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Government policy interventions to reduce human antimicrobial use: A systematic review and evidence map

Van Katwyk, S. R.; Grimshaw, J. M.; et al (2019) C2

BACKGROUND: Growing political attention to antimicrobial resistance (AMR) offers a rare opportunity for achieving meaningful action. Many governments have developed national AMR action plans, but most have not yet implemented policy interventions to... reduce antimicrobial overuse. A systematic evidence map can support governments in making evidence-informed decisions about implementing programs to reduce AMR, by identifying, describing, and assessing the full range of evaluated government policy options to reduce antimicrobial use in humans. METHODS AND FINDINGS: Seven databases were searched from inception to January 28, 2019, (MEDLINE, CINAHL, EMBASE, PAIS Index, Cochrane Central Register of Controlled Trials, Web of Science, and PubMed). We identified studies that (1) clearly described a government policy intervention aimed at reducing human antimicrobial use, and (2) applied a quantitative design to measure the impact. We found 69 unique evaluations of government policy interventions carried out across 4 of the 6 WHO regions. These evaluations included randomized controlled trials (n = 4), non-randomized controlled trials (n = 3), controlled before-and-after designs (n = 7), interrupted time series designs (n = 25), uncontrolled before-and-after designs (n = 18), descriptive designs (n = 10), and cohort designs (n = 2). From these we identified 17 unique policy options for governments to reduce the human use of antimicrobials. Many studies evaluated public awareness campaigns (n = 17) and antimicrobial guidelines (n = 13); however, others offered different policy options such as professional regulation, restricted reimbursement, pay for performance, and prescription requirements. Identifying these policies can inform the development of future policies and evaluations in different contexts and health systems. Limitations of our study include the possible omission of unpublished initiatives, and that policies not evaluated with respect to antimicrobial use have not been captured in this review. CONCLUSIONS: To our knowledge this is the first study to provide policy makers with synthesized evidence on specific government policy interventions addressing AMR. In the future, governments should ensure that AMR policy interventions are evaluated using rigorous study designs and that study results are published. more

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WHO policy brief: COVID-19 testing, 14 September 2022

World Health Organization WHO (2022) C_WHO

The World Health Organization (WHO) recognizes the challenges countries face for maintaining their COVID-19 response while addressing competing public health challenges, conflicts, climate change and economic crises. It remains critical for nation... more

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Snapshot report: The state of communication, community engagement and accountability across the Ukraine response (30 September 2022)

CDAC Network Reliefweb OCHA Services (2022) C2

Since the first edition of the CDAC snapshot of communication, community engagement and accountability (CCEA) across the Ukraine response was published in May 2022, a conscious effort has been made by international, national and local responders to ... more

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Rabies epidemiology, prevention and control in Nigeria: Scoping progress towards elimination

Mshelbwala, P.; Weese, J.; Sanni-Adeniyi, O. et al. PLoS Neglected Tropical diseases (2021) CC

Human rabies remains a significant public health problem in Africa with outbreaks reported in most countries. In Nigeria–the most populous country in Africa–rabies causes a significant public health burden partly due to perennial obstacles to implementing a ...al prevention and control program. more

Kangaroo mother care - Implementation strategy for scale-up adaptable to different country contexts

World Health Organisation (WHO) (2023) C_WHO

The KMC implementation strategy targets a broad audience. These include policy-makers and programme managers at national, regional and local levels, government and nongovernmental organizations working in the area of maternal and newborn care, globa... more

Violence against women 60 years and older: Data availability, methodological issues, and recommendations for good practice

UN Women (2024) CC

This briefing note summarizes work undertaken by UN Women and WHO to inform the development of a module on violence against women 60 years and older that can be included in dedicated surveys on violence against women. It provides an overview of the challenges in the availability, measurement, and co... more

Measuring violence against women with disability: Data availability, methodological issues, and recommendations for good practice

UN Women (2024) CC

Developed as part of the UN Women–WHO Global Joint Programme on Violence Against Women Data, this briefing note focuses on the measurement of violence against women with disability and is one in a series of methodological briefing notes for strengthening the measurement and data collection of viol... more

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Technical meeting to support Ebola affected countries on the recovery and resilience plans with a focus on GAVI, the Global Fund and other partners' funding - Report, 9-11 June 2015

World Health Organization (2015)

The objectives of the meeting were to agree on coordinated and aligned support to the 3 countries’ national health recovery plans (Guinea, Liberia, Sierra Leone); to identify cross-cutting areas and opportunities for integration; to identify ways ... more

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Summary the modified Delphi process for common structure and process indicators for hospital antimicrobial stewardship programs

Pollack L. A., D. Plachouras, H. Gruhler et al. Transatlantic Taskforce on Antimicrobial Resistance (TATFAR) (2015) C_CDC

