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Single-Visit Approach to Cervical Cancer Prevention: Counseling Cue Cards

Pathfinder International (2013)

The single-visit approach to cervical cancer prevention (also referred to as the “See-and-Treat” approach) currently involves visual inspection of the cervix with acetic acid wash and treatment of precancerous lesions with cryotherapy. These cu... more

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Single-Dose Cholera Vaccine in Response to an Outbreak in Zambia

Ferreras, E.; (2018) C2

N Engl J Med 2018; 378:577-579; DOI: 10.1056/NEJMc1711583 A dose of oral vaccine provides effective short-term protection against cholera during an outbreak, a study in Zambia shows. According to researchers, a shortage in the global stockpile of cholera vaccines meant that ...-dose oral vaccination was necessary to tackle an outbreak in Lusaka, Zambia, in February 2016. The emergency vaccination campaign was implemented in April 2016, targeting more than 500,000 people in Lusaka’s overcrowded township areas. The 2016 outbreak happened when Zambia had not reported a case of cholera in four years. To determine the effectiveness of the single-dose cholera vaccine, the researchers enrolled 66 patients with confirmed cholera and 330 people without the disease who were neighbours of the patients. According to the study the effectiveness of the single dose vaccination was about 90 per cent. more

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Effect of a single inactivated poliovirus vaccine dose on intestinal immunity against poliovirus in children previously given oral vaccine: an open-label, randomised controlled trial

Jacob John, et al. The Lancet (2014)

The Lancet, Early Online Publication, 11 July 2014 doi:10.1016/S0140-6736(14)60934-X *Free registration is required to view this article

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Mass Treatment with Single-Dose Azithromycin for Yaws

Oriol Mitjà, M.D., Ph.D., Wendy Houinei, H.E.O., Penias Moses, et al. (2015)

N Engl J Med 2015;372:703-10. Click on the external link to get access to the article

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Mass Treatment with Single-Dose Azithromycin for Yaws. Animation Video

Oriol Mitjà, M.D., Ph.D., Wendy Houinei, H.E.O., Penias Moses, et al. (2015)

Click on the link to open the video

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Fast Breathing as Single Sign of Illness

Global Health Media Project (2016) CC

This video shows how to evaluate and treat the baby with fast breathing as the only sign of illness

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Expanding the Single-Visit Approach for Cervical Cancer Prevention: Successes and Lessons From Burkina Faso

Ouedraogo Y., Furlane G., Fruhauf T. et al. Global Health: Science and Practice (2018) CC

Background: Cervical cancer accounts for 23% of cancer incidence and 22% of cancer mortality among women in Burkina Faso. These proportions are more than 2 and 5 times higher than those of developed countries, respectively. Before 2010, cervical cancer prevention (CECAP) services in Burkina Faso wer...e limited to temporary screening campaigns. Program Description: Between September 2010 and August 2014, program implementers collaborated with the Ministry of Health and professional associations to implement a CECAP program focused on coupling visual inspection with acetic acid (VIA) for screening with same-day cryotherapy treatment for eligible women in 14 facilities. Women with larger lesions or lesions suspect for cancer were referred for loop electrosurgical excision procedure (LEEP). The program trained providers, raised awareness through demand generation activities, and strengthened monitoring capacity. Methods: Data on program activities, service provision, and programmatic lessons were analyzed. Three data collection tools, an individual client form, a client registry, and a monthly summary sheet, were used to track 3 key CECAP service indicators: number of women screened using VIA, proportion of women who screened VIA positive, and proportion of women screening VIA positive who received same-day cryotherapy. Results: Over 4 years, the program screened 13,999 women for cervical cancer using VIA; 8.9% screened positive; and 65.9% received cryotherapy in a single visit. The proportion receiving cryotherapy on the same day started at a high of 82% to 93% when services were provided free of charge, but dropped to 51% when a user fee of $10 was applied to cover the cost of supplies. After reducing the fee to $4 in November 2012, the proportion increased again to 78%. Implementation challenges included difficulties tracking referred patients, stock-outs of key supplies, difficulties with machine maintenance, and prohibitive user fees. Providers were trained to independently monitor services, identify gaps, and take corrective actions. Conclusions: Following dissemination of the results that demonstrated the acceptability and feasibility of the CECAP program, the Burkina Faso Ministry of Health included CECAP services in its minimum service delivery package in 2016. Essential components for such programs include provider training on VIA, cryotherapy, and LEEP; provider and patient demand generation; local equipment maintenance; consistent supply stocks; referral system for LEEP; non-prohibitive fees; and a monitoring data collection system. more

