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National Ethical Guidelines for Biomedical Research Involving Children

Indian Council of Medical Research (ICMR) (2017) C1
These guidelines have been developed specifically to address ethical issues of conducting research in children.
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Consideration of international collaborative projects by Health Ministry’s Screening Committee (HMSC) - further streamlining of the process

Indian Council of Medical Research (ICMR) (2014) C1
F.No. INDO/FRC/442/2008-IHD | INDIAN COUNCIL OF MEDICAL RESEARCH | New Delhi, the 1st July, 2014 | OFFICE MEMORANDUM
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Research Review: Changes in the prevalence and symptom severity of child post-traumatic stress disorder in the year following trauma – a meta-analytic study

Hiller, R.M., Meiser-Stedman, R., Fearon, P., Lobo, S., McKinnon, A., Fraser, A. & Halligan, S.L. (2016) CC
Background: Understanding the natural course of child and adolescent posttraumatic stress disorder (PTSD) has significant implications for the identification of, and intervention for, at-risk youth. We used a meta-analytic approach to examine longitudinal changes in youth PTSD prevalence and symptom... more
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A systematic review of online interventions for mental health in low and middle income countries: A neglected field

Arjadi , R.; Nauta, M. H.; Chowdhary, N.; et al. Global Mental Health (2015) C1
Glob Ment Health (Camb). 2015; 2: e12. Published online 2015 Jul 14. doi: 10.1017/gmh.2015.10 Low and middle income countries (LMICs) are facing an increase of the impact of mental health problems while confronted with limited resources and limited access to mental health care, known as the ‘me... more
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Antipsychotics and mood stabilizers in individuals with bipolar mania

World Health Organization WHO (2015) C_WHO
Q7: In individuals with bipolar mania, are a) antipsychotics, b) mood stabilizers (lithium carbonate, valproate, and carbamazepine) effective and safe
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Antidepressant medicines in individuals with a depressive episode in bipolar disorder

World Health Organization WHO (2012) C_WHO
Q9: Antidepressant medicines in individuals with a depressive episode in bipolar disorder1Q9: In individuals presenting with a depressive episode in bipolar disorder, are antidepressant medicines effective and safe?
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Focused psychosocial interventions for children in low-resource humanitarian settings: a systematic review and individual participant data meta-analysis

Purgato, M., Gross, A.L., Betancourt, T., et al Lancet Glob Health (2018) CC
Results from studies evaluating the effectiveness of focused psychosocial support interventions in children exposed to traumatic events in humanitarian settings in low-income and middle-income countries have been inconsistent, showing varying results by setting and subgroup (eg, age or gender). We a... more
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Preschool PTSD Treatment

Scheeringa, M.S., Amaya-Jackson, L. & Cohen, J. (2010) C2
Version 1.7 Updated October 14, 2010 | Preschool PTSD Treatment (PPT) is a theory-driven, manualized protocol based on cognitive-behavioral therapy (CBT) with modifications for young children. Some of these modifications involve parent-child relationship dynamics that are salient for this age grou... more
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Взаимосвязь факторов питания и микрофлоры кишечника с развитием депрессивных расстройств (обзор)

А. А. Шульдяков, Ю. Б. Барыльник, Е. П. Ляпина et al. Saratov Journal of Medical Scientific Research (2016) C1
Распространенность депрессивных расстройств и их роль в формировании различных вариантов патологии человека обусловливают актуальность поиска новых подходов к ... more
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Role of antidepressants in people with dementia and associated depression

World Health Organization (2012) C_WHO
Q4: For people with dementia with associated depression, do antidepressants when compared to placebo/comparator produce benefits/harm in the specified outcomes?
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Role of Memantine

World Health Organization (2012) C_WHO
Q2: For people with dementia, does memantine, when compared to placebo/comparator, produce benefits/harm in the specified outcomes in non-specialist health settings?
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Packages of Care for Dementia in Low- and Middle-Income Countries

Prince; M.J.; D. Acosta; E. Castro-Costa, et al. PLOS Medicine (2009) CC
November 3, 2009https://doi.org/10.1371/journal.pmed.1000176 PLoS Med 6(11): e1000176. https://doi.org/10.1371/journal.pmed.1000176
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Role of neuroimaging in management of convulsive epilepsy

World Health Organization WHO (2012) C_WHO
Q6: What is the added advantage of doing neuroimaging in people with convulsive epilepsy in non-specialist settings in low and middle income countries?
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EPI 5: Anti-epileptic medicines for medication resistant convulsive epilepsy. [New 2015]

mhGAP; WHO (2015) C_WHO
SCOPING QUESTION: For adults and children with medication-resistant convulsive epilepsy, which anti-epileptic medications produce benefits and/or harm in the specified outcomes when compared to a placebo or a comparator?
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EPI 3: Anti-epileptic medications for management of established status epilepticus [Updated 2015]

mhGAP; WHO (2015) C_WHO
SCOPING QUESTION: In adults with established status epilepticus (i.e., seizures persisting after the first-line treatment with benzodiazepines [or benzodiazepines-resistant status epilepticus]), which anti-epileptic medications are associated with cessation of seizures and reduced adverse effects)? ... more
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Maternal mental health interventions to improve child development

World Health Organization WHO (2012) C_WHO
Q1: What are the effective maternal mental health interventions to prevent developmental problems in early infancy?
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Psychosocial interventions for the management of psychostimulant dependence (2015)

World Health Organization WHO mhGAP; WHO (2015) C_WHO
SCOPING QUESTION:Which psychosocial interventions are effective in the treatment of psychostimulant dependence for adults and young people?
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CH 4: Antidepressants among adolescents with moderate-severe depressive disorder for whom psychosocial interventions have proven ineffective

World Health Organization (2015) C_WHO
(2015) Scoping question: Are antidepressants (specifically, tricyclic antidepressants and selective serotonin reuptake inhibitors) effective and safe in adolescents with moderate-severe depressive disorder for whom psychosocial interventions have proven ineffective?
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Antidepressants (Tricyclic Antidepressants, Selective Serotonin Reuptake Inhibitors) in children 6-12 years of age with depressive episode/disorder

World Health Organization (2012) C_WHO
Q10: Are antidepressants (Tricyclic antidepressants (TCA), Selective serotonin reuptake inhibitors (SSRIs)) effective and safe in children 6-12 years of age with depressive episode/disorder?
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Behaviour change techniques for promoting mental health

World Health Organization (2012) C_WHO
Q13: What is the effectiveness of behaviour change techniques including life skills education in promoting mental health for children and adolescents?