The Transatlantic Task Force on Antimicrobial Resistance (TATFAR) fosters cooperation between the European Union (EU) andthe United States (US) on the issue of antimicrobial resistance. The first TATFAR recommendation refers to appropriate use of an... more

Assessing health systems in Guinea for prevention and control of priority zoonotic diseases: A One Health approach

Standleya C. J., Carlinb E. P., Sorrella E. M. et al. Elsevier (2019) CC

To guide One Health capacity building efforts in the Republic of Guinea in the wake of the 2014–2016 Ebola virus disease (EVD) outbreak, we sought to identify and assess the existing systems and structures for zoonotic disease detection and control. We partnered with the government ministries resp... more

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World Heart Federation Cholesterol Roadmap 2022

Ray, K.K.; Ference, B.A.; Séverin, T. et al. World Heart Federation (2022) CC

Background: Atherosclerotic cardiovascular diseases (ASCVD) including myocardial infarction, stroke and peripheral arterial disease continue to be major causes of premature death, disability and healthcare expenditure globally. Preventing the accumulation of cholesterol-containing atherogenic lipopr... more

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Strengthening countries’ capacities to adopt and adapt evidence-based guidelines: a handbook for guideline contextualization

World Health Organization WHO (2023) C_WHO

Trustworthy, evidence-based health guidelines form the basis of national policies affecting both patients and health-care workers. Emphasizing the link between robust evidence and people’s trust in their health systems, Dr Hans Henri P. Kluge, WHO... more

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Assessment of Medicines Quality Assurance in Rwanda: Overview of Findings and Recommendations for Consideration

Coignez, V., Hajjou, M., and Smine U.S. Agency for International Development (USAID) (2009) C2

PQM conducted an assessment of the medicine quality assurance and quality control systems in Rwanda during November 9-13, 2009. Medicine quality assurance remains to be developed in Rwanda: the country has neither a medicine regulatory authority (MRA) nor a ...al medicine quality control laboratory – the two key institutions to ensure the quality, safety, and efficacy of medicines. The MOH Pharmacy Taskforce (PTF) is to be commended however for successfully controlling the pharmaceutical market to the extent that there is no informal medicines market in Rwanda. Based on its findings, the assessment team expects Rwanda to be able to make great strides in evidence-based medicines quality assurance in the short to medium term, provided it receives adequate technical assistance and financial support. more

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Safety Monitoring of medicinal products

Uppsala Monitoring Centre World Health Organization (2012) C_WHO

Reporting system for the general public - This document aims to provide practical guidelines on how to set up national systems for consumers to report adverse reactions to medicines. The purpose is to help countries set up a well-organized and effec... more

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Zika virus and safety of substances of human origin – A guide for preparedness activities in Europe

European Centre for Disease Prevention and Control (2016) CC

The objective of this document is to guide the preparation and implementation of national preparedness plans for the safety of substances of human origin during outbreaks of Zika virus infection, both in affected and non-affected areas.

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Risk Assessment Roadmap, Myanmar

The Republic of the Union of Myanmar, Ministry of Social Welfare, Relief and Resettlement (MSWRR), Relief and Resettlement Department (RRD) (2015) C1

The need for a roadmap for risk assessment stemmed from the lack of standardised and systematic effort to national risk assessment effort to date. The road map details the process, activities necessary for each step and the availability and accessib... more

Quantification of Health Commodities - A Guide to Forecasting and Supply Planning for Procurement

USAID USAID | DELIVER PROJECT, Task Order 4 (2014) C1

The USAID | DELIVER PROJECT, Task Order 4, developed this guide for quantifying health commodities; it will assist technical advisors, program managers, warehouse managers, procurement officers, and service providers in (1) estimating the total commodity needs and costs for successful implementation... more

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Guidelines for the Prevention and Treatment of Opportunistic Infections Among HIV-Exposed and HIV-Infected Children - AIDSinfo

G. K. Siberry; M. J. Abzug; S. Nachman et al. AIDSinfo (2019) C2

Downloaded from https://aidsinfo.nih.gov/guidelines on 10/19/2019 Recommendations from the National Institutes of Health, Centers for Disease Control and Prevention, the HIV Medicine Association of the Infectious Diseases Society of America and t... more

Handbook for public health capacity-building at ground crossings and cross-border collaboration

World Health Organization WHO (2020) C1

This handbook follows a comprehensive approach to health system strengthening at borders in order to support IHR national focal points and other national agencies in developing and implementing evid... more

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The Core Elements of Human Antibiotic Stewardship Programs in Resource-Limited Settings

Centers for Disease Control and Prevention CDC (2018) C_CDC

Antibiotic stewardship refers to coordinated efforts and activities that seek to measure and improve use of antibiotics. Implementation of ASPs has demonstrated positive public health and clinical impacts including reducing costs, lengths of hospital stays, and the burden of antibiotic resistance wh... more