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Yaws: Mass Treatment with Single-Dose Azithromycin for Yaws

Mitjá, O. et al The New England Journal of Medicine (2015) CC

Yaws, an infectious disease caused by Treponema pallidum subspecies pertenue, is endemic in many parts of the world. A community-wide treatment program in Papua New Guinea, in which a single dose of azithromycin was administered, showed substantial ... more

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Efficacy of single versus four repeated doses of praziquantel against Schistosoma mansoni infection in school-aged children from Côte d'Ivoire based on Kato-Katz and POC-CCA: An open-label, randomised

Hoekstra P.T., Casacuberta-Partal M., van Lieshout L. et al (2020) C2

Preventive chemotherapy with praziquantel (PZQ) is the cornerstone of schistosomiasis control. However, a single dose of PZQ (40 mg/kg) does not cure all infections. Repeated doses of PZQ at short intervals might increase efficacy in terms of cure r... more

Protection from a Single Dose of HPV Vaccine A major public health impact from IARC studies of vaccine efficacy

World Health Organisation (WHO) (2023) C_WHO

Protection from a Single Dose of HPV Vaccine A major public health impact from IARC studies of vaccine efficacy.

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A guide for the quality assurance of single use in injection equipment

World Health Organization (2003)

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Guidelines for Post Exposure Chemoprophylaxis with Single dose Rifampicin

National Leprosy Eradication Programme; National Health Mission; Ministry of Health & Social Welfare India (2016) C1

Identifying asthma in population studies: from single entity to a multi-component approach

Marks, G. B. (2005) CC2

Considerable energy has been expended over the last two decades in developing methods for identifying the presence of asthma among participants in population studies. The objective of this endeavour has commonly been to enable epidemiological research on risk factors for asthma, with the ultimate ai... more

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TB and HIV concept note - Investing for impact against tuberculosis and HIV

The Global Fund To fight AIDS, Tuberculosis and Malaria (2015) C2

Single TB and HIV Concept Note Albania 2016-2018 27 April 2015

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Nutrition Policy and Programs in Ghana

A.B. Ghartey The World Bank, et al. (2010) C1

The limitation of a single sector approach. HNP Discussion Paper

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Climate Change and Health. Key facts

World Health Organization (WHO) (2021) C_WHO

Climate change is the single biggest health threat facing humanity, and health professionals worldwide are already responding to the health harms caused by this unfolding crisis. The Intergovernmental Panel on Climate Change (IPCC) has concluded th... more

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Environmental Stewardship and Climate Action Handbook

World Vision (2023) CC

Climate change presents the single biggest threat to human development, and its widespread impacts disproportionately burden the poorest and most vulnerable households in fragile and rural developing contexts – particularly women and children. Ac... more

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What counts as development assistance for reproductive, maternal, newborn, and child health?

Templin T.; Bendavid E. The Lancet (2020) CC

There is no single answer to this question, and therefore no single way to do it. In The Lancet Global Health, Antonia Dingle and colleagues report the convening of a group of policy makers to discu... more

The ‘jigsaw puzzle’ approach to building a diagnostic picture of asthma in primary care over time

Ryan, D.; Kocks, J.; Correia de Sousa, J. et al. International Primary Care Respiratory Group (2023) CC

Since there is no single objective diagnostic test for asthma this study suggests an approach of collecting and assembling pieces of clinical information to create a diagnostic picture, like making a jigsaw puzzle. These pieces should include demons... more

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Yaws and other endemic treponematoses Photos

World Health Organization (2015)

Cases of yaws treated with single-dose oral azithromycin .Click on the link to open the Photo Gallery Accessed Febraury 25, 2015