2015)

Planned and regulated task shifting and task sharing can have a range of benefits. It can ensure a rational optimization of the available health workforce, address health system shortages of specialized health-care professionals, improve equity in access to health care and increase the acceptability... more

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Impact Evaluation Notes No. 1 - Introduction To Impact Evaluation

Patricia J. Rogers, RMIT University (Australia) and BetterEvaluation InterAction, The Rockefeller Foundation (2012) C3

This is the first guidance note in a four-part series of notes produced by InterAction to support management, program and M&E staff in international NGOs to plan, design, manage, conduct and use impact evaluations. This first guidance note, Introduction to Impact Evaluation, provides an overview of... more

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National Response Efforts to Address Sexual Violence and Exploitation Against Children in Lesotho: A Desktop Study

Weber, Stephanie Arlington, VA: USAID’s AIDS Support and Technical Assistance Resources, AIDSTAR-One, Task Order 1 (2013) C2

Scant data exists on the prevalence of violence against children worldwide. However, available information, including the United Nations Secretary-General’s Study on Violence against Children, shows that violence against children is a global problem. This desktop study aims to glean from published... more

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Water Safety Plans - Training package. Participant workbook

World Health Organization (WHO), International Water Association (IWA) (2012) C_WHO

The workshop is structured around 13 learning modules. The first module (Introduction) gives an overview of WSPs. The last module (Module 12) introduces participants to the quality assurance tool for WSPs (WHO & IWA, 2012). Modules 1–11 relate explicitly to the WSP manual produced by IWA and WHO (... more

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ASEAN Mental Health Systems

ASEAN for Mental Health (2016) C1

The ASEAN Mental Health Systems Report catalogues the situation of mental health in ASEAN Member States. This report provides comprehensive information on the progress made so far by AMS in integrating mental health into national health systems, increasing access to care as well as challenges f... more

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Guidelines to Strengthen the Social Service Workforce for Child Protection

Global Social Service Workforce Alliance, UNICEF (2019)

These guidelines are informed by evidence of ‘what works’ and lessons learned in the field. They are designed to accelerate UNICEF regional and country offices’ programming on social service workforce strengthening, and support work to better plan, develop and support the social services workf... more

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Nurses International Presents: An EKG Interpretation Primer

Nurses International (2021) CC

This book teaches healthcare professionals the basics of EKG interpretation and is available as a creative commons resource. Attribution 4.0 International (CC BY 4.0)

Hand hygiene for all initiative: improving access and behaviour in health care facilities

World Health Organization WHO (2020) C_WHO

The WHO and UNICEF-led Hand Hygiene for All Initiative aims at ensuring implementation for WHO's global recommendations on hand hygiene to prevent and control COVID-19 pandemic, and hand hygiene improvement sustainability in countries as a mainstay of wider infection prevention and control (IPC) and... more

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Drug Regulation in Kenya

LEAP (2021) CC

Drug registration in Kenya started in 1982; the process mainly involves an evaluation committee at the Kenya Pharmacy and Poisons Board (PPB) that aims to approve products based on quality, safety and efficacy.

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Malaria microscopy quality assurance manual – Ver. 2

World Health Organization WHO (2016) C_WHO

This manual is designed primarily to assist managers of national malaria programmes and national reference laboratory responsible for quality assurance of malaria microscopy control. The information is also applicable to non-governmental organizations and funding agencies investing in quality manage... more

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Sanitation Safety Planning

World Health Organization WHO (2022) C_WHO

Manual for step-by-step risk management for safely managed sanitation systems. 2nd edition. This Sanitation safety planning (SSP) manual provides practical, step-by-step guidance to assist in the implementation of the 2018 World Health Organization (WHO) Guidelines on sanitation and health and the ... more

Mpox Continental Preparedness and Response Plan for Africa recommended

Guidelines for drinking-water quality: Fourth edition incorporating the first and second addenda recommended

Mpox Continental Preparedness and Response Plan for Africa
recommended

Guidelines for drinking-water quality: Fourth edition incorporating the first and second addenda
recommended