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SCOPING QUESTION: For adults and children with medication-resistant convulsive epilepsy, which anti-epileptic medications produce benefits and/or harm in the specified outcomes when compared to a placebo or a comparator?
SCOPING QUESTION: In adults with established status epilepticus (i.e., seizures persisting after the first-line treatment with benzodiazepines [or benzodiazepines-resistant status epilepticus]), which anti-epileptic medications are associated with cessation of seizures and reduced adverse effects)? ... more
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Epilepsia, 55(4):475–482, 2014 doi: 10.1111/epi.12550
Received: 16/11/2013 - Accepted: 23/03/2014 - Published: 27/07/2014
Lancet 2012; 380: 1193–1201 Series: Epilepsy 2
Paediatrics Chapter I.2
Bulletin de l'Organisation mondiale de la Santé 2012;90:871-871A. doi: 10.2471/BLT.12.113183 Bulletin de l'Organisation mondiale de la Santé Numéros précédents Volume 90: 2012 Volume 90, Numéro 12, décembre 2012, 869-944
Q12: Should the treatment be similar in individuals with intellectual disability and epilepsy compared to people with epilepsy only?
www.jogh.org • doi: 10.7189/jogh.02.020405 ~ December 2012 • Vol. 2 No. 2 • 020405
Clinical guideline | Published: 11 January 2012 | nice.org.uk/guidance/cg137
Q 7: For adults and children with convulsive epilepsy, which standard antiepileptic drugs (phenobarbital, phenytoin, carbamazepine, valproic acid) when compared to placebo/a comparator produce benefits/harm in the specified outcomes?
BMC Medicine201210:107 https://doi.org/10.1186/1741-7015-10-107© Katchanov and Birbeck; licensee BioMed Central Ltd. 2012 Received: 10 July 2012Accepted: 24 September 2012Published: 24 September 2012 In 2011, the World Health Organization’s (WHO) mental health Gap Action Programme (mhGAP) r ... more
Q6: What is the added advantage of doing neuroimaging in people with convulsive epilepsy in non-specialist settings in low and middle income countries?
Q 10: In adults and children with epilepsy, which psychological interventions used as adjunctive therapies with antiepileptic drugs when compared to placebo/comparator produce benefits/harm in specified outcomes?
Q9. In adults and children with convulsive epilepsy in remission, when should treatment be discontinued?
Q3: Can febrile seizures (simple or complex) be managed at first or second level care by non-specialist health care providers in low and middle income country settings? What is the role of diagnostic tests in the management of febrile seizures by non-specialists in low and middle income settings? Fo ... more
Q5: What is the added advantage of doing an electroencephalography (EEG) in people with convulsive epilepsy in non- specialist settings in low and middle income countries?

Antiepileptic drug treatment after first unprovoked seizure

World Health Organization (2012) C_WHO
Q8. Should Anti-Epileptic Drug (AED) treatment be started after first unprovoked seizure in non-specialist health settings?