Q 1: Are antidepressants (Tricyclic Antidepressants (TCA) and Selective Serotonin Reuptake Inhibitors (SSRI)) better (more
effective than/as safe as) than treatment as usual (placebo) in adults with depressive episode/disorder?
Mood disorders
Chapter E.1
2015 edition
(2015)
Scoping question: Are antidepressants (specifically, tricyclic antidepressants and selective serotonin reuptake inhibitors) effective and safe in adolescents with moderate-severe depressive disorder for whom psychosocial interventions have proven ineffective?
Anxiety disorders
Chapter F.2
The toolkit presents step-by-step guidance that district health teams (DHTs), district leaders, MOH/UNEPI, immunisation partners, and civil society organisations (CSOs) can use to engage NHS and maximise the benefits of their participation in strengthening RI through activities such as community dia...logue meetings. Tables and annexes outline this process
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Q7. SCOPING QUESTION: In adults with moderate-severe depressive disorder, what is the effectiveness and safety of antidepressant medication (ADM) in comparison with psychological treatment?
The WHO mhGAP programme’s existing guidelines recommend that either structured brief psychological treatm...ents (e.g., interpersonal psychotherapy or cognitive behavioural therapy, including behavioural activation) or antidepressant medication (e.g., SSRIsi and tricyclic antidepressants) be considered in adults with moderate-severe depression. Health care workers need to know whether these treatments have different effects, including side-effects, in treating depressive disorder in the short and long term, in order to improve clinical decision-making.
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Q10: Are antidepressants (Tricyclic antidepressants (TCA), Selective serotonin reuptake inhibitors (SSRIs)) effective and safe in children 6-12 years of age with depressive episode/disorder?
Accessed January 22, 2019.
This updated version include important research that has added to our knowledge about effective treatments for
child and adolescent depression. Its goal is to help parents and families make informed decisions about getting the best care for a child with depression. For ...easy use, it is presented in Frequently Asked Questions (FAQ) format.
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Anxiety disorders
Chapter F.3
Posttraumatic stress disorder (PTSD) in children and adolescents occurs as a result of a child’s exposure to one or more traumatic events: actual or threatened death, serious injury, or sexual violence. The victim may experience the event, witness it, learn about it from close family members or fr...iends, or experience repeated or extreme exposure to aversive details of the event. Potentially traumatic events include physical or sexual assaults, natural disasters, and accidents.
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This Practice Parameter reviews the evidence from research and clinical experience and highlights significant advances in the assessment and treatment of posttraumatic stress disorder since the previous Parameter was published in 1998. It highlights the importance of early identification of posttrau...matic stress disorder, the importance of gathering information from parents and children, and the assessment and treatment of comorbid disorders. It presents evidence to support trauma-focused psychotherapy, medications, and a combination of interventions in a multimodal approach.
Journal of the American Academy of Children & Adolescents Psychiatry, Vol. 49 No. 4 APRIL 2010 pp.414-430
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Q 2: How long should treatment with antidepressants continue in adults with depressive episode/disorder?
Sci Rep. 2016; 6: 25920. Published online 2016 May 16. doi: 10.1038/srep25920
NICE guideline | This guideline covers recognising, assessing and treating post-traumatic stress disorder (PTSD) in children, young people and adults. It aims to improve quality of life by reducing symptoms of PTSD such as anxiety, sleep problems and difficulties with concentration. Recommendations ...also aim to raise awareness of the condition and improve coordination of care.
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WHO guidelines on the pharmacological treatment of persisting pain in children with medical illnesses
Suchtmedizinische Reihe
Band 5
Accessed: 14.03.2019
with recommended essential medicines for common diseases in patients in Stockholm County Council (Healthcare Region), Sweden
Anxiety disorders
Chapter F.1
2018 edition
This guide covers: Treatment That Works; Myths About Treatment; Success Stories; Resources | Do you or a loved one have PTSD? There is no need to suffer. Treatment works. If you have PTSD—posttraumatic stress disorder — you don’t have to suffer. There are good treatments that can help. This b...ooklet describes therapies and medications that are proven to help people with PTSD.
You’ll hear from experts about what treatment is like, and how it can help you. Don’t let PTSD get in the way of your enjoyment of life, hurt your relationships, or cause problems for you at
work or school. PTSD treatment works.
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Objectives and scope of the document
This document was developed to provide recommended management strategies for problems and disorders that are specifically related to the occurrence of a major stressful event. The recommended strategies will form the basis of a new module to be added to the WHO ...(2010) mhGAP Intervention Guide for use in non-specialized specialized health-care settings.
The scope of the problems covered by these guidelines is:
symptoms of acute stress in the first month after a potentially traumatic event, with the following subtypes:
- symptoms of acute traumatic stress (intrusion, avoidance and hyperarousal) in the first month after a potentially traumatic event;
- symptoms of dissociative (conversion) disorders in the first month after a potentially traumatic event;
- non-organic (secondary) enuresis in the first month after a potentially traumatic event (in children);
- hyperventilation in the first month after a potentially traumatic event;
- insomnia in the first month after a potentially traumatic event;
posttraumatic stress disorder (PTSD);
bereavement in the absence of a mental disorder.
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