Treatment of second-stage gambiense human African trypanosomiasis relied on toxicarsenic-based derivatives for over 50 years. The availability and subsequent use of eflornithine,initially in monotherapy and more recently in combination with nifurtimox (NECT), has drasticallyimproved the pro...gnosis of treated patients. However, NECT logistic and nursing requirementsremain obstacles to its deployment and use in peripheral health structures in rural sub-SaharanAfrica. Two oral compounds, fexinidazole and SCYX-7158, are currently in clinical development.The main scope of this article is to discuss the potential impact of new oral therapies to improvediagnosis-treatment algorithms and patients’access to treatment, and to contribute to reach theobjectives of the recently launched gambiense humanAfrican trypanosomiasis elimination program
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Schistosomiasis is a helminthic infection and one of the neglected tropical diseases (NTDs). It is caused by blood flukes of the genus Schistosoma. It is an important public health problem, particularly in poverty-stricken areas, especially those within the tropics and subtropics. It is estimated th...at at least 236 million people worldwide are infected, 90% of them in sub-Saharan Africa, and that this disease causes approximately 300,000 deaths annually. The clinical manifestations are varied and affect practically all organs. There are substantial differences in the clinical presentation, depending on the phase and clinical form of schistosomiasis in which it occurs. Schistosomiasis can remain undiagnosed for a long period of time, with secondary clinical lesion. Here, we review the clinical profile of schistosomiasis. This information may aid in the development of more efficacious treatments and improved disease prognosis.
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Version 15.4.2020
Mögliche Szenarien mit unterschiedlicher Daür und Wirkungsstärke wesentlicher Gegenmaßnahmen
Posttraumatic stress disorder (PTSD) in children and adolescents occurs as a result of a child’s exposure to one or more traumatic events: actual or threatened death, serious injury, or sexual violence. The victim may experience the event, witness it, learn about it from close family members or fr...iends, or experience repeated or extreme exposure to aversive details of the event. Potentially traumatic events include physical or sexual assaults, natural disasters, and accidents.
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The Global Campaign Against Epilepsy “Out of the Shadows”
Global Campaign Against Epilepsy
Chagas disease is a tropical parasitic infection transmitted by crawling, blood-sucking insects (kissing bugs). You may have flu-like symptoms or none at all. But the disease can lead to life-threatening complications. With prompt treatment, most people with Chagas disease, also known as American tr...ypanosomiasis, recover fully.
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ifo Schnelldienst, 2020, 73, Nr. 12, 46-57
Der Artikel zeigt, dass diskriminierende Strukturen und die besondere Schutzbedürftigkeit von geflüchteten Kindern durch das Auftreten von Covid-19 verstärkt werden. Geflüchtete Kinder verfügen über weniger digitale Ausstattung, teilweise werden si...e nicht von der Schulpflicht erfasst, sowohl ehrenamtliche als auch psychosoziale Angebote werden erschwert und die Integration durch „Social Distancing“ beeinträchtigt
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Clinical Guidelines for the Diagnose and Management of Nosocomial Pneumonia in Indonesia
Guidelines for the Diagnose and Management of Community Pneumonia in Indonesia
Each year more than one million women are diagnosed with breast cancer worldwide over half of whom will die from the disease. Breast cancer is the most common cancer and the leading cause of cancer death for women
Die Bundespsychotherapeutenkammer (BPtK) möchte mit diesem Standpunkt über die psychischen Belastungen und Erkrankungen bei Flüchtlingen informieren, auf die Problemfelder und Handlungsbedarfe bei der Gesundheitsversorgung psychisch erkrankter Flüchtlinge aufmerksam machen und Möglich...keiten aufzeigen, wie die Versorgung von Flüchtlingen, die unter einer psychischen Erkrankung leiden, in Deutschland verbessert werden kann.
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Bachelorarbeit - Departement: Gesundheit; Institut: Institut für Hebammen; Studienjahr: 2008; Eingereicht am: 20.05.2011; | Zielsetzung: Das Ziel dieser Arbeit ist, Risikofaktoren, welche eine posttraumatische Belastungsstörung infolge eines traumatischen Geburtserlebnisses begünstigen, zu analys...ieren.
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Suchtmedizinische Reihe
Band 5
Accessed: 14.03.2019
This is an abridged version of the 2019 Standards containing the evidence-based recommendations most pertinent to primary care. The tables and figures have been renum-bered from the original document to match this version. The complete 2019 Standards of Care do...cument, including all supporting references, is available at professional.diabetes.org/standards.
This is an abridged version of the American Diabetes Association’s Standards of Medical Care in Diabetes—2019. Diabetes Care2018;42(Suppl. 1):S1–S194. The complete 2019 Standards supplement, including all supporting references, is available at professional.diabetes.org/standards.
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This Tuberculosis guide has been developed jointly by Médecins Sans Frontières and Partners In Health. It aims at providing useful information to the clinicians and health staff for the comprehensive management of tuberculosis. Forms of susceptible and resistant tuberculosis, tuberculosis in child...ren, and HIV co-infection are all fully addressed.
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