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En el análisis demográfico se calcularon tasas específicas por sexo y edad para el período respecto al cual se dispone de datos oficiales (1950-2013), de donde se derivó la estimación del índice de sobremortalidad
masculina, la importancia relativa de las defunciones causadas por accidentes... de tráfico con respecto al total de fallecimientos, las variaciones de cambio porcentual en el tiempo, los coeficientes de correlación de Pearson y las estimaciones a futuro (2017) de la tasa de mortalidad por accidentes de tráfico terrestre, así como una descripción y análisis detallado de gráficos que ilustran las variaciones temporales. more
El maltrato infantil ha pasado a considerarse en la última década un problema de salud pública. Numerosos trabajos que analizan los efectos directos en la salud mental infantil informan de una alta prevalencia en alteraciones internalizantes, externalizantes y en trastorno por estrés postraumát...ico (TEPT). La Terapia Cognitivo Conductual-Focalizada en el Trauma ha sido la única que ha recibido la mención de tratamiento eficaz bien establecido en población infanto-juvenil. La técnica de exposición prolongada se considera de elección para el tratamiento del TEPT, si bien numerosos pacientes presentan dificultades para llevarla a cabo. La realidad virtual se ha convertido en una alternativa que facilita la técnica de exposición..more
Эти публикации представляют собой серию справочных пособий, специально адресованных различным группам специалистов и социальных работников, имеющих отношение к ...работе по предотвращению самоубийств. Они подготовлены в рамках программы SUPRE (Предотвращение самоубийств), глобальной инициативы ВОЗ по предотвращению самоубийствmore
Esta publicación está dirigida a profesionales en formación o con práctica en salud mental y no para el público general. Las opiniones vertidas en este libro son de responsabilidad de sus autores y no representan necesariamente el punto de vista del Editor o de IAC...APAP. Esta publicación busca describir los mejores tratamientos y las prácticas basadas en la evidencia científica disponible en el tiempo en que se escribió, tal como fueron evaluadas por los autores, y éstas pueden cambiar como resultado de una nueva investigación. Los lectores deberán aplicar este conocimiento a los pacientes de acuerdo con las directrices y leyes de cada país en el que ejercen profesionalmente. Algunos medicamentos puede que no estén disponibles en algunos países por lo que los lectores deberán consultar la información específica del fármaco debido a que ni se mencionan todas las dosis ni todos los efectos no deseados. Las citas de organizaciones, publicaciones y enlaces de sitios de Internet tienen la finalidad de ilustrar situaciones o se enlazan como una fuente adicional de información; lo que no significa que los autores, el editor o IACAPAP
avalen su contenido o recomendaciones, que deberán ser analizadas de manera crítica por el lector. Los sitios de Internet, a su vez, también pueden cambiar o dejar de existir.more
Z. Z. Aunga; Y. M. Saw; T. N. Saw; et al.International Journal of Infectious Diseases; Elsevier; International Society for infectious diseases
(2019)
C2
International Journal of Infectious Diseases 80 (2019) 10–15
journal homepage: www.elsevier.com/locate/ijid
l’IMC et le gain de poids gestationnel sont des facteurs déterminants des risques de
résultats de grossesse, de la santé de la mère et de l’enfant. Cette étude analyse l’incidence de la
nutrition chez les femmes enceintes sur la santé néonatale au Bénin. Les résultats d’estimation... par les
équations simultanées montrent que le gain de poids gestationnel insuffisant ou excessif a des effets
néfastes aussi bien sur la santé de la mère que sur celui de l’enfant. L’étude montre que la majorité des
femmes béninoises étudiées, avec un IMC faible ou normal n’atteignent pas le gain de poids
gestationnel recommandé en fin de grossesse. La plupart des nouveau-nés de petits poids de naissance
sont nés de femme dont l’IMC est normal, ce qui renforce la théorie bien connue que l’IMC n’est pas un
bon indicateur de la malnutrition chez la femme enceinte.more
Journal of the International AIDS Society Vol. 21 (2018) e25133
Many prevention of mother-to-child HIV transmission programmes across Africa initiate HIV-infected (HIV positive) pregnant women on lifelong antiretroviral therapy (ART) on the first day of antenatal care (“same-day” initiation...). However, there are concerns that same-day initiation may limit patient preparation before starting ART and contribute to subsequent non-adherence, disengagement from care and raised viral load. We examined if same-day initiation was associated with viral suppression and engagement in care during pregnancy.
