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Serious adverse events following treatment of visceral leishmaniasis: A systematic review and meta-analysis

Singh-Phulgenda, S., Dahal, P., Ngu, R. et al. PLOS Neglected Tropical Diseases (2021) C1

Despite a historical association with poor tolerability, a comprehensive review on safety of antileishmanial chemotherapies is lacking. We carried out an update of a previous systematic review of all published clinical trials in visceral leishmaniasis (VL) from 1980 to 2019 to document any reported ... more

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Framework towards tuberculosis elimination in low-incidence countries

World Health Organization (2014) C_WHO

This Framework offers a coherent approach for eliminating tuberculosis (TB) in low-incidence countries. It is designed to guide national policy-makers and those responsible for technical aspects of the national TB response in accelerating efforts towards elimination. The document will also be inform... more

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MDR-TB Patient Education Flipchart

United States Agency for International Development (USAID) (2011)

For full publication see: https://drtbnetwork.org/mdr-tb-patient-education-flipchart This tool can be used to educate new patients about TB and MDR-TB. The healthcare provider should review the material together with the patient. A treatment supporter can also use this flipchart at community lev... more

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World Health Organization strategy (‎2022-2026)‎ for the National Action Plan for Health Security

World Health Organisation (WHO) (2023) C_WHO

This strategy defines the World Health Organization (WHO) vision and framework for supporting Member States to accelerate the development, implementation and monitoring of their National Action Plan for Health Security (NAPHS) from 2022 to 2026. The National Action Plan for Health Security (NAPHS) ... more

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Lao People’s Democratic Republic-WHO Country Cooperation Strategy 2024–2028

World Health Organization WHO (2023) C_WHO

This country cooperation strategy (CCS) outlines how the World Health Organization (WHO) will work with the Lao People’s Democratic Republic over the next five years (2024–2028), supporting the implementation of the five-year health sector development plans and the Health Sector Reform Strategy ...2021–2030 to attain the Sustainable Development Goals (SDGs) by 2030. The Lao People’s Democratic Republic experienced substantial economic growth in the 30 years prior to the coronavirus disease (COVID-19) pandemic, contributing to reduced poverty and significant progress toward the SDGs. However, the COVID-19 pandemic brought this development to a halt. It was anticipated that the COVID-19 recovery and the tremendous population growth in recent years would provide opportunities for a shift toward more sustainable and inclusive development in the years ahead. In 2023, however, the contrary was the case. Rural residents, including many ethnic minorities, continued to face marginalization because of limited access to education, health care and economic opportunities. Despite the challenges of COVID-19 and other disease outbreaks, the country has made significant improvements in health. Nonetheless, progress has been uneven and not everyone has benefited from these achievements. In the mountainous region, many people lack access to quality health care because of the unequal distribution of well-trained health-care workers. Preventable deaths due to poor-quality health care for children and newborns, infants and mothers remain a concern, as do communicable diseases such as sexually transmitted infections and tuberculosis. The increasing burden of noncommunicable diseases and the health impact of worsening climate change further heighten the need for strengthened and resilient health systems, which are at risk due to an underfunded health sector and weak economy. This CCS aims to address remaining and future challenges as well as health needs while creating an impact that is sustainable. It identifies three strategic priorities and nine deliverables (Table 1) to support the attainment of the national vision of Health for all by all, as articulated in the 9th Health Sector Development Plan 2021–2025. It contributes to the country’s goals to achieve universal health coverage, graduate from least developed country status by 2026 and attain SDGs by 2030. more

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Therapeutics and COVID-19 (Living Guideline, 10 November 2023)

