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Introduction to Low Cost Sanitation
recommended
Planning, Promotion, Contruction & Design. Manual
This operation update provides a summary of key results achieved against the IFRC Syria Complex Emergency Plan of Action covering 13-month period, from 1 June 2019 to 30 June 2020.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV‑2) causing coronavirus disease 2019 (COVID-19) has reached pandemic levels;
Patients with cardiovascular (CV) risk factors and established cardiovascular disease (CVD) represent a vulnerable population when suffering from COVID-19;
Patien
...
ts with cardiac injury in the context of COVID-19 have an increased risk of morbidity and mortality
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Increasing the Odds: A Series to Understanding Gambling Disorders. Vol.7
All editions of Increasing the Odd sare available as a free download at https://www.icrg.org/resources/monographs
Rev Méd Hondur, Vol 88, Núm 2, 202
African Antibiotic Treatment Guidelines for Common Bacterial Infections and Syndromes – Recommended Antibiotic Treatments in Adult Patients
recommended
Africa Centres for Disease Control and Prevention Center for Disease Dynamics, Economics & Policy
Africa Centres for Disease Control and Prevention Center for Disease Dynamics, Economics & Policy
(2021)
CC
Diretrizes Africanas de Tratamento com Antibióticos para Infeções e Síndromes Bacterianas Comuns
Africa Centres for Disease Control and Prevention Center for Disease Dynamics, Economics & Policy
Africa Centres for Disease Control and Prevention Center for Disease Dynamics, Economics & Policy
(2021)
CC
IAEA Safety Standards for protecting people and the environment
Curr HIV/AIDS Rep. 2022; 19(1): 37–45.
Published online 2022 Jan 29. doi: 10.1007/s11904-021-00589-4.
COVID-19 has had an unprecedented impact on the cascade-of-care among PLWH in LAC. There is a need for
longitudinal studies that assess clinic implication of these pandemic interactions in LAC.
...
more
Ces orientations relatives à la prescription par les infirmières sont destinées à aider les infirmières, les équipes, les associations, les organisations, les enseignants, les organismes de réglementation et les gouvernements du monde entier. Les nations et les régions peuvent évaluer les b
...
esoins de leur population, tout en équilibrant les capacités des infirmières. La planification, la mise en œuvre, le maintien et le suivi de résultats ciblés nécessitent d’adopter une stratégie réfléchie.
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Nat Commun 9, 5370 (2018). https://doi.org/10.1038/s41467-018-07804-8. Mycobacterium ulcerans is the causative agent of Buruli ulcer, a neglected tropical skin disease that is most commonly found in children from West and Central Africa. Despite the severity of the infection, therapeutic options are
...
limited to antibiotics with severe side effects. Here, we show that M. ulcerans is susceptible to the anti-tubercular drug Q203 and related compounds targeting the respiratory cytochrome bc1:aa3. While the cytochrome bc1:aa3 is the primary terminal oxidase in Mycobacterium tuberculosis, the presence of an alternate bd-type terminal oxidase limits the bactericidal and sterilizing potency of Q203 against this bacterium. M. ulcerans strains found in Buruli ulcer patients from Africa and Australia lost all alternate terminal electron acceptors and rely exclusively on the cytochrome bc1:aa3 to respire. As a result, Q203 is bactericidal at low dose against M. ulcerans replicating in vitro and in mice, making the drug a promising candidate for Buruli ulcer treatment.
more
This was a Phase 3, multi-center, randomized, open-label, parallel-group, active control study where 273 male and female patients with first stage Trypanosoma brucei gambiense HAT were treated at six sites: one trypanosomiasis reference center in Angola, one hospital in South Sudan, and four hospita
...
ls in the Democratic Republic of the Congo between August 2005 and September 2009 to support the registration of pafuramidine for treatment of first stage HAT in collaboration with the United States Food and Drug Administration. Patients were treated with either 100 mg of pafuramidine orally twice a day for 10 days or 4 mg/kg pentamidine intramuscularly once daily for 7 days to assess the efficacy and safety of pafuramidine versus pentamidine. Pregnant and lactating women as well as adolescents were included.
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