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Q 1: Are antidepressants (Tricyclic Antidepressants (TCA) and Selective Serotonin Reuptake Inhibitors (SSRI)) better (more effective than/as safe as) than treatment as usual (placebo) in adults with depressive episode/disorder?
Mood disorders Chapter E.1 2015 edition
(2015) Scoping question: Are antidepressants (specifically, tricyclic antidepressants and selective serotonin reuptake inhibitors) effective and safe in adolescents with moderate-severe depressive disorder for whom psychosocial interventions have proven ineffective?
Anxiety disorders Chapter F.2
The toolkit presents step-by-step guidance that district health teams (DHTs), district leaders, MOH/UNEPI, immunisation partners, and civil society organisations (CSOs) can use to engage NHS and maximise the benefits of their participation in strengthening RI through activities such as community dia... more
Q7. SCOPING QUESTION: In adults with moderate-severe depressive disorder, what is the effectiveness and safety of antidepressant medication (ADM) in comparison with psychological treatment? The WHO mhGAP programme’s existing guidelines recommend that either structured brief psychological treatm... more
Q10: Are antidepressants (Tricyclic antidepressants (TCA), Selective serotonin reuptake inhibitors (SSRIs)) effective and safe in children 6-12 years of age with depressive episode/disorder?
Accessed January 22, 2019. This updated version include important research that has added to our knowledge about effective treatments for child and adolescent depression. Its goal is to help parents and families make informed decisions about getting the best care for a child with depression. For ... more
Anxiety disorders Chapter F.3
Posttraumatic stress disorder (PTSD) in children and adolescents occurs as a result of a child’s exposure to one or more traumatic events: actual or threatened death, serious injury, or sexual violence. The victim may experience the event, witness it, learn about it from close family members or fr... more
This Practice Parameter reviews the evidence from research and clinical experience and highlights significant advances in the assessment and treatment of posttraumatic stress disorder since the previous Parameter was published in 1998. It highlights the importance of early identification of posttrau... more
Q 2: How long should treatment with antidepressants continue in adults with depressive episode/disorder?
Sci Rep. 2016; 6: 25920. Published online 2016 May 16. doi: 10.1038/srep25920
NICE guideline | This guideline covers recognising, assessing and treating post-traumatic stress disorder (PTSD) in children, young people and adults. It aims to improve quality of life by reducing symptoms of PTSD such as anxiety, sleep problems and difficulties with concentration. Recommendations ... more
WHO guidelines on the pharmacological treatment of persisting pain in children with medical illnesses

Medikamentenabhängigkeit

Prof. Dr. rer. nat. Gerd Glaeske Dr. med. Rüdiger Holzbach Deutsche Hauptstelle für Suchtfragen e.V.; Bundeszentrale für gesundheitliche Aufklärung (2019) C2
Suchtmedizinische Reihe Band 5 Accessed: 14.03.2019
with recommended essential medicines for common diseases in patients in Stockholm County Council (Healthcare Region), Sweden
Anxiety disorders Chapter F.1 2018 edition

Understanding PTSD Treatment (Guide)

National Center for PTSD U.S. Department of Veterans Affairs (2011) C2
This guide covers: Treatment That Works; Myths About Treatment; Success Stories; Resources | Do you or a loved one have PTSD? There is no need to suffer. Treatment works. If you have PTSD—posttraumatic stress disorder — you don’t have to suffer. There are good treatments that can help. This b... more
Objectives and scope of the document This document was developed to provide recommended management strategies for problems and disorders that are specifically related to the occurrence of a major stressful event. The recommended strategies will form the basis of a new module to be added to the WHO ... more