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People living with HIV

M. Smelyanskaya, J. Duncan; C. Daniels, et al. Stop TB Partnership; The Focus Group Consulting (2017) C1

Key populations brief Accessed November 2017

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TB and the NSP - Are we on track?

Spotlight NSP (2013) C2

NSP Review Engaging with South Africa’s National Strategic Plan for HIV, STIs and TB Edition 7 July – August 2013 A publication of the Treatment Action Campaign and SECTION27 GeneXpert: An imperfect rollout TB in South African prisons: Where to now? Decentralising DR-TB care: How far alon... more

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Isoniazid Prophylactic Therapy for the Prevention of Tuberculosis in HIV Infected Adults: A Systematic Review and Meta- Analysis of Randomized Trials

H. T. Ayele, M. S. M. van Mourik, T. P. A. Debray, et al. PLOS One (2015) CC

PLOS ONE | DOI:10.1371/journal.pone.0142290 November 9, 2015; 1 / 16

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Technology, Research, Education, and Technical Assistance for Tuberculosis (Treat TB)

International Union Against Tuberculosis and Lung Disease; UNION (2014)

treat TB Description of Research Outputs, 2009 - 2014

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Factors associated with HIV testing among young men who have sex with men in Myanmar: a cross‐sectional study

Minh D Pham; Poe Poe Aung; Aye Kyawt Paing et al. (2017) CC

Journal of the International AIDS Society 2017, vol. 20:e25026
In Myanmar, men who have sex with men (MSM) experience high risk of HIV infection. However, access to HIV testing and prevention services remains a challenge among this marginalized population. The objective of this study was to est... more

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Same‐day antiretroviral therapy (ART) initiation in pregnancy is not associated with viral suppression or engagement in care: A cohort study

Langwenya, Nontokozo; Phillips, Tamsin K.; Brittain, Kirsty et al. (2018) CC

Journal of the International AIDS Society Vol. 21 (2018) e25133
Many prevention of mother-to-child HIV transmission programmes across Africa initiate HIV-infected (HIV positive) pregnant women on lifelong antiretroviral therapy (ART) on the first day of antenatal care (“same-day” initiation... more

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HIV and AIDS in South Africa

Avert (2018) C2

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Update of recommendations on first- and second-line antiretroviral regimens

World Health Organization (WHO) World Health Organization (WHO) (2019) C_WHO

July 2019 Policy brief HIV Treatment

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Systematic review and meta-analysis of the adolescent HIV continuum of care in South Africa: the Cresting Wave

B. C. Zanoni; M. Archary; S. Buchan; I. T. Katz; J. E. Haberer BMJ Global Health; Pub Med (2016) C2

Zanoni BC, et al. BMJ Glob Health 2016;1:e000004. doi:10.1136/bmjgh-2015-000004

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Update of recommendations on first- and second-line antiretroviral regimens - Policy Brief

World Health Organization (2019) C_WHO

HIV Treatment

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Mental health challenges among adolescents living with HIV

R. C. Vreeman; B. M. McCoy; S. Lee Journal of the International AIDS Society; PubMed.gov (2017) C2

Vreeman RC et al. Journal of the International AIDS Society 2017, 20(Suppl 3):21497 http://www.jiasociety.org/index.php/jias/article/view/21497 | http://dx.doi.org/10.7448/IAS.20.4.21497

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Undiagnosed tuberculosis in patients with HIV infection who present with severe anaemia at a district hospital

M. Mntonintshi; D. O’Mahony; S.Mabunda; et al. African Journal of Primary Health Care & Family Medicine, AOSIS; NCBI (National Center for Biotechnology Information) (2017) CC

Original Research African Journal of Primary Health Care & Family Medicine ISSN: (Online) 2071-2936, (Print) 2071-2928 Open Access

WHO implementation tool for pre-exposure prophylaxis of HIV infection - Module 12

World Health Organization (WHO) World Health Organization (WHO) (2018) C_WHO

Module 12: Adolescents and young adults July 2018 Module 12: Adolescents and young adults. This module is for people who are interested in providing PrEP services to older adolescents and young adults who are at substantial risk for HIV. It provides information on: factors that influence HIV... more

