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Worldwide trends in the burden of asthma symptoms in school-aged children: Global Asthma Network Phase I cross-sectional study

Asher, I.; Rutter, C.E.; Bissell, K. et al. The Lancet (2021) CC

Asthma is the most common chronic disease in children globally. The Global Asthma Network (GAN) Phase I study aimed to determine if the worldwide burden of asthma symptoms is changing. This updated cross-sectional study used the same methods as the International study of Asthma and Allergies in Chi...ldhood (ISAAC) Phase III. Asthma symptoms were assessed from centres that completed GAN Phase I and ISAAC Phase I (1993–95), ISAAC Phase III (2001–03), or both. We included individuals from two age groups (children aged 6–7 years and adolescents aged 13–14 years) who self-completed written questionnaires at school. We estimated the 10-year rate of change in prevalence of current wheeze, severe asthma symptoms, ever having asthma, exercise wheeze, and night cough (defined by core questions in the questionnaire) for each centre, and we estimated trends across world regions and income levels using mixed-effects linear regression models with region and country income level as confounders. Overall, 119 795 participants from 27 centres in 14 countries were included: 74 361 adolescents (response rate 90%) and 45 434 children (response rate 79%). About one in ten individuals of both age groups had wheeze in the preceding year, of whom almost half had severe symptoms. Most centres showed a change in prevalence of 2 SE or more between ISAAC Phase III to GAN Phase I. Over the 27-year period (1993–2020), adolescents showed a significant decrease in percentage point prevalence per decade in severe asthma symptoms (–0·37, 95% CI –0·69 to –0·04) and an increase in ever having asthma (1·25, 0·67 to 1·83) and night cough (4·25, 3·06 to 5·44), which was also found in children (3·21, 1·80 to 4·62). The prevalence of current wheeze decreased in low-income countries (–1·37, –2·47 to –0·27], in children and –1·67, –2·70 to –0·64, in adolescents) and increased in lower-middle-income countries (1·99, 0·33 to 3·66, in children and 1·69, 0·13 to 3·25, in adolescents), but it was stable in upper-middle-income and high-income countries. Trends in prevalence and severity of asthma symptoms over the past three decades varied by age group, country income, region, and centre. The high worldwide burden of severe asthma symptoms would be mitigated by enabling access to effective therapies for asthma. more

Task-shifting to improve asthma education for Malawian children: a qualitative analysis

Nkhalamba, L.; Rylance, S.; Muula, S. A. et al. Human Resources for Health (2021) CC

Background Asthma education, a key component of long-term asthma management, is challenging in resource-limited settings with shortages of clinical staff. Task-shifting educational roles to lay (non-clinical) staff is a potential solution. We conducted a randomised controlled trial of an enhanced a... more

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Summary of childhood asthma guidelines, 2021: A consensus document

Manjra, A.I.; van Niekerk, A.; White, D.A. et al. South African Medical Journal (2021) CC

Asthma is the most common chronic illness of childhood. The prevalence is rising and the mortality and morbidity from asthma are unacceptably high in South Africa. This article emphasizes the importance to make a correct diagnosis based, most importantly, on the clinical history and supported by inv... more

Wie stärke ich die psychische Gesundheit meines Kindes?

Zürcher Hochschule für Angewandte Wissenschaften (2021) C2

Dieser Flyer richtet sich an Eltern von 6- bis 12-jährigen Kindern. Er soll Sie als Eltern für das Thema psychische Gesundheit sensibilisieren und Ihnen alltagsnahe Tipps geben, wie Sie die psychische Gesundheit Ihres Kindes stärken können. Die Empfehlungen haben wir auf der Grundlage von wisse... more

Как укрепить психическое здоровье детей?

Zürcher Hochschule für Angewandte Wissenschaften (2021) C2

Данный флаер предназначен для родителей детей в возрасте от 6 до 12 лет. Он призван привлечь внимание родителей к теме психического здоровья и содержит повседневные... more

Як покращити психічне здоров’я моєї дитини?

Zürcher Hochschule für Angewandte Wissenschaften (2021) C2

Ova brošura je namijenjena roditeljima djece od 6 do 12 godina. Svrha ove brošure je da vas kao roditelje senzibilizira za temu mentalnog zdravlja i da vam pruži savjete iz svakodnevnice, kako da ojačate mentalno zdravlje vašeg djeteta. Preporuke smo izradili na osnovu naučne literature i uz ... more

Kako da ojačam mentalno zdravlje svog djeteta?

Zürcher Hochschule für Angewandte Wissenschaften (2021) C2

Delivering Results for Children in Malawi

Unicef (2021) C_UNICEF

Malawi is a small and beautiful country in south-central Africa. It is divided into three administrative regions: south, central and north. The regions are further subdivided into 28 districts. The Southern Region is the most densely populated, while the Northern Region is the least populated.

Renewable energy solutions improve children’s health and wellbeing in Malawi

Unicef (2021) C_UNICEF

UNICEF Malawi and its partners are prioritizing renewable energy solutions for children and communities across the country to access clean and affordable electricity, with a focus on hard-to-reach, rural communities unable to access the national electricity grid.

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Building child-friendly and resilient communities

UN Children's Fund UNICEF (2021) CC

Imagine a child- friendly and resilient community in Malawi. A happy child, healthy parents, a latrine behind the house, livestock somewhere in the backyard, no-one panics when clouds come because people are prepared for the rain. At UNICEF, we are working with the Government and civil society of M... more

Healthy diet

World Health Organization WHO (2020) C_WHO

Key facts - A healthy diet helps to protect against malnutrition in all its forms, as well as noncommunicable diseases (NCDs), including diabetes, heart disease, stroke and cancer. - Unhealthy diet and lack of physical activity are leading global risks to health. - Healthy dietary practices start... more

Achieving Control of Asthma in Children in Africa (ACACIA): protocol of an observational study of children’s lung health in six sub-Saharan African countries

Mosler, G.; Oyenuga, V.; Addo-Yobo, E. et al. BMJ Open (2020) CC

Little is known about asthma control in the rising number of African children who suffer from this condition. The Achieving Control of Asthma in Children in Africa (ACACIA) study is an observational study collecting evidence about paediatric asthma in urban areas of Ghana, Malawi, Nigeria, South Afr... more

Childhood Asthma: Low and Middle-Income Countries Perspective

Soto-Martínez, M.E.; Soto-Quiros, M.E.; Custovic, A. Acta Medica Academica (2020) CC

Our aim is to review current asthma epidemiology, achievements from the last 10 years, and persistent challenges of asthma man- agement and control in low-middle income countries (LMICs). Despite global efforts, asthma continues to be an important public health problem worldwide, particularly in poo... more

Symptom-based screening tool for asthma syndrome among young children in Uganda

Nantanda, R.; Siersma, V.; Ndeezi, G. et al. npj Primary Care Respiratory Medicine (2020) CC

Under-diagnosis of asthma in ‘under-fives’ may be alleviated by improved inquiry into disease history. We assessed a questionnaire-based screening tool for asthma among 614 ‘under-fives’ with severe respiratory illness in Uganda. The questionnaire responses were compared to post hoc consensu... more

A worldwide charter for all children with asthma

Szefler, S. J.; Fitzgerald, D. A.; Adachi, Y.; (2020) CC2

Asthma is the commonest chronic childhood disease and encompasses a spectrum of airway diseases with similar symptoms. Inaccurate diagnosis remains common, especially in younger children, with failure to characterize the different “asthmas.” Children worldwide repeatedly suffer symptoms which se... more

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Impact of COVID-19 on Pediatric Asthma: Practice Adjustments and Disease Burden

Papadopoulos, N.G.; Custovic, A.; Deschildre, A. et al. The Journal of Allergy and Clinical Immunology: In Practice (2020) CC

Coronavirus disease 2019 has a mild disease course in children and adolescents. Chronic respiratory conditions, including asthma, have been suggested as risk factors; however, asthma in children is highly variable in both triggers and severity. During the pandemic, pediatric asthma services limite... more

Добро пожаловать в новой жизни

Stein, S. (2020) C1

Как детям живется после страшных переживаний и как можно им помочь. Собрание картин, составленное Сузаннэ Штайн (Susanne Stein) для разговоров с родителями детей, пережив... more

Ласкаво просимо в нове життя

Stein, S. (2020) C1

Як живеться дітям після пережитого надзвичайно великого страху і що їм може допомогти. Брошура Сюзанне Штайн (Susanne Stein) для розмов з батьками дітей, які пережили над�... more

Burden of fungal asthma in Africa: A systematic review and meta-analysis

Kwizera, R.; Musaazi, J.; Meya, D.B.; et al. PLOS ONE, which is part of the Public Library of Science (PLOS) (2019) CC2

Asthma is one of the neglected diseases in Africa with a high prevalence. Allergic fungal diseases have been reported to complicate asthma progression and treatment outcomes. However, data about fungal asthma and its associated complications are limited in Africa. We aimed to estimate the burden of ... more

Asthma treatment in children: A guide to screening for and management of hypothalamic-pituitary-adrenal axis suppression

Zöllner, E.W. South African Medical Journal (2019) CC

The article "Asthma treatment in children: A guide to screening for and management of hypothalamic-pituitary-adrenal axis suppression" discusses the risks associated with the use of corticosteroids in pediatric asthma treatment. It highlights that prolonged corticosteroid use can suppress the hypoth... more