The data suggest that same-day ART initiation during pregnancy is not associated with lower levels of engagement in care or viral suppression through 12 months post-delivery in this setting, providing reassurance to ART programmes implementing Option B+.
https://doi.org/10.1002/jia2.25133more
Cryptococcal disease is one of the most common opportunistic infections among people living with advanced HIV disease and is a major contributor to severe illness, morbidity, and mortality, particularly in sub-Saharan Africa.
These guidelines update the recommendations that were first released i...n 2018 on diagnosing, preventing, and managing cryptococcal disease. In response to important new evidence that became available in 2021, these new guidelines strongly recommend a single high dose of liposomal amphotericin B as part of the preferred induction regimen for the treatment of cryptococcal meningitis in people living with HIV. This simplified regimen - a single high dose of liposomal amphotericin B paired with other standard medicines (flucytosine and fluconazole) - is as effective as the previous WHO standard of care, with the benefits of lower toxicity and fewer monitoring demands.
The objective of these guidelines is to provide updated, evidence-informed recommendations for treating adults, adolescents and children living with HIV who have cryptococcal disease. These guidelines are aimed at HIV programme managers, policymakers, national treatment advisory boards, implementing partners and health-care professionals providing care for people living with HIV in resource-limited settings with a high burden of cryptococcal disease.more
Stewardship is defined as “the careful and responsible management of something entrusted to one’s care”. It was originally applied in the health-care setting as a tool for optimizing antimicrobial use, termed “antimicrobial stewardship” (AMS). Stewardship has since be...en applied in the context of governance of the health sector as a whole, taking responsibility for the health and well-being of the population and guiding health systems at the national and global level.more
The World Health Organization (WHO) has recommended a universal antiretroviral therapy (ART) for all HIVinfected children before the age of two since 2010, but this implies an early identification of these infants. We described the Prevention of Mother-to-Child HIV Transmission (PMTCT) cascade, the ...staffing and the quality of infrastructures in pediatric HIV care facilities, in Ouagadougou, Burkina Faso.more
Histoplasmosis is a disease caused by the fungus Histoplasma capsulatum. This disease is highly endemic in some regions of North America, Central America, and South America and is also reported in certain countries of Asia and Africa. It often affects people with impaired immunity, including people ...living with HIV, among whom the most frequent clinical presentation is disseminated histoplasmosis. The symptoms of disseminated histoplasmosis are non-specific and may be indistinguishable from those of other infectious diseases, especially disseminated tuberculosis (TB), thus complicating diagnosis and treatment. Histoplasmosis is one of the most frequent opportunistic infections caused by fungal pathogens among people living with HIV in the Americas and may be responsible for 5–15% of AIDS-related deaths every year in this Region. These guidelines aim to provide recommendations for the diagnosis, treatment, and management of disseminated histoplasmosis in persons living with HIVmore
PlosOne December 10, 2014 https://doi.org/10.1371/journal.pone.0111913
Plastic pollution is ubiquitous throughout the marine environment, yet estimates of the global abundance and weight of floating plastics have lacked data, particularly from the Southern Hemisphere and remote regions. Here we re...port an estimate of the total number of plastic particles and their weight floating in the world's oceans from 24 expeditions (2007–2013) across all five sub-tropical gyres, costal Australia, Bay of Bengal and the Mediterranean Sea conducting surface net tows (N = 680) and visual survey transects of large plastic debris (N = 891). Using an oceanographic model of floating debris dispersal calibrated by our data, and correcting for wind-driven vertical mixing, we estimate a minimum of 5.25 trillion particles weighing 268,940 tons. When comparing between four size classes, two microplastic <4.75 mm and meso- and macroplastic >4.75 mm, a tremendous loss of microplastics is observed from the sea surface compared to expected rates of fragmentation, suggesting there are mechanisms at play that remove <4.75 mm plastic particles from the ocean surface.more