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Considerations and Principles for Shielding People at High Risk of Severe Outcomes from COVID-19

Social Science in Humanitarian Action (2020) CC

This brief considers the rationale for shielding individuals at high risk of severe disease or death from COVID-19 in low- and middleincome countries. It provides an overview of proposed approaches to shielding, discusses the categories of individuals who may be identified for shielding, and outline... more

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Enhancing response to Omicron SARS-CoV-2 variant

World Health Organization WHO (2022) C_WHO

21 January 2022 The overall threat posed by Omicron largely depends on four key questions: (i) how transmissible the variant is; (ii) how well vaccines and prior infection protect against infection, transmission, clinical disease and death; (iii) how virulent the variant is compared to other varian... more

Improving the Quality of PrEP Implementation for Adolescent Girls and Young Women: An implementation brief to support programming in Eastern and Southern Africa

World Health Organization WHO, Regional Office of Africa; UNICEF (2021) C_WHO

Adolescent girls and young women (AGYW) remain disproportionately affected by HIV in Eastern and Southern Africa (ESA), with 26 per cent of new infections attributed to this population. AGYW face many personal, social and structural barriers to access, uptake and use of traditional HIV prevention me... more

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Recommended package of interventions for HIV, viral hepatis and STI prevention, diagnosis, treatment and care for people who inject drugs: policy brief

World Health Organisation (WHO) (2023) C_WHO

HIV, viral hepatitis and STI epidemics, particularly among people who inject drugs and other key populations, continue to be fuelled by laws and policies criminalizing sex work; drug use or possession; diverse forms of gender expression and sexuality; stigma and discrimination; gender discrimination... more

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Cardiovascular diseases in Africa in the twenty-first century: Gaps and priorities going forward

Minja, N.W.; Nakagaayi, D.; Aliku, T. et al. Frontiers in Cardiovascular Medicine (2022) CC

In 2015, the United Nations set important targets to reduce premature cardiovascular disease (CVD) deaths by 33% by 2030. Africa disproportionately bears the brunt of CVD burden and has one of the highest risks of dying from non-communicable diseases (NCDs) worldwide. There is currently an epide...miological transition on the continent, where NCDs is projected to outpace communicable diseases within the current decade. Unchecked increases in CVD risk factors have contributed to the growing burden of three major CVDs—hypertension, cardiomyopathies, and atherosclerotic diseasesleading to devastating rates of stroke and heart failure. The highest age standardized disability-adjusted life years (DALYs) due to hypertensive heart disease (HHD) were recorded in Africa. The contributory causes of heart failure are changing—whilst HHD and cardiomyopathies still dominate, ischemic heart disease is rapidly becoming a significant contributor, whilst rheumatic heart disease (RHD) has shown a gradual decline. In a continent where health systems are traditionally geared toward addressing communicable diseases, several gaps exist to adequately meet the growing demand imposed by CVDs. Among these, high-quality research to inform interventions, underfunded health systems with high out-of-pocket costs, limited accessibility and affordability of essential medicines, CVD preventive services, and skill shortages. Overall, the African continent progress toward a third reduction in premature mortality come 2030 is lagging behind. More can be done in the arena of effective policy implementation for risk factor reduction and CVD prevention, increasing health financing and focusing on strengthening primary health care services for prevention and treatment of CVDs, whilst ensuring availability and affordability of quality medicines. Further, investing in systematic country data collection and research outputs will improve the accuracy of the burden of disease data and inform policy adoption on interventions. This review summarizes the current CVD burden, important gaps in cardiovascular medicine in Africa, and further highlights priority areas where efforts could be intensified in the next decade with potential to improve the current rate of progress toward achieving a 33% reduction in CVD mortality. more

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Health worker migration from South Africa: causes, consequences and policy responses

Labonté et al Human Resources for Health (2015) CC

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Examining the associations between HIV-related stigma and health outcomes in people living with HIV/AIDS: a series of meta-analyses

S. Rueda; S. Mitra; S. Chen; et al. BMJ Open; Pub Med (2016) CC

Rueda S, et al. BMJ Open 2016;6:e011453. doi:10.1136/bmjopen-2016-011453