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Mpox Testing Strategy - November 2024

Africa Center for Disease Control and Prevention (2024) CC

Mpox is an emerging zoonotic disease caused by the mpox virus, a member of the Orthopoxvirus genus closely related to the variola virus that causes smallpox. Mpox was first discovered in 1958 when outbreaks of a pox-like disease occurred in monkeys kept for research. The first human case was recorde...d in 1970 in the Democratic Republic of the Congo (DRC) during a period of intensified effort to eliminate smallpox and since then the infection has been reported in a number of African countries. Mpox can spread in humans through close contact, usually skin-to-skin contact, including sexual contact, with an infected person or animal, as well as with materials contaminated with the virus such as clothing, beddings and towels, and respiratory droplets in prolonged face to face contact. People remain infectious from the onset of symptoms until all the lesions have scabbed and healed. The virus may spread from infected animals through handling infected meat or through bites or scratches. Diagnosis is confirmed by polymerase chain reaction (PCR) testing of material from a lesion for the virus’s DNA. Two separate clades of the mpox virus are currently circulating in Africa: Clade I, which includes subclades Ia and Ib, and Clade II, comprising subclades IIa and IIb. Clade Ia and Clade Ib have been associated with ongoing human-to-human transmission and are presently responsible for outbreaks in the Democratic Republic of the Congo (DRC), while Clade Ib is also contributing to outbreaks in Burundi and other countries. In 2022‒2023 mpox caused a global outbreak in over 110 countries, most of which had no previous history of the disease, primarily driven by human-to-human transmission of clade II through sexual contact. In just over a year, over 90,000 cases and 150 deaths were reported to the WHO. For the second time since 2022, mpox has been declared a global health emergency as the virus spreads rapidly across the African continent. On 13 Aug 2024, Africa CDC declared the ongoing mpox outbreak a Public Health Emergency of Continental Security (PHECS), marking the first such declaration by the agency since its inception in 2017.7 This declaration empowered the Africa CDC to lead and coordinate responses to the mpox outbreak across affected African countries. On August 14, 2024, the WHO declared the resurgence of mpox a Public Health Emergency of International Concern (PHEIC) emphasizing the need for coordinated international response. As of August 2024, Mpox has expanded beyond its traditional endemic regions, with new cases reported in countries including Sweden, Thailand, the Philippines, and Pakistan. Sweden has confirmed its first case of Clade 1 variant, which has been rapidly spreading in Africa, particularly in DRC. The emergence of this new variant raises concerns about its potential for higher lethality and transmission rates outside Africa. more

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Diarrhoea Treatment Guidelines
recommended

The MOST Project USAID (2005) C_WHO

Including new recommendations for the use of ORS and zinc Supplementation for Clinic-Based Healthcare Workers

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Guidance on tuberculosis control in vulnerable and hard-to-reach populations

Andreas Sandgren, Marieke J. van der Werf, Netta Beer et al. (2016) CC

This guidance provides an overview of interventions to improve early diagnosis of TB and treatment completion in these populations, as well as factors to consider when developing programmes for health communication, awareness and education, and programme monitoring and evaluation

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Childhood, War, Refugeedom and 'Trauma': Three Core Questions for Mental Health Professionals

Derek Summerfield McGill University - Medical Foundation Series (2000) C1

The rise of the discourse of 'trauma' as a major articulator of suffering within Western culture is a facet of the medicalization of life that has gathered pace in the last century. In recent years, Western mental health professionals have been increasingly involved in services addressing the plight... more

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Methicillin-ResistantStaphylococcus aureus(MRSA):Prevalence and Antimicrobial Sensitivity Pattern among Patients—A Multicenter Study in Asmara, Eritrea

Yohaness Garoy E., Y. Berhane Gebreab, O. Okoth Achila et al. Hindawi (2018) C2

Methicillin-resistant Staphylococcus aureus(MRSA) strainsor multidrug-resistant S.aureus, initially described in 1960s,emerged in the last decade as a cause of nosocomial infections responsible for rapidly progressive, potential fatal diseases including life-threatening pneumonia, necrotizing fascii... more

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Coronavirus SARS-CoV-2/ COVID-19 Pandemic: Information and interim guidelines for pharmacists and the pharmacy workforce

International Pharmaceutical Federation (FIP) (2020) CC

The purpose of this document is to provide relevant information and guidelines on coronavirus outbreaks – and in particular the novel coronavirus SARS-CoV-2 and the diseases it produces, COVID-19 – for pharmacists and the pharmacy workforce, both in a primary care context (i.e. community phar... more

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The Sphere Handbook in Ukrainian
recommended

Sphere (2016) C1

The Ukrainian translation of the Handbook was done by the Rev Marian and Dr Roman Curkowskyj Foundation. Established in 1990 in Toronto, Canada, the Foundation supports the advancement of education, notably through the publication of works in Ukrainian. 2011 Edition.

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Adolescent Mental Health

Chiara Servili, Juliana Yartey, M.T. Yasamy, et. al. World Health Organization WHO, UNICEF (2012) C_WHO

Mapping actions of nongovernmental organizations and other international development organizations

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Politics, Governance, and Reconstruction in Yemen

The Project on Middle East Political Science POMEPS (2018)

Yemen’s war has become one of the world’s worst humanitarian catastrophes . In September 2014, the Ansarallah (Houthi) movement allied with former President Ali Abdullah Saleh to seize control over the capital city Sana’a and renegotiate Yemen’s fragile power-sharing agreement, and then seve... more

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Joint statement on infant and young child feeding in emergencies - Ethiopia, July 2021

FMOH, NDRMC, UNHCR, WHO, Unicef, WFP (2021) C_WHO

The Federal Ministry of Health of Ethiopia (FMOH), the National Disaster Risk Management Commission (NDRMC) and other government actors together with UN agencies (UNICEF, UNHCR, WHO and WFP) and nutrition development partners call for all parties involved in the response to emergencies in Ethiopia t... more

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Increasing tuberculosis burden in Latin America: an alarming trend for global control efforts

O. T. Ranzani; Pescarini, J. M.; Martinez, L.; et. al. BMJ Global Health (2021) CC

The Region of the Americas comprises 46 countries and territories and Brazil and Peru are among the WHO high- TB burden countries. T o illustrate the recent increase in TB incidence in the region, we selected 12 countries from Latin America (Argentina, Brazil, Chile, Colombia, Ecuador, El Salvador... more

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Ebola emergency preparedness in EU Member States: Conclusions from peer-review visits to Belgium, Portugal and Romania

ECDC (European Centre for Disease Prevention and Control) (2015) CC2

This report presents the main characteristics of Ebola emergency preparedness in three EU Member States. Findings are organised in five sections: preparedness planning, organisational structures, recourses and capacities, intersectoral and cross-border collaboration, and country-specific findings

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INEE Minimum Standards Handbooks

Inter-Agency Network for Education in Emergencies (2010) CC

This resource presents "the minimum level of educational quality and access in emergencies through to recovery. The aim of the handbook is to enhance the quality of educational preparedness, response and recovery; to increase access to safe and relevant learning opportunities for all learners, regar... more

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Toolkit 2.0. Expanding and simplifying treatment for pregnant women living with HIV: Managing the transition to Option B/B+

World Health Organization (WHO), Inter-Agency Task Team (IATT), UNICEF (2013) C_WHO

The toolkit is a collection of assessment tools and checklists that describe the key considerations to be taken into account when transitioning to Option B/B+. The toolkit provides a roadmap to support the planning and implementation of Option B/B+, and to help countries scale up more effective inte... more

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Not just in Transit: Drugs, the State and Society in West Africa

WACD West Africa Comission on Drugs WACD (2014) C1

An Independent Report of the West Africa Commission on Drugs

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Food safety andthe Sustainable Development Goals

Delia Grace ILRI (2017) CC

The objective of this briefis to set outlinkages between food safety and the Sustainable Development Goals(SDGs), to identify priority issues,and to suggest how investments in food safety can help attain SDGs.

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Antibiotic Stewardship in the Hospital Environment Getting Started Guide

Best Care Always South Africa (2011) C2

The era of effective antibiotics is coming to a close. In just a few generations, many “miracle medicines”have been beaten into ineffectiveness by the bacteria they were intended to eradicate. Bacteria quickly adapt to the presence of antibacterial agents in order ... more

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Facilitators and Barriers to Accessing Cancer Care in Tanzania: Patients’ Perspectives and Recommendations

Ngilangwa, R. Makene, FS et al. ICCA (2020) CC

The brief highlights some findings as part of a project on Innovation for Cancer Care in Africa (ICCA)1. The study provides insights on the experiences of 62 Tanzanian cancer patients, the journey from their first symptoms to the point of diagnosis and treatment. The project brings together research... more

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The Global Drug Policy Index 2021

Global Commission on Drug Policy (2021) CC

The power of the Global Drug Policy Index lies in its key objective: to score and rank how countries are faring in different areas of drug policy as identified in the UN report ‘What we have learned over the last ten years: A summary of knowledge acquired and produced by the UN system on drug-r... more

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Risk factors for asthma among schoolchildren who participated in a casecontrol study in urban Uganda

Mpairwe, H.; Namutebi, M.; Nkurunungi, G. et al. eLife (2019) CC

Data on asthma aetiology in Africa are scarce. We investigated the risk factors for asthma among schoolchildren (5–17 years) in urban Uganda. We conducted a case-control study, among 555 cases and 1115 controls. Asthma was diagnosed by study clinicians. The main risk factors for asthma were tertia... more

Diarrhoea Treatment Guidelines recommended

The Sphere Handbook in Ukrainian recommended

Diarrhoea Treatment Guidelines
recommended

The Sphere Handbook in Ukrainian
recommended