World Health Organization WHO (2023) C_WHO

WHO has updated its guidelines for COVID-19 therapeutics, with revised recommendations for patients with non-severe COVID-19. This is the 13th update to these guidelines. Updated risk rates for hospital admission in patients with non-severe COVID-19 The guidance includes updated risk rates for... hospital admission in patients with non-severe COVID-19. The current COVID-19 virus variants tend to cause less severe disease while immunity levels are higher due to vaccination, leading to lower risks of severe illness and death for most patients. This update includes new baseline risk estimates for hospital admission in patients with non-severe COVID-19. The new ‘moderate risk’ category now includes people previously considered to be high risk including older people and/or those with chronic conditions, disabilities, and comorbidities of chronic disease. The updated risk estimates will assist healthcare professionals to identify individuals at high, moderate or low risk of hospital admission, and to tailor treatment according to WHO guidelines: **High: **People who are immunosuppressed remain at higher risk if they contract COVID-19, with an estimated hospitalization rate of 6%. **Moderate: **People over 65 years old, those with conditions like obesity, diabetes and/or chronic conditions including chronic obstructive pulmonary disease, kidney or liver disease, cancer, people with disabilities and those with comorbidities of chronic disease are at moderate risk, with an estimated hospitalization rate of 3%. Low: Those who are not in the high or moderate risk categories are at low risk of hospitalization (0.5%). Most people are low risk. Review of COVID-19 treatments for people with non-severe COVID-19 WHO continues to strongly recommend nirmatrelvir-ritonavir (also known by its brand name ‘Paxlovid’) for people at high-risk and moderate risk of hospitalization. The recommendations state that nirmatrelvir-ritonavir is considered the best choice for most eligible patients, given its therapeutic benefits, ease of administration and fewer concerns about potential harms. Nirmatrelvir-ritonavir was first recommended by WHO in April 2022. If nirmatrelvir-ritonavir is not available to patients at high-risk of hospitalization, WHO suggests the use of molnupiravir or remdesivir instead. WHO suggests against the use of molnupiravir and remdesivir for patients at moderate risk, judging the potential harms to outweigh the limited benefits in patients at moderate risk of hospital admission. For people at low risk of hospitalization, WHO does not recommend any antiviral therapy. Symptoms like fever and pain can continue to be managed with analgesics like paracetamol. WHO also recommends against use of a new antiviral (VV116) for patients, except in clinical trials. The update also includes a strong recommendation against the use of ivermectin for patients with non-severe COVID-19. WHO continues to advise that in patients with severe or critical COVID-19, ivermectin should only be used in clinical trials. more

Democratic Republic of Timor-Leste Ministry of Health - Comprehensive TB Guidelines for National Tuberculosis Program, V Edition

Government of Timor-Leste; World Health Organization (2023) CC

The Democratic Republic of Timor-Leste has the highest TB incidence rate in the South East Asian Region - 498 per 100,000, which is the seventh highest in the world. In Timor-Leste TB is the eighth most common cause of death. The salient observations are as follows: In 2018, 487 (12.5%) of the... more

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Zika Virus Infection: Step by Step Guide on Risk Communication and Community Engagement
recommended

Pan American Health Organization (2016) C_WHO

This document offers suggested risk communication actions in relation to Zika virus infection and other health issues linked to this disease. It is directed toward ministers of health and other health sector actors who, with their national (multidis... more

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Leishmaniasis Treatment Market Size, Share, Industry Growth, Trend, Business Opportunities, Challenges, Drivers and Restraint Research Report by 2028

Reports and Data BioSpace (2022) C1

High prevalence of target diseases in rural and developing nations, increased prevalence of malnutrition across the globe, lack of hygiene and poor sanitation facilities, Migratory patterns of population, introduction of new chemical entity in the f... more

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Measuring the availability of human resources for health and its relationship to universal health coverage for 204 countries and territories from 1990 to 2019
recommended

GBD 2019 Human Resources for Health Collaborators The Lancet (2022) CC

A systematic analysis for the Global Burden of Disease Study 2019. The Lancet Vol.399 Issue 10341 p.2129-2154 Human resources for health (HRH) include a range of occupations that aim to promote or improve human health. The UN Sustainable Developme... more

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WHO Guidelines for malaria
recommended

World Health Organization (WHO) (2022) C_WHO

25 Nov 2022 The WHO Guidelines for malaria bring together the Organization’s most up-to-date recommendations for malaria in one user-friendly and easy-to-navigate online platform. The WHO Guidelines for malaria supersedes 2 previous WHO publications: the Guidelines for the treatment of mala... more

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Manual for developing national malaria strategic plans

World Health Organization WHO, Regional Office for Africa (2019) C_WHO

The aim of the framework is to provide guidance to Member States and partners on region-specific priority actions towards the goals, targets and milestones of the GTS. The central pillar of the framework is the adoption of programme phasing and transitioning, aimed at facilitating a tailored approac... more

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Policy brief on tuberculosis-associated disability

World Health Organization WHO (2023) C_WHO

People affected by impairments and disabilities associated with TB are even more likely to belong to marginalized segments of society and are more likely to have their human rights unprotected. The challenges faced by people affected by TB include the consequences of impairment and disability associ... more

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Guidelines for drinking-water quality: Small water supplies

World Health Organization WHO (2024) C_WHO

Small drinking-water supplies commonly experience operational, managerial, technical and resourcing challenges that impact their ability to deliver safe and reliable services. The needs and opportunities associated with these supplies therefore warrant explicit consideration in policies and regulati... more

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mhGAP Intervention Guide Mental Health Gap Action Programme Version 2.0 for mental, neurological and substance use disorders in non-specialized health settings
recommended

Tarun Dua, Nicolas Clark, Neerja Chowdhary et al. World Health Organisation (WHO) (2016) C_WHO

The key updates include: content update in various sections based on new evidence; design changes for enhanced usability; a streamlined and simplified clinical assessment that includes an algorithm for follow-up; inclusion of two new modules - Essential Care and Practice that includes general guid... more

Рациональное использование средств индивидуальной защиты при COVID-19 исоображения применительно к ситуации ихострой нехватки
recommended

World Health Organization WHO (2020) C_WHO

Временное руководство23 декабря 2020 г.

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Guide de déclassement des établissements de soins Ebola
recommended

Organisation Mondiale de la Santé OMS (2015) C_WHO

Pour répondre au besoin urgent de lits requis pour traiter les patients atteints d'Ebola, plusieurs établissements ont été reconfigurés pour prendre en charge, isoler et traiter les patients. Nombre d’entre eux ont été construits au sein d’hôpitaux, d’écoles ou de bâtiments existants... more

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National Guidelines for TB/HIV co-management

National HIVAIDS and Tuberculosis Control Programmes; Ministry of Health and Child Welfare, Zimbabwe (2014) C1

Accessed at March 2014

Management of pneumonia in community settings
recommended

World Health Organization (2004)

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Use of Antiretroviral Drugs for Treating Pregnant Women and Preventing HIV Infection in Infants

World Health Organization (2012) CC

Programmatic update April 2012 Executive Summary

Zika Virus Infection: Step by Step Guide on Risk Communication and Community Engagement recommended

Measuring the availability of human resources for health and its relationship to universal health coverage for 204 countries and territories from 1990 to 2019 recommended

WHO Guidelines for malaria recommended

mhGAP Intervention Guide Mental Health Gap Action Programme Version 2.0 for mental, neurological and substance use disorders in non-specialized health settings recommended

Рациональное использование средств индивидуальной защиты при COVID-19 исоображения применительно к ситуации ихострой нехватки recommended

Guide de déclassement des établissements de soins Ebola recommended

Management of pneumonia in community settings recommended

Zika Virus Infection: Step by Step Guide on Risk Communication and Community Engagement
recommended

Measuring the availability of human resources for health and its relationship to universal health coverage for 204 countries and territories from 1990 to 2019
recommended

WHO Guidelines for malaria
recommended

mhGAP Intervention Guide Mental Health Gap Action Programme Version 2.0 for mental, neurological and substance use disorders in non-specialized health settings
recommended

Рациональное использование средств индивидуальной защиты при COVID-19 исоображения применительно к ситуации ихострой нехватки
recommended

Guide de déclassement des établissements de soins Ebola
recommended

Management of pneumonia in community settings
recommended