The Public Health Burden of Commercial Tobacco Use
The burden ...ht medbox">of disease and death from commercial tobacco* use in the United States is
overwhelmingly caused by cigarettes and other combustible tobacco products.
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The Early Childhood Development Policy and its Strategic Plan seek to provide a framework to ensure such a holistic and integrated approach to ...n class="attribute-to-highlight medbox">the development of young children. International research has demonstrated the high economic returns on ECD investment and its positive impact on healthand education outcomes as well as the overall economic development of a nation. The implementation ofthe ECD Policy will thus provide Rwanda with the basis for achieving the objectives and goals ofthe EDPRS and Vision 2020.
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This Review summarizes many ofthe persistent biological alterations associated with childhood maltreatment including changes in neuroendocrine and... neurotransmitter systems and pro-inflammatory cytokines in addition to specific alterations in brain areas associated with mood regulation. Finally, I discuss several candidate gene polymorphisms that interact with childhood maltreatment to modulate vulnerability to major depression and PTSD and epigenetic mechanisms thought to transduce environmental stressors into disease vulnerability.
Neuron Review, vol. 89, March 2, 2016 pp